Essential Idea
Chromosomes carry genes in a linear sequence that is shared by members of a species.
Understandings
Prokaryotes have one chromosome consisting of a circular DNA molecule.
Some prokaryotes also have plasmids but eukaryotes do not.
Eukaryote chromosomes are linear DNA molecules associated with histone proteins.
In a eukaryotic species there are different chromosomes that carry different genes.
Homologous chromosomes carry the same sequence of genes but not necessarily the same alleles of those genes.
Diploid nuclei have pairs of homologous chromosomes.
Haploid nuclei have one chromosome of each pair.
The number of chromosomes is a characteristic feature of members of a species.
A karyogram shows the chromosomes of an organism in homologous pairs of decreasing length.
Sex is determined by sex chromosomes and autosomes are chromosomes that do not determine sex.
Applications
Cairns' technique for measuring the length of DNA molecules by autoradiography.
Comparison of genome size in T2 phage, Escherichia coli, Drosophila melanogaster, Homo sapiens and Paris japonica.
Comparison of diploid chromosome numbers of Homo sapiens, Pan troglodytes, Canis familiaris, Oryza sativa, Parascaris equorum.
Textbook Reading and/or Activities
Click HERE for a pdf of chapter 3.
Pages 134-142
Challenge Yourself (p.138)
Exercises (p.142)
Notes
A detailed set of notes, prepared by Bob Smullen, examining all of the IB learning expectations.
A detailed set of notes, prepared by Stephen Taylor, examining U1 - U10 and A4.
i-Biology Study Questions (Not available)
A series of questions, prepared by Stephen Taylor, to help check your understanding of the IB learning expectations. This is VERY GOOD practice.
A detailed set of notes, created by Chris Paine, examining all of the IB learning expectations.
A series of questions, created by Chris Paine, to help check your understanding of the IB learning expectations. This isVERY GOOD practice.
A detailed set of notes, prepared by Jacob Cedarbaum, examining all of the IB learning expectations.
3.2 Study Questions (NEW Syllabus)
A series of questions, prepared by Jacob Cedarbaum, to help check your understanding of the IB learning expectations. This is VERY GOOD practice. Answers (OLD).
Learning Activities
This short activity, prepared by the University of Utah, will help you better understand chromosomes and how they are organized into homologous pairs based on size and shape.
Karyotyping and Genetic Disorders
Read through and complete this series of activities, prepared by the University of Arizona, to practice compiling karyotypes and diagnosing genetic disorders based on the karyogram.
More karyotyping and diagnostic practice, prepared by Biology Corner.
Supplemental Reading
This video outlines what plasmids are and how they are important to gene transfer between prokaryotes and for genetic modifications in eukaryotes.
This video examines U8 and A2.
Supplemental Videos
Video Tutorials
Image: Pearson Baccalaureate Standard Level Biology 2nd Ed.
Use of karyograms to deduce sex and diagnose Down syndrome in humans.
Skills
Use of databases to identify the locus of a human gene and its polypeptide product.
Key Vocabulary
Chromosome
Homologous
Locus
Gene
Allele
Prokaryote
Circular chromosome
Plasmid
Eukaryote
Linear chromosomes
Histone
Haploid
Diploid
Autosome
Sex chromosome
Karyogram
Karyotype
Autoradiography
Cairns' technique
This video examines the difference between diploid and haploid cells and outlines the importance of gametes being haploid cells.
This video outlines the structure of eukaryotic DNA as well as how genes are organized within the molecule.