Embedded Files
A Look into Making Proteins
A Look into Making Proteins
Mutations
Mutations
Protein Mutation Project
Protein Mutation Project
Background
Background
From what we have learned, DNA can become mutated when there is a mistake made when DNA is being replicated. Ultimately, if there is a mistake in the process, the protein/gene that is supposed to be coded can end up being altered. More times than not, that mutation is negative and leads to dysfunctioning proteins. But, what about the other small percentage of mutations that lead to a good adaptation? What could that look like in animals, or in humans?
Real Life Mutations In Chernobyl
Real Life Mutations In Chernobyl
Part 1 - Origin and Discovery
Part 1 - Origin and Discovery
Two Paragraph Introduction
Two Paragraph Introduction
1. Write about the finding of this mutation. How was this discovered? Was it a natural mutation, from radiation/scientific intervention?
1. Write about the finding of this mutation. How was this discovered? Was it a natural mutation, from radiation/scientific intervention?
Is it seen in one animal, multiple animals, only one case, is it prevalent in one area?
Is it seen in one animal, multiple animals, only one case, is it prevalent in one area?
Is this mutation positive/negative/neutral for the survival of this animal?
Is this mutation positive/negative/neutral for the survival of this animal?
Would it be beneficial to control the spreading of this mutation?
Would it be beneficial to control the spreading of this mutation?
Would this mutation be a potential new trait that we could use in medicine or treatments?
Would this mutation be a potential new trait that we could use in medicine or treatments?
2. What seems to be the main protein/gene that was mutated for us to see the phenotype you are describing as your main idea?
2. What seems to be the main protein/gene that was mutated for us to see the phenotype you are describing as your main idea?
What is the function of the protein normally?
What is the function of the protein normally?
What type of mutation occurred for this mutation to happen (substitution, insertion, deletion)?
What type of mutation occurred for this mutation to happen (substitution, insertion, deletion)?
How did this mutation ultimately see a change in the gene/protein (what happened to the amino acid sequence)
How did this mutation ultimately see a change in the gene/protein (what happened to the amino acid sequence)
Part 2 - Display of the Mutation
Part 2 - Display of the Mutation
Diagram of Mutation
Diagram of Mutation
Example: Making a human who adapted a nictitating membrane like the Crocodile or Eagle.
Requirements
Requirements
- Protein Synthesis
Use the image to the left for support (Note: mRNA was skipped in the image)
Use the image to the left for support (Note: mRNA was skipped in the image)
1. Obtain the DNA sequence about the protein or the gene for your project. Draw out that sequence on a piece of paper and label it DNA.
2. Convert the DNA to mRNA and then to the Amino Acids
3. Repeat this but add the mutation. Do this right underneath the normal strand. Make sure to label the mutation on the poster. **You are required to make a minimum of two different mutations that we have covered in class**
4. Convert the mutated DNA to mRNA and then to the Amino Acids. Make sure to label how the amino acids are altered from the mutation.
2. Diagram
2. Diagram
Use the example to the left. I would change the last image to look like a functional nictitating membrane for a better grade!
Use the example to the left. I would change the last image to look like a functional nictitating membrane for a better grade!
Create a diagram that people can visually see the mutation for your project. The diagram can be hand drawn, done on the computer (photoshop, paint, google drawings).
If the mutation is based off of another animal or object, include the inspiration as well.
Final Project Submission
Final Project Submission
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