HExaT Programme

Programme

Wednesday 22nd April 2026:

12:00-18:00: Pre-meeting HSC culture workshop

Pre-meeting workshop generously sponsored by Stem Cell Technologies. Please note that this pre-meeting workshop is now fully booked, but if still interested, please email david.kent@york.ac.uk to be put on a waiting list should places become available.

18:00: Social event @ Brew York 

Thursday 23rd April 2026: Main meeting @ York Guildhall (Coney St, York YO1 9QN)

8:30-9:15: Registration and coffee

9:15-10:40: HSC technologies session

Welcome and notices

Satoshi Yamazaki (University of Tokyo) - Predicting Hematopoiesis: A Laplace Perspective on Stem Cell Dynamics (keynote)

Maria Jassinskaja (Lund University) - Proteomic and secretomic characterization of ex vivo expanded hematopoietic stem cells identifies drivers and predictors of self-renewal in culture (short-talk)

Matthew Nicholls (University of Oxford) - A robust ex vivo limiting dilution assay to quantify HSC self-renewal and lineage potential (short-talk)

Shintaro Watanuki (Tohoku University) - Identification of an Endogenous Factor that Supports the Long-Term Maintenance of Hematopoietic Stem Cells Ex Vivo (short-talk)

Gold sponsor presentation from Celaid Therapeutics           

10:40-11:10: Coffee break    

11:10-12:30: HSC biology session  

Timm Schroeder (ETH Zurich) - Long-term single live cell quantification: New tools for old questions (keynote)

Adrienne Dorrance (University of Utah) - Epithelial Growth Factor Like-7 (EGFL7) regulates hematopoiesis stem cell cycle via AP-1 suppression (short-talk)

Maciej Cieśla (IMol Polish Academy of Sciences) - Translational Regulation of Sf1 Integrates Splicing and Hematopoietic Stem Cell Fate (short-talk)

Hanna Eriksson (Lund University) - CRISPR screening in human HSPCs identifies the RNA helicase DDX6 as a novel HSC regulator (short-talk)

Gold sponsor presentation from Frontiers in Hematology

12:30-13:30: Lunch and poster session     

13:30-14:50: Signalling and cell interactions session

Marike Essers (Heidelberg Institute for Stem Cell Technology and Experimental Medicine) - Long-term ex vivo expansion of murine and human Hematopoietic Stem Cells using bone-derived Mesenchymal Stromal Cells (keynote)

Maorong Xie (University of York) - Modified cytokines as a new tool to direct hematopoietic stem cell fate (short-talk)

Lauren Randolph (Ospedale San Raffaele/SR-TIGET) - A hemogenic inductive role for HSC maintenance media (short-talk)

Ioannis Angelos Tsigkos (University of Glasgow) - Modelling Cancer Cell Dormancy in an Engineered Endosteal Niche Using an artificial Self-Structuring Bone Model (short-talk)

Gold sponsor presentation from Miltenyi Biotec

14:50-15:20: Coffee break    

15:20-17:00: Disease modelling to therapeutic applications session

Alejo Rodriguez-Fraticelli (IRB Barcelona/ICREA) - Single-cell lineage tracing in expansion cultures of normal and malignant blood stem cells (keynote)

Renata de Britto (BRIC University of Copenhagen) - Modelling VEXAS - a newly identified hematopoietic/inflammatory syndrome (short-talk)

Deborah Martinuzzi (University of Cambridge) - The Impact of Prototypical Myeloid Neoplasm Mutations on the Functional Heterogeneity of Hematopoietic Stem and Progenitor Cells (short-talk)

Stef Van den Bergh (KU Leuven) - Exploring the non-canonical function of EZH2 in T-cell acute lymphoblastic leukemia (short-talk)

Elisa Laurenti (University of Cambridge) - Human haematopoietic stem cells adaptation to ex vivo culture at single cell resolution (keynote)

Closing remarks

17:00-21:00: Poster session followed by social event     

Friday 24th April 2026:

9:00-14:00: Post-meeting image-enabled cell sorting workshop 

Post-meeting workshop generously sponsored by BD Biosciences. Please note that this post-meeting workshop is now fully booked, but if still interested, please email david.kent@york.ac.uk to be put on a waiting list should places become available.