Embedded Files
This is a picture of the AKI research group in the Fall of 2015.
This custom-built hypoxia chamber enables us to study hypoxia - induced injury to the kidney.
This slide shows a PAS stained section of a kidney caused by 30 minutes of ischemia-reperfusion-injury (IRI). Glomeruli and tubular casts are evident in the section.
The goal of the AKI research group is to identify novel metabolic biomarkers of AKI using a combination of NMR and LC/MS based metabolic profiling. We are currently conducting mouse model studies to investigate 1) hypoxia, 2) ischemia-reperfusion-injury, 3) nephrotoxin, and sepsis models of AKI. Histological and immunohistological studies are performed to all correlation of metabolic profiling data with detailed information regarding structural and cellular level changes that take place in the kidney following injury.
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