HExaT Programme

Draft programme

Wednesday 22nd April 2026

13:00-18:00: Pre-meeting workshop for hands-on HSC culture, supported by STEMCELL Technologies

18:00: Social event at BrewYork

Pre-booking required. This workshop and social event is now fully booked, but if still interested, please email david.kent@york.ac.uk to be put on a waiting list should places become available.

Thursday 23rd April 2026

8:30-9:15: Registration

9:15-10:40: HSC technologies session

Welcome and notices 

Satoshi Yamazaki (keynote) - Predicting Hematopoiesis: A Laplace Perspective on Stem Cell Dynamics

Maria Jassinskaja (short-talk) - Proteomic and secretomic characterization of ex vivo expanded hematopoietic stem cells identifies drivers and predictors of self-renewal in culture

Matthew Nicholls (short-talk) - A robust ex vivo limiting dilution assay to quantify HSC self-renewal and lineage potential

Shintaro Watanuki (short-talk) - Identification of an Endogenous Factor that Supports the Long-Term Maintenance of Hematopoietic Stem Cells Ex Vivo

Sponsor presentation          

10:40-11:10: Break            

11:10-12:30: HSC biology session        

Timm Schroeder (keynote) - Long-term single live cell quantification: New tools for old questions

Adrienne Dorrance (short-talk) - Epithelial Growth Factor Like-7 (EGFL7) regulates hematopoiesis stem cell cycle via AP-1 suppression

Maciej Cieśla (short-talk) - Translational Regulation of Sf1 Integrates Splicing and Hematopoietic Stem Cell Fate

Hanna Eriksson (short-talk) - CRISPR screening in human HSPCs identifies the RNA helicase DDX6 as a novel HSC regulator

Sponsor presentation          

12:30-13:30: Lunch and poster session          

13:30-14:50: Signalling and interactions         

Marike Essers (keynote) - Long-term ex vivo expansion of murine and human Hematopoietic Stem Cell (HSC) using bone-derived Mesenchymal Stromal Cells

Maorong Xie (short-talk) - Modified cytokines as a new tool to direct hematopoietic stem cell fate

Lauren Randolph (short-talk) - A hemogenic inductive role for HSC maintenance media

Ioannis Angelos Tsigkos (short-talk) - Modelling Cancer Cell Dormancy in an Engineered Endosteal Niche Using an artificial Self-Structuring Bone Model (SSBM)

Sponsor presentation          

14:50-15:20: Break            

15:20-16:30: Disease modelling

Alejo Rodriguez-Fraticelli (keynote) - Single-cell lineage tracing in expansion cultures of normal and malignant blood stem cells

Marta Cecylia Tapia (short-talk) - Modelling VEXAS - a newly identified hematopoietic/inflammatory syndrome

Stef Van den Bergh (short-talk) - Exploring the non-canonical function of EZH2 in T-cell acute lymphoblastic leukemia

Deborah Martinuzzi (short-talk) - The Impact of Prototypical Myeloid Neoplasm Mutations on the Functional Heterogeneity of Hematopoietic Stem and Progenitor Cells

16:30-17:00: Break

17:00-18:00: Therapeutic applications

Elisa Laurenti (keynote) - Human haematopoietic stem cells adaptation to ex vivo culture at single cell resolution

Borko Amulic (short-talk) - Neutrophils cultured from CD34+ HSPCs show enhanced efficacy and therapeutic potential

Aaron Tze Kai Tan (short-talk) - GUSTOF: Overcoming Human Hematopoietic Stem Cell Scarcity Through Robust ex vivo Expansion

Closing remarks

18:00-20:00: Social event and poster session           

Friday 24th April 2026

9:00-13:00: Post-meeting workshop for image-enabled cell sorting, supported by BD

Pre-booking required. This workshop is now fully booked, but if still interested, please email david.kent@york.ac.uk to be put on a waiting list should places become available.