If it's easier to listen than to read, try...

Kurzweil 3000

Kurzweil 3000 reads articles, books, and other materials out loud--including web pages. It also offers writing features, including word prediction, mind mapping, and outlining.

Read&Write

Read&Write reads text in EPUB books, Microsoft Word files, PDFs, websites, and Google Docs. It also offers writing tools such as outlines and word prediction.

NaturalReader

This text-to-speech reader is easy to use. A basic free version reads text in most file formats and has a "floating bar" that reads text on webpages; premium versions let you create audio files from text, type with word prediction, and more. It's available on the Web and as Windows and Mac downloads.

ClaroPDF

ClaroPDF is a text-to-speech app that runs on Apple iPhones and iPads, Android phones and tablets, and Windows PCs.

Speechify

Speechify is a text-to-speech app that runs on Apple iPhones, iPads, and Macbooks (there is also a Chrome extension). The Mac/iOS versions are more versatile than the Chrome options (which reads only text selected in the Web browser).

C-Pen Reader

Use this hand-held device to scan printed text and have it read to you. The scanned text can be uploaded to a computer. The C-Pen also includes a built-in dictionary and translation features.

Mobile Scanning Apps: Prizmo Go, Text Fairy

These free mobile apps let you take a picture of any text (a label, say, or a sign), then they read the text out loud to you.