Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor. Doxtader KA, Wang P, Scarborough AM, Seo D, Conrad NK, Nam Y. Molecular Cell. 2018 Sep 5. pii: S1097-2765(18)30594-X. doi: 10.1016/j.molcel.2018.07.025. PMID: 30197297

Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28. Wang L, Rowe RG, Jaimes A, Yu C, Nam Y, Pearson DS, Zhang J, Xie X, Marion W, Heffron GJ, Daley GQ, Sliz P. Cell Rep. 2018 Jun 5;23(10):3091-3101. doi: 10.1016/j.celrep.2018.04.116. PMID: 29874593.

Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs Partin AC, Ngo TD, Herrell E, Jeong BC, Hon G, Nam Y. Nat Commun. 2017 Nov 23;8(1):1737. doi: 10.1038/s41467-017-01713-y.

LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation. Wang L, Nam Y, Lee AK, Yu C, Roth K, Chen C, Ransey EM, Sliz P. Cell Rep. 2017 Mar 14;18(11):2664-2675.

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases. Wang P, Doxtader KA, Nam Y. Molecular cell. 2016; 63(2):306-17.

HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing. Liu H, Liang C, Kollipara RK, Matsui M, Ke X, Jeong BC, Wang Z, Yoo KS, Yadav GP, Kinch LN, Grishin NV, Nam Y, Corey DR, Kittler R, Liu Q. Molecular cell. 2016; 63(3):420-32.

Data publication with the structural biology data grid supports live analysis. Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, Bonvin AM, Borek D, Brett TJ, Caflisch A, Chang CI, Chazin WJ, Corbett KD, Cosgrove MS, Crosson S, Dhe-Paganon S, Di Cera E, Drennan CL, Eck MJ, Eichman BF, Fan QR, Ferré-D'Amaré AR, Christopher Fromme J, Garcia KC, Gaudet R, Gong P, Harrison SC, Heldwein EE, Jia Z, Keenan RJ, Kruse AC, Kvansakul M, McLellan JS, Modis Y, Nam Y, Otwinowski Z, Pai EF, Pereira PJ, Petosa C, Raman CS, Rapoport TA, Roll-Mecak A, Rosen MK, Rudenko G, Schlessinger J, Schwartz TU, Shamoo Y, Sondermann H, Tao YJ, Tolia NH, Tsodikov OV, Westover KD, Wu H, Foster I, Fraser JS, Maia FR, Gonen T, Kirchhausen T, Diederichs K, Crosas M, Sliz P. Nature communications. 2016; 7:10882.

A grid-enabled web service for low-resolution crystal structure refinement. O'Donovan DJ, Stokes-Rees I, Nam Y, Blacklow SC, Schröder GF, Brunger AT, Sliz P. Acta crystallographica. Section D, Biological crystallography. 2012; 68(Pt 3):261-7.

Conformational locking upon cooperative assembly of notch transcription complexes. Choi SH, Wales TE, Nam Y, O'Donovan DJ, Sliz P, Engen JR, Blacklow SC. Structure. 2012 Feb 8;20(2):340-9.

Molecular basis for interaction of let-7 microRNAs with Lin28. Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P. Cell. 2011 Nov 23;147(5):1080-91.

Structure of human O-GlcNAc transferase and its complex with a peptide substrate. Lazarus MB, Nam Y, Jiang J, Sliz P, Walker S. Nature. 2011; 469(7331):564-7.

Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation. Aster JC, Bodnar N, Xu L, Karnell F, Milholland JM, Maillard I, Histen G, Nam Y, Blacklow SC, Pear WS. PLoS One. 2011;6(10):e25645.

A role for the two-helix finger of the SecA ATPase in protein translocation. Erlandson KJ, Miller SB, Nam Y, Osborne AR, Zimmer J, Rapoport TA. Nature. 2008; 455(7215):984-7.

Structure of a complex of the ATPase SecA and the protein-translocation channel. Zimmer J, Nam Y, Rapoport TA. Nature. 2008; 455(7215):936-43.

Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription. Nam Y, Sliz P, Pear WS, Aster JC, Blacklow SC. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104(7):2103-8.

Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1. Chiang MY, Xu ML, Histen G, Shestova O, Roy M, Nam Y, Blacklow SC, Sacks DB, Pear WS, Aster JC. Molecular and cellular biology. 2006; 26(16):6261-71.

Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes. Nam Y, Sliz P, Song L, Aster JC, Blacklow SC. Cell. 2006; 124(5):973-83.

Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex. Nam Y, Weng AP, Aster JC, Blacklow SC. The Journal of biological chemistry. 2003; 278(23):21232-9.

Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling. Weng AP, Nam Y, Wolfe MS, Pear WS, Griffin JD, Blacklow SC, Aster JC. Molecular and cellular biology. 2003; 23(2):655-64.

Notch signaling as a therapeutic target. Nam Y, Aster JC, Blacklow SC. Current opinion in chemical biology. 2002; 6(4):501-9.