It is mainly conducting research on electrical stimulation, and previous studies have studied the effect of promoting hair growth through animal experiments to promote hair growth, and PCR analysis has been conducted on various hair growth factors.

By causing acne, we evaluated whether electrical stimulation is effective in relieving acne. Cells were treated with peptide glocan (PGN) and observed through confocal microscopy, and we evaluated whether microelectrical stimulation was effective through Western blotting. After the experimental results, the experimental results were obtained that microelectrical stimulation is effective in relieving acne.

We used full-fat cells 3T3-L1 and tried to find a more effective stimulation intensity at 200 microampeas and 400 microampeas by varying the microelectrical stimulation intensity. As you can see in the figure on the right, it corresponds to the epididymal fat of the animal tissue, and the size of the tissue decreased significantly in the 400 microampea group. It means that the accumulation of lipids inhibits the lipid production in the 400 microampea group.

We evaluated the effect of microcurrent stimulation on lipid metabolism in non-alcoholic fatty liver disease caused by oleic acid, and in mice fed a high-fat diet, several protein factors related to lipid production were found to have significant efficacy in the 400 microampea group.

It is related to degenerative arthritis, which is often attracting attention, and in order to evaluate the effect of microcurrent stimulation on osteoarthritis, we researched whether microcurrent stimulation inhibits the progression of osteoarthritis after injecting arthritis-causing drugs into mouse cartilage.

Simulated microgravity was generated using a clinostat-based RPM system.  Cancer cell spheroids cultured under low and high RPM conditions showed altered morphology and increased compactness compared to static culture. Quantitative analysis revealed changes in spheroid size and shape. Cell viability and live/dead staining results indicated that simulated microgravity affects cell survival in a condition-dependent manner.