Welcome to the Janowiak lab web pages!
The Janowiak lab uses biochemistry, microbiology, and molecular genetics to explore the relationship between microbes and their environment. We have three main focuses:
1) Gram-positive pathogenic bacteria and their response to oxidative stresses produced by the mammalian host
2) Soil bacteria and their roles in biodiversity and organismal activity
3) The contribution of glutathione and other antioxidants to the survival and maintenance of bacteria residing in the mouse vaginal microbiome
Our bacteria of interest for the oxidative stress study (project focus 1) include Group B Streptococcus (Streptococcus agalactiae), Enterococcus faecalis, and Streptococcus pyogenes.
Our favorite oxidative stress response is glutathione, and we specifically study its synthesis, import, export, and metabolism in bacteria.
For our soil microbiome study (project focus 2), we are examining glutathione metabolism (import and synthesis), cellulase activity, nitrogen metabolism, antibiotic production, and antibiotic resistance.
The soil microbiome study projects are split between a hands-on upper-division biology course and independent research in my lab.
The third project focus is a combination of the first two project focuses in which we are interested in the role antioxidants play in maintaining a healthy vaginal microbiome. Group B Streptococcus is often found in the healthy vaginal microbiome, but can become an opportunistic pathogen and cause significant disease.
For more information about our research, please feel free to contact me at bjanowia[at]slu.edu
Please navigate our various pages using the links on the top.
Thanks for visiting!
Last updated: September, 2014
The Janowiak Lab in the Fall of 2014
The Crew of Summer 2014!
The Crew of Fall 2013!
The Crew of Summer 2013!
A subset of "Team Strep" after presenting our work at the Biology Department Symposium