Embedded Files
Curriculm Vitae
DE P A R T M E N T O F CH E M I S T R Y
ROBERT J. HINKLE 22 October 2025
OFFICE ADDRESS:
Department of Chemistry
2043 Integrated Science Center
William & Mary
Williamsburg, VA 23187-8795
(757) 221-7536
e-mail: rjhink@wm.edu
web: https://sites.google.com/email.wm.edu/hinklelabwm/home
CURRENT POSITION:
DEPARTMENT: Chemistry
Professor, August 2011 to present.
EDUCATION
Ph. D. in Organic Chemistry: Univ. of Utah, 1994–Peter J. Stang, Distinguished Professor.
Thesis Title: Conjugated Enynes and Dienes: Platinum Model Studies of Proposed
Catalytic Intermediates and New Synthetic Methods.
A. B.: Bowdoin College, 1986. Cum Laude, Summa Cum Laude in Chemistry.
ACADEMIC POSITIONS
-Vice-Dean for Natural, Physical, and Computational Sciences & Interdisciplinary Studies, July 2021 to June 2025
-Visiting Scholar, Vanderbilt University, under invitation of Professor Jeffrey N. Johnston; August 2016 to December 2016.
-Professor of Chemistry, William & Mary; August 2011 to present.
-Visiting Scholar, Indiana University under invitation of Professor P. Andrew Evans; July
2002 to December 2002.
-Associate Professor of Chemistry, William & Mary; August 2002 to August 2011.
-Assistant Professor of Chemistry, William & Mary; August 1996 to
August 2002.
-Research Scientist, University of California, Irvine; 12 January 1996 to 15 July 1996.
-National Institutes of Health Postdoctoral Fellow, University of California, Irvine; January 1994 to January 1996. Larry E. Overman as advisor.
HONORS, PRIZES AND AWARDS
• Cottrell Scholar Class of 1998, Research Corporation, Tucson, AZ
• Plummeri Award for Faculty Excellence recipient 2015-2017, William & Mary.
• Jennifer and Devin Murphy Faculty Award for outstanding integration of research with
teaching, 2014-1016, William & Mary.
• NSF–Invited Participant (ONLY PUI faculty member of 20, with 19 from R01 Institutions); Workshop on Organic Synthesis and Natural Products Chemistry, 2008.
• Henry Dreyfus Teacher-Scholar Award, $60,000, October 2002 to October 2007.
• Gordon Research Conference (Organic Reactions and Processes) Poster Award, 2007.
• NSF Early CAREER Award, 1999.
• Honorary Member of Eta Sigma Pi Honor Society.
• Honorary Member of Phi Eta Sigma Honor Society.
• Phi Kappa Phi, The University of Utah; April 1993.
• Stauffer Scholarship for Academic Excellence, University of Utah; April 1988, $250.
COURSES TAUGHT
Chemistry 150W/275W: Beyond Petroleum as a Fuel F, ’06, ’07, ’10, ‘11
Chemistry 206; Organic Chemistry I S, ’04-‘06, ’11-‘16
Chemistry 209; Organic Chemistry II for Concentrators. F, ’96-'01, ’08, ’12-’15, ’18-‘20
Chemistry 457; Organic Synthesis (Senior Level course) S, ’00-'03,’09, ’16, ’18-‘22
Chemistry 557/657; Organic Synthesis (M.S. Level course). S, ’00-'03,’09, ’16, ’18-‘22
Chemistry 252(206L); Organic Laboratory I. S, ’97-’00, ’04, ’05, ’08-’09, ’11-’16, ’1 7-‘20
Chemistry 252; Organic Laboratory I (IN CHARGE). S, ‘01, '02, ’05, ’06, ’07
Chemistry 291; Undergraduate Research F, ‘96 to present
Chemistry 353 (253); Organic Laboratory II. F, ’97 -'01, '05-’09, ’11-’16, ’18-’20
Chemistry 353; Organic Laboratory II (IN CHARGE). F, ’03-‘07, ’11, ‘13
Chemistry 409; Senior Research. F, ‘97 to present
Chemistry 495/6; Honors Research. F, ‘96 to present
Chemistry 320; Introduction to Research F, ‘96 to ‘16
Publications in Refereed Journals (W&M undergraduate names underlined).
1) Caleb L. Burns, Katherine U. Kim, Kevin M. McFadden, Robert J. Hinkle,* and Robert D. Pike.* “Synthesis of Helical Chromeno[3,4-c]chromenes via a Multistep Synthetic Pathway Utilizing an Alkyne-Prins Cyclization Reaction,” Submitted to Organic & Biomolecular Chemistry, 01 October 2025.
2) Tyler L. Skeen, Rebekah L. Gresham, Katherine A. Agamaite, Olivia M. Molz, Isabelle F. Westlake, Sage M. Kregenow, Al K. Romero, Brian M. Flood, Lauren E. Mazur, Robert J. Hinkle * and Douglas D. Young,* “Elucidation of Antimicrobials and Biofilm Inhibitors Derived from a Polyacetylene Core,” Molecules 2024, 29, 5945-5957. (https://doi.org/10.3390/molecules29245945).
3) Emma A. Hale††, Hannah M. Ryan††, Alexandra M. McOsker††, Cody M. Funk, Lauren C. Green, Lauren E. Mazur, Diya M. Uthappa, Brian M. Flood, Douglas D. Young*, Robert J. Hinkle,* “Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings,” Chem. Med. Chem. e202200455. First published: 04 October 2022 (https://doi.org/10.1002/cmdc.202200455)
Final paper published online, 29 October 2022. †† co-authors contributed equally.
4) Robert J. Hinkle, Daniel J. Speer, Brendon B. Carnell, Bethany L. Kanter, Robert D. Pike, “Mild, Modular and Convergent Synthesis of Helical Naphtho[2,1-c]chromenes via a Multistep Cyclization/Aromatization Cascade Sequence,” J. Org. Chem. 2019, 84, 15633-15641. Published online 05 November 2019; (https://doi.org/10.1021/acs.joc.9b02058.)
5) Robert J. Hinkle, Sarah E. Bredenkamp, Robert D. Pike, Seong Ik Cheon, “Electrophilic Cyclization of Phenylalkynediols to Naphthyl(aryl)iodonium Triflates with Chelating Hydroxyls: Preparation and X-ray Analyses ,” J. Org. Chem. 2017, 82, 11781. ASAP published online 17 August 2017; (http://pubs.acs.org/doi/pdf/10.1021/acs.joc.7b01619).
6) Robert J. Hinkle, Yuzhou Chen, Colleen Nofi, and Shane E. Lewis, “Electronic Effects on a One-pot Aromatization Cascade Involving Alkynyl-Prins Cyclization,Friedel–Crafts Alkylation and Dehydration to Tricyclic benzo[f]isochromenes,” Org. Biomol. Chem.
2017, 15, 7584-7593; DOI: 10.1039/c7ob01412k; (http://pubs.rsc.org/en/Content/ArticleLanding/2017/OB/C7OB01412K).
7) Robert J. Hinkle and Shane E. Lewis, “Atom Economical, One-Pot, Three-Reaction Cascade to Novel Tricyclic 2,4-Dihydro-1H-benzo[f]isochromene Derivatives,” Org. Lett. 2013, 15, 4070-4073. ASAP published online 01 August 2013; (http://dx.doi.org/10.1021/ol401600)j).
8) Frederick Lambert, Robert J. Hinkle,* Stephen E. Ammann, Yajing Lian, Jia Liu, Shane E. Lewis, and Robert D. Pike, “Bi(OTf)3-, TfOH-, and TMSOTf-Mediated, One-Pot Epoxide Rearrangement, Addition, and Intramolecular Silyl-Modified Sakurai (ISMS) Cascade toward Dihydropyrans: Comparison of Catalysts and Role of Bi(OTf)3,” J. Org. Chem. 2011, 76, 9269-9277; (https://pubs.acs.org/doi/10.1021/jo201478d).
9) Robert J. Hinkle,* Yajing Lian, Lee C. Speight, Heather E. Stevenson, Melissa M. Sprachman, Lauren A. Katkish, M. Christa Mattern, “Synthesis of 2,6-Disubstituted Dihydropyrans via an Efficient BiBr3-initiated Three Component, One-pot Cascade,” Tetrahedron 2009, 65, 6834–6839.
10) Yajing Lian, Robert J. Hinkle, ”BiBr3-Initiated Tandem Addition/Silyl-Prins Reactions to 2,6-Disubstituted Dihydropyrans,” J. Org. Chem. 2006, 71, 7071-7074; (https://pubs.acs.org/doi/10.1021/jo060738k).
11) Robert J. Hinkle, Yajing Lian, Nichole D. Litvinas, Alex T. Jenkins, Daniel C. Burnette, "BiBr3 Initiated Cyclization-Addition Reactions: Effect of Nucleophile and Total Synthesis of (+)-(S,S)-(cis-6-methyltetrahydropyran-2-yl)acetic Acid and its trans- Diastereomer," Tetrahedron 2005, 61, 11679-11685; (https://doi.org/10.1016/j.tet.2005.09.045).
12) Evans, P. A.; Cui, J.; Gharpure, S. J; Hinkle, R. J. “Stereoselective Construction of Cyclic Ethers using a Tandem Two-Component Etherification: Elucidation of the Role of Bismuth Tribromide,” J. Am. Chem. Soc. 2003, 125, 11456-11457; (https://pubs.acs.org/doi/10.1021/ja036439j).
13) Hinkle, R. J. "Mikowski, A. M. "Kinetics of Stereoisomeric 2-Methyl-1-butenyl- (aryl)iodonium Triflates," Included in a special issue of ARKIVOC 2003, vi, 201-212, published 25 July 2003; (http://www.arkat-usa.org/ark/journal/2003/Varvoglis/AV-
14) Tykwinski, R. R.†; Kamada, K.‡; Bykowski, D.†; Hegmann, F. A.†; Hinkle, R. J. "Nonlinear Optical Properties of Thienyl and Bithienyl Iodonium Salts as Measured by the Z-scan Technique," J. Opt. A: Pure Appl. Opt. 2002, 4, S202-206; (https://iopscience.iop.org/article/10.1088/1464-4258/4/6/353).
15) Bykowski, D.†; McDonald, R.†; Hinkle, R. J.; Tykwinski, R. R.† "Structural and Electronic Characteristics of Thienyl(aryl)iodonium Triflates," J. Org. Chem., 2002, 67, 2798-2804; (https://pubs.acs.org/doi/10.1021/jo015910t).
16) Hinkle, R. J.; McDonald, R.†, "(Z)-2-Methyl-1-buten-1-yl(aryl)iodonium Triflates Containing Electron-Withdrawing Groups on the Aryl Moiety." Acta Cryst. C. 2002, C58, o117-o121; (https://onlinelibrary.wiley.com/iucr/doi/10.1107/S0108270101019084).
17) McNeil, A. J.; Hinkle, R. J.; Rouse, E. A.; Thomas, Q. A.; Thomas, D. B. "Vinyl Carbocations: Solution Studies of Alkenyl(aryl)iodonium Triflate Fragmentations," J. Org. Chem. 2001, 66, 5556-5565; (https://pubs.acs.org/doi/10.1021/jo015746%2B).
18) Hinkle, R. J.; Leri, A. C.; David, G. A.; Erwin, W. M. "Addition of Benzylzinc Halides to Alkenyl(phenyl)iodonium Triflates: Stereoselective Synthesis of Trisubstituted Alkenes," Org. Lett. 2000, 2, 1521-1523; (https://pubs.acs.org/doi/10.1021/ol005682%2B).
19) Hinkle, R. J.; McNeil, A. J.; Thomas, Q. A.; Andrews, M. N. “Vinyl Cations in Solution: Kinetics and Products of Alkenyl(aryl)iodonium Salt Fragmentations,” J. Am. Chem. Soc., 1999, 121, 7437-7438.
20) Hinkle, R. J.; Thomas, D. B. “Facile Fragmentations of Alkenyl(aryl)iodonium Triflates,”J. Org. Chem. 1997, 62, 7534-7535; (https://pubs.acs.org/doi/10.1021/jo971132m).
21) Hinkle, R. J.; Stang, P. J. "Stereospecific Synthesis of Trisubstituted Alkenyl(phenyl)- iodonium Salts from Vinylstannanes" Synthesis 1994, 313.
22) Hinkle, R. J.; Poulter, G. T.; Stang, P. J. "Palladium(II) and Copper(I) Co-Catalyzed Coupling of Stereodefined Alkenyl(phenyl)iodonium Salts and Unsaturated Tri-n-butyl- stannanes" J. Am. Chem. Soc. 1993, 115, 11626; (https://pubs.acs.org/doi/abs/10.1021/ja00077a083).
23) Hinkle, R. J.; Stang, P. J.; Arif, A. M. "Vinylplatinum Carbenes and Nitriles, Platinoxacyclic Complexes and Heck-Type Coupling Products Formed Via Reaction of (sigma-2-propenyl)bis(triphenylphosphine)platinum(II) Triflate with Alkynols, Nitriles, and Acrylate Esters. Molecular Structure of [(PPh3)2PtCH2C(O)OCH3] [OTf]" Organometallics 1993, 12, 3510; (https://pubs.acs.org/doi/10.1021/om00033a023).
24) Zhong, Z.; Hinkle, R. J.; Arif, A. M.; Stang, P. J. "Novel Synthesis of (h3-Allyl)platinum(II) Complexes from Enol Triflates and Simple Olefins and Their Regiospecific Deprotonation" J. Am. Chem. Soc. 1991, 113, 6196; (https://pubs.acs.org/doi/10.1021/ja00016a040).
25) Hinkle, R. J.; Stang, P. J.; Kowalski, M. H. "Vinylphosphonium Salts: Stereoselective Palladium-Catalyzed Vinylation of Triphenylphosphine with Vinyl Triflates" J. Org. Chem. 1990, 55, 5033; (https://pubs.acs.org/doi/10.1021/jo00304a013).
26) Kowalski, M. H.; Hinkle, R. J.; Stang, P. J. "A Simple Highly Stereospecific Preparation of Vinylphosphonium Salts: Palladium-Catalyzed Vinylation of Triphenyl-phosphine via Vinyl Triflates" J. Org. Chem. 1989, 54, 2783; (https://pubs.acs.org/doi/10.1021/jo00273a003).
27) Pike, R. M.; Mayo, D. W.; Butcher, S. S.; Butcher, D. J.; Hinkle, R. J., "Microscale
Organic Laboratory IV: A Simple and Rapid Procedure for Carrying Out Wittig
Reactions" J. Chem. Ed. 1986, 63, 917.
†University of Alberta, Edmonton, Alberta, Canada
FELLOWSHIPS AND GRANTS
Contributions to Other William & Mary Grant Proposals
1) Beckman Scholars’ Program: Submitted on behalf of the College of William & Mary,
August 2014. Professor Margaret Saha, Development staff and I crafted the submitted document. This institutional grant was awarded for 2015-2018.
2) NSF MRI: "Acquisition-Upgrade of a 400 MHz Nuclear Magnetic Resonance Spectrometer to Facilitate Research and Improve Student Research and Education," Christopher Abelt as lead P.I. of this proposal. Submitted February 2013, Awarded.
3) NSF "Purchase of an NMR Spectrometer," Christopher Abelt as lead P.I. of this proposal. Submitted January 2012, Not funded.
4) Department of Energy (Manos and Cooke as P.I.s), “Sustainable Algal Production and
Environmental Remediation,” Appropriation for $625,000 for August 2010 to July
2011. Hinkle portion was $30K for analyses of algal degradation products and carbohydrate contents.
5) NSF "Purchase of an NMR Spectrometer," Christopher Abelt as lead P.I. of this proposal. Submitted June 2010, Not Funded.
6) StatoilHydro Proposal: WILLIAM AND MARY RESEARCH INSTITUTE (WMRI):
An Integrated Research Program for Algal Energy and Environmental Remediation. Total Budget = $2 Million; RJH portion in overall budget is $40,000 for analyses, equipment as well as PI and undergraduate student salaries Awarded, 2010.
7) StatoilHydro Proposal: WILLIAM AND MARY RESEARCH INSTITUTE (WMRI):
An Integrated Research Program for Algal Energy and Environmental Remediation. Total Budget = $1 Million; RJH portion in overall budget is $80,309 for analyses, equipment as well as PI and student salaries. Awarded, 2009.
8) NSF "Purchase of an X-ray Diffractometer," Robert D. Pike as lead investigator of this proposal submitted 25 June 2004. Awarded.
9) Howard Hughes Medical Institute grant (Margaret Saha, P.I.), 1998; Awarded
$88,353 (of ~ $1.5 million total) was to develop microscale and computational experiments for the Organic Chemistry laboratories. Joint project with former colleague, Kathleen M. Morgan (chemistry).
10) Pedagogical Grant Proposal, University Fellowship Funds of William and Mary,
“Modernization of Organic Chemistry Laboratory.” Kathleen Morgan with Robert J. Hinkle and Christopher J. Abelt as collaborators. Each awarded $800.00 stipends for development of laboratory exercises.
Individual and Co-Investigator Grant Proposals While at William & Mary
1) Douglas D. Young and Robert J. Hinkle, Commonwealth Health Research Board (VA), “Systematic Structure-Activity Relationships for Simplified
Polyynes,” Requested 151,900 for 6/1/2023-5/31/2025. Funded.
2) Robert M. Hinkle, National Institutes of Health AREA (R15), “Synthesis and Biological Assessment of a Polyyne Library” with Grants.gov
GRANT13742508; Requested $$428,091 ($300,000 Direct) for 6/1/2023 to 5/31/2026. Not Funded.
3) Robert J. Hinkle and Douglas D. Young, National Science Foundation, “Synthesis and Systematic Investigation of Polyyne Structure on Stability and Biological Activity,” Requesting $525,202 for 01 June 2022 to 31 May 2025. – Submitted, 30 September 2021. Not Funded.
4) Robert J. Hinkle and Douglas D. Young, National Science Foundation, “Synthesis and Biological Assessment of a Polyyne Library via Glaser-Hay Reactions,” Requesting $513,056 for 01 June 2021 to 31 May 2024. – Submitted, 15 October 2020. Not Funded.
5) Robert J. Hinkle and Douglas D. Young, National Science Foundation, “Combinatorial Synthesis of Novel Polyynes via Solid-Supported Glaser-Hay Reactions,” Requesting $572,124 for 01 September 2020 to 31 August 2023. – Submitted, 30 September 2019 – Not Funded.
6) National Science Foundation, “Aromatization Cascade Reactions: Applications of Alkynediols to Highly-Varied Aromatics,” Requesting $298,707 for 01 September 2019 to 31 August 2022. – Submitted, 01 October 2018 – Not Funded
7) National Science Foundation, “Development of Alkynediols as Versatile Substrates for Cyclization and Aromatization Reactions,” Requesting ~$339,457 for 01 September 2018 to 31 August 2021. – Submitted, 02 October 2017 – Not Funded
3) National Science Foundation, “Stereoselective Additions and Polycylic Cascades via Oxocarbenium Ions,” Requested $337,133 for 01 September 2017 to 31 August 2020 – Not Funded.
4) National Science Foundation, “Carbenium Ion Methodology: Stereoselective Additions and Polycyclization Cascades,” Requested $383,418 for 01 September 2015 to 31 August 2018 – Not Funded.
5) Petroleum Research Fund of the ACS, “Alkynyl-Prins Cascade Sequences: Understanding Regio- and Stereoselectivity and Application to Extended Aromatic Compounds,” Requested $70,000 for 01 June 2015 to 31 May 2018 — Not Funded.
6) National Science Foundation, “Cyclic Oxocarbenium Iions: Stereoselectivity of Additions and Development of an Alkynyl-Prins Cascade.,” Requested $379,280
7) National Institutes of Health, AREA (R15), “Alkynyl-Prins Cascade to Tricyclic Heterocycles: Studies of the Mechanism and Scope,” Requested $355,252 for 01 May 2014 to 31 April 2017— Not Funded.
8) National Institutes of Health, AREA (R15) RENEWAL of Proposal 4 below. “Bi(III)- Initiated Chemistry: Mechanistic Investigations of Catalytic Activity,” Requested $324,302 for 01 May 2011 to 31 April 2014—Not Funded.
9) National Science Foundation, “Tuning Oxocarbenium Ion and Acyl Iminium Ion Reactivity and Stereoelectronics,” Requested $340,622 for 6/1/2010 to
5/31/2013, Awarded $239,000 for 01 September 2010 to 30 August 2013.
10) National Institutes of Health, AREA, “Bi(III)-Initiated Chemistry: Mechanistic Investigations of Catalytic Activity,” Awarded $212,092 for 01 May 2007 to
31 April 2011.
11) Research Corporation, “Bi(III)-Catalyzed Tandem Addition and Silyl-Prins Cyclization Reaction Mechanisms,” Submitted 19 November 2006 for $33,589 for two years; RECOMMENDED FOR FUNDING, BUT WITHDRAWN DUE TO NIH AWARD ABOVE (item 10).
12) Henry Dreyfus Teacher-Scholar Award, $60,000, October 2002 to October 2007.
13) Thomas F. and Kate Miller Jeffress Memorial Trust, “Establishing the Role of Catalytic Quantities of Bi(III) Reagents in Organic Transformations, ”Submitted 01 September 2006—withdrawn due to remaining funding in previous Jeffress Award.
14) National Science Foundation, “Bi(III)-Initiated Chemistry: Stereoselectivity Studies and Silyl-Prins Reactions,” Submitted 15 January 2006 for $301,192 for a period of three years. Not Reviewed because of significant overlap with pending NIH award (#10 above).
15) Research Corporation, “Bi(III)-Catalyzed Tandem Addition and Silyl-Prins Cyclization Reactions,” Submitted 21 November 2005 for $35,127 for two years. Not Funded.
16) National Institutes of Health, AREA, “Bi(III)-Initiated Chemistry: Stereoselectivity Studies & Silyl-Prins Reactions," Submitted 25 September 2005 for $150,000 for a three year period. Not Funded.
17) Petroleum Research Fund of the American Chemical Society, “Bi(III) Complexes: Inexpensive, Environmentally-Friendly Achiral and Chiral Bi(III) Reagents for Asymmetric Allylation and Mukaiyama Aldol Reactions.” Submitted 15 September 2005 for $50,000 for three year period. Not Funded.
18) National Institutes of Health, AREA: Developing Bi(III)-Initiated Oxocarbenium Reactions," Submitted 25 January 2004 for $150,000. Not funded.
19) National Science Foundation, CAREER Award, “Alkenyl(aryl)iodanes: Investigations of Reactivity and New Syntheses.” Submitted on 7/22/99 and Awarded $294,810 for 01 March, 2000 to 29 February, 2004. No-cost Extension approved through 2005.
20) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Robert J. Hinkle and David E. Kranbuehl as co-investigators. Awarded $118,603 for September 1999 to August 2003.
21) Jeffress Memorial Trust, “Expanding the Scope of Alkenyl(aryl)-iodonium Substitutions,” Requested $15,873. Renewal submitted 01 March, 1999. Awarded $15,000. Award including initial grant (14 below) totals $29,952.
22) Research Corporation, "Solvolysis of Electron-Deficient Alkenyl(aryl)iodonium Salts via Vinyl Cations,” Requested $32,319. Submitted 14 November 1997. Awarded $32,319, June 1998.
23) William and Mary Summer Grant; Summer 1998, "Synthesis and Solvolysis of Electron-deficient Alkenyl(aryl)iodonium Triflates." Awarded $5000. I declined award because of acceptance of proposal 22 above.
24) Jeffress Memorial Trust, “Expanding the Scope of Alkenyl(aryl)iodonium Substitutions,” Requested $15,873. Submitted 30 August 1997. Awarded $14,952.
25) Research Corporation, "The Synthesis and Solvolysis of Electron-Deficient Alkenyl(aryl)iodonium Salts." Requested $29,658. Submitted 10/20/96. Not funded.
26) Jeffress Memorial Trust, "The Influence of Substituents on Iodonium Ylide Stability and Reactivity," Requested $18,373. Submitted 2/28/97. Not funded.
27) Petroleum Research Fund of the ACS, "Investigations of Titanium Aryloxy Complexes as Carbocyclization Pre-Catalysts." Requested $20,000. Submitted 12/7/96. Awarded $20,000 for 01 September 1997 to 31 August 1999. No cost extensions granted through 8/02.
28) William and Mary Summer Grant; Summer 1997, "Electrophilic Modification of Coordinated Ligands." Awarded $5250.
29) NIH Postdoctoral National Research Service Award recipient; September 1993. Awarded $46,200 for stipends and institutional allowance.
30) Stauffer–Rozelle Fellowship, University of Utah; September 1987.
31) Surdna Foundation Fellowship, Bowdoin College; September 1985 to May 1986.
RESEARCH
Provisional Patent Applications Filed.
1) Tricyclic Benzo[f]isochromene compositions of matter, Robert J. Hinkle, Provisional Patent Application 62/714,155 filed 8/3/2018.
2) Hinkle, Robert J. “Polysubstituted Tetrahydropyran Compositions,” Application draft written, but not submitted.
3) Hinkle, Robert J. “Naphthyl(aryl)iodonium Salt Compositions from Electrophilic
Cyclizations,” Application draft begun, but not submitted.
4) Hinkle, Robert J. “Trisubstituted Tetrahydropyran Compositions,” Application
61/719,992. Filed 18 October 2012—Full application abandoned due to insufficient
biological activity in Eli Lilly screens.
5) Hinkle, Robert J. and Lewis, Shane E.,”Substituted Benzopyran Compositions,” Application 61/715,433. Filed 30 October 2012—Full application abandoned due to insufficient biological activity in Eli Lilly screens.
Non-Scientific Articles Highlighting Research:
McClain, J., “Bismuth Summer: Undergraduates Receive Funding for Pharmaceutical Research,” Ideation, 06 September 2006. Accessed 12.10.07: http://www.wm.edu/as/ideation/Fall2006.php?fetchid=7884
Sakai, J., “Let’s Hit the Chemistry Lab,” The Richmond Times Dispatch, 13 August 2006. Accessed 12/10/07: http://www.jillsakai.com/Writing/Samples/Richmond/pdfs/081306- chem.pdf
Invited Scholarly Papers and Talks (presenter in bold, undergraduates underlined):
1) Robert J. Hinkle, Limitations of Tandem Cyclization-Additions to Oxocarbenium Ions and Development of a Cascade Sequence to Novel Tricycles, Old Dominion University,14 November 2013
2) Robert J. Hinkle, Cyclizations Involving Oxocarbenium Ions: Limitations of Tandem Cyclization-Additions and Development of a Cascade Sequence to Novel Tricycles, The University of Utah, 03 October 2013
3) Robert J. Hinkle, Non-Toxic Bi(III) Compounds in Multicomponent Methods Toward
Cyclic Ethers,” The University of Delaware, 27 October 2011
4) Robert J. Hinkle, “Non-Toxic Bi(III) Compounds in Multicomponent Methods Toward
Cyclic Ethers,” Western Michigan University, 25 September 2011.
5) Robert J. Hinkle, Environmentally-Friendly, Bi(III)-Initiated Multicomponent MethodsTowards Cyclic Ethers," Colby College, Waterville, ME, 23 April 2010.
6) Robert J. Hinkle, “Non-Toxic Bi(III)-Initiated Multicomponent Methods TowardCyclic Ethers,” University of Michigan, Ann Arbor, MI, 06 April 2010.
7) Robert J. Hinkle, “Environmentally-Friendly, Bi(III)-Initiated Multicomponent Methods Towards Cyclic Ethers." The University of Richmond, Richmond, VA, 15 January 2010.
8) Robert J. Hinkle, 2008 NSF Workshop on Organic Synthesis and Natural Products Chemistry, June 19-22, 2008. The Minary Center Holderness, NH. I was the only undergraduate faculty member invited to this prestigious workshop.
9) Robert J. Hinkle,* Kristie M. Schmidt, Yajing Lian, and Heather E. Stevenson, “One-
Pot, Three-Component Mukaiyama Aldol/Silyl-Prins Reactions to Dihydropyrans,”
Gordon Research Conference: Organic Reactions and Processes, Smithfield, RI, 15-20 July 2007, Invited Oral Presentation based on Poster Award, Thursday, 20 July 2007.
10) Robert J. Hinkle, “Stereoselective Bi(III)-Mediated Two- and Three-Component Addition-Silyl-Prins Reactions to 2,6-Disubstituted Dihydropyrans,” Invited speaker for Maryland Symposium on Research at Undergraduate Institutions, University of Maryland, College Park, MD, 19 October 2007.
11) Robert J. Hinkle, “Bi(III) Compounds in Sakurai Allylations and Mukaiyama Aldol Reactions: Catalysts or Pre-Catalysts?” Old Dominion University, Norfolk, VA, 11 November 2005.
12) Robert J. Hinkle, “Alkenyl(aryl)iodonium Reactivity and Cyclic Ether Syntheses.” Brown University,Providence, RI, 24 October 2004.
13) Robert J. Hinkle, “Alkenyl(aryl)iodonium Reactivity and Tetrahydropyran Syntheses.” Bowdoin College, Brunswick, ME, 25 April 2003.
14) Robert J. Hinkle, "Alkenyl(aryl)iodonium Salts: Substitution and Fragmentation
Reactions in Solution." The University of Delaware, Wilmington, Delaware, 30 August
2000.
15) Robert J. Hinkle, “Fragmentations and Substitutions of Alkenyl(aryl)iodonium Triflates.” The University of Alberta, Edmonton Canada, 11 June 1999.
REVIEWS OF BOOKS, SOFTWARE, ETC.:
Proposals Reviewed for the following agencies:
Beckman Scholars’ Program Advisory Committee -- Dates and details confidential
American Chemical Society National Award Selection Panel – Dates and
Details confidential
Jeffress Memorial Trust of Virginia
Research Corporation, Cottrell Scholars Program
American Chemical Society (ACS)
ACS, PRF, Type B
ACS, PRF-GB
ACS, PRF_UNI
NSF, RUI
NSF CHE
NSF Special emphasis Panel
NSF Int. Western Europe Program
NSF Major Research Instrumentation (MRI)
US Civilian Research and Development Foundation (CRDF)
External Tenure/Promotion Cases Reviewed:
Six --details confidential
External Promotion Cases Reviewed:
Two --details confidential
Articles reviewed:
Typically reviewed at least four manuscripts per year and have reviewed papers for the following journals:
Organic Letters
Chem. Soc. Reviews.
Advanced Synthesis and Catalysis
Journal of Organic Chemistry
Journal of the American Chemical Society Organic and Biomolecular Chemistry Chemistry -- A European Journal
European Journal of Organic Chemistry
Synthesis Arkivok Tetrahedron
Tetrahedron Letters
J. Phys. Org. Chemistry Chemical Communications Beilstein
Hinkle’s Oral and Poster Presentations at Regional or National Professional Meetings (Not Listed Among Publications Above; Presenter in bold, W&M undergraduates underlined):
1) Hinkle, Robert J.; Burns, Caleb. M.; McFadden, Kevin M.; Kim, Katherine U. “Alkyne-Prins reaction toward rapid and efficient construction of helical, polycyclic ethers,” National Meeting of the American Chemical Society, Denver, CO, United States, August 18-22 (2024), ORGN 4108511, Oral Presentation.
2) Hinkle, Robert J.; Burns, Caleb. M.; McFadden, Kevin M.; Kim, Katherine U. Kim. “Application of alkynyl-Prins reactions: Atom-economical cascade sequence to fused, tetracyclic dihydrochromeno[3,4-c]chromenes,” Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, United States, October 25-28 (2023), Oral Presentation.
3) Hinkle, Robert J. ,Caleb L. Burns, Kevin M. McFadden, Katherine U. Kim, Brendon Carnell, Tituoan Dustin, and Nathanael Kidwell,* “Alkyne-Prins Reaction Toward Rapid Construction of Polycyclic Ethers,” Gordon Research Conference on Organic Reactions and Processes, July 17-22, 2024. Poster Presentation.
4) Hinkle, Robert J., Caleb L. Burns, Kevin M. McFadden, Katherine U. Kim, “Alkyne-Prins Reaction Toward Rapid Construction of Polycyclic Ethers,” Gordon Research Conference on Organic Reactions and Processes, July 16-21, 2023. Poster Presentation.
5) Hinkle, Robert J.,* Caleb E. Burns, Kevin M. McFadden, Brendon Carnell, and Kate M. Burns, Tituoan Dustin, Nathanael Kidwell,* “Rapid Synthesis of Polycyclics using Alkyne-Prins Cascade Reactions,” Organic Reactions and Processes Gordon Conference, Poster Presentation, 17-19 July 2022.
6) Hinkle, Robert J.,* Yuzhou Chen, Colleen Nofi, Sarah Bredenkamp, Seong Ik Cheon, and Shane E. Lewis, “1-Aryl-3-alkyne-2,6-diols: Precursors for Electrophilic Cascade Reactions to Naphthyliodonium salts and Benzo[f]isochromenes,” Poster Presentation M-13, 23 June 2019.
7) Hinkle, Robert J.;* Chen, Yuzhou; Nofi, C. P.; Lewis, S. D., “Electronic effects in domino reactions toward tricyclic 1,4-dihydro-2H-benzo[f]isochromenes: Concerted alkynyl-Prins and Friedel-Crafts reactions” 254th National Meeting of the American Chemical Society, Washington, DC, United States, August 20-24 (2017), ORGN 102. Oral Presentation.
8) Hinkle, Robert J.,* Sarah Bredenkamp, Seong Ik Cheon, Yuzhou Chen, Colleen P.
Nofi and Shane E. Lewis,” Gordon Conference on Physical Organic Chemistry, Holderness, NH, 25-29 June 2017. Poster Presentation.
9) Hinkle, Robert J. Yuzhou Chen, Colleen P. Nofi, and Shane E. Lewis, “Novel Aromatization Cascade Toward Fused Hetercycles,” Gordon Conference on Organic Reactions and Processes, Easton, MA, 13-18 July 2016. Poster Presentation.
10) Hinkle, Robert J., Yuzhou Chen, Colleen P. Nofi and Shane E. Lewis, “Novel Cyclization-Aromatization Cascade to Benzo[f]isochromenes” Gordon Conference on Organic Reactions and Processes, Smithfield, RI, 14-19 July 2015. Poster Presentation
11) Hinkle, Robert J. Yuzhou Chen, Colleen P. Nofi and Shane E. Lewis, “Four-Reaction Cascade Toward 2,2,4-Trisubstituted-2,4-Dihydro-1H-Benzo[f]isochromenes: Chiral Enantioselective Synthesis of a Disubstituted Core” Gordon Conference on Organic Reactions and Processes, Smithfield, RI, 13-18 July 2014. Poster Presentation.
12) Hinkle, Robert J. and Lewis, Shane E. “Two-Component, Four-Reaction Cascade Toward 2,2,4-Trisubstituted-2,4-Dihydro-1H-Benzo[f]isochromenes,” Gordon Conference on Organic Reactions and Processes, Smithfield, RI, 14-19 July 2013. Poster Presentation.
13) Hinkle, Robert J.;* Rahman, Ajara A.; Lambert, R. F.; Ammann, Stephen E.; Willard, Emily G.; Merryman, Caroline P., “Cyclization-addition reactions toward trisubstituted tetrahydropyrans: Effects of sterics and electronics on cyclization,” 64th Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, United States, November 14-17 (2012), SERM-437.
14) Hinkle, Robert J.;* Rahman, Ajara A.; Salvant, Justin M.; Willard, Emily G., “Effects of electron-donating and withdrawing substituents on the stereochemical outcome of cyclization-addition reactions toward trisubstituted tetrahydropyrans,” 244th ACS National Meeting & Exposition, Philadelphia, PA, United States, August 19-23, 2012 (2012), Abstract ORGN-431, Oral Presentation.
15) Hinkle, Robert J.;* Rahman, Ajara A.; Lewis, Shane E.; Lambert, R. Frederick; and Ammann, Stephen E. “Di- and Trisubstituted Tetrahydropyrans and Oxepanes via Cyclic Oxocarbenium Ions. Gordon Conference on Heterocyclic Compounds, Newport, RI, 24-29 June 2012. Poster Presentation.
16) Hinkle, Robert J.;* Rahman, Ajara A.; Lambert, R. F.; Ammann, Stephen E.; Willard, Emily G.; Merryman, Caroline P., “Cyclization-addition reactions toward trisubstituted tetrahydropyrans: Effects of Sterics and Electronics on Cyclization,”64th Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, United States, November 14-17 (2012), Abstract SERM-437. Oral Presentation.
17) Hinkle, Robert J., “Bi(OTf)3-Mediated epoxide rearrangement and intramolecular silyl modified Sakurai reaction (ISMS) to dihydropyrans: Establishing the role of Bi(OTf)3,” Southeast Regional Meeting of the American Chemical Society (SERMACS), Richmond, VA, Oct. 26-29, 2011. Abstract SERM 887.
18) Hinkle, Robert J.; Lambert, R. Frederick; Ammann, Stephen E.; Lewis, Shane E.; Liu, Jia; Lian, Yajing, “Bi(OTf)3-Mediated epoxide rearrangement and intramolecular silyl-modified Sakurai reaction (ISMS) to dihydropyrans: Establishing the role of Bi(OTf)3,” 63rd Southeast Regional Meeting of the American Chemical Society, Richmond, VA, October 26-29,2011, SERM-204, Oral Presentation.
19) Hinkle, Robert J. “Bi(OTf)3 Initiated Epoxide Rearrangement and ISMS ReactionsToward Dihydropyrans: Role of Bi(OTf)3?” Gordon Research Conference, July 18-24 2010. Poster Presentation.
20) Hinkle, Robert J.; Lian, Yajing; Speight, Lee C.; Liu, Jia; Ammann, Stephen; Lambert, Frederick, “Bi(III)-Mediated Epoxide Rearrangement and Intramolecular Silyl- Modified Sakurai Reaction (ISMS) to Dihydropyrans,” Presented at the 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009, Abstract ORGN-428. Poster Presentation.
21) Hinkle, Robert J.; Lambert, Robert F.; Ammann, Stephen E.; Speight, Lee C.; Liu, Jia; Lian, Yajing, “Bismuth-initiated reactions toward stereoselective syntheses of tetrahydropyrans and dihydropyrans ,” Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010 (2010), Abstract ORGN-461.
22) Hinkle, Robert J.; Lian, Yajing; Speight, Lee C.; Liu, Jia; Ammann, Stephen; Lambert, Frederick, “Bi(III)-mediated expoxide rearrangement and intramolecular silyl-modified Sakurai reaction (ISMS) to dihydropyrans,” 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009, Abstract ORGN-428.
23) Hinkle, Robert J.; Lian, Yajing; Speight, Lee C.; Liu, Jia; Ammann, Stephen; Lambert, Frederick, “Bi(III)-Mediated Epoxide Rearrangement and Intramolecular Silyl- Modified Sakurai Reaction (ISMS) to Dihydropyrans,” Presented at the 238th ACS National Meeting, Washington, DC, United States, August 16-20, 2009, Abstract ORGN-428.
24) Hinkle, Robert J.; Schmidt, Kristie M.; H.Lian, Yajing, Stevenson, Heather E.; Johnson, Danielle H.; Forgues; Christine, “One-Pot, Three-Component Mukaiyama Aldol/Silyl-Prins Reactions to Dihydropyrans,” Presented at the National Organic Symposium (NOS), Duke University, Durham, NC, June 3-7, 2007, Abstract B36.
25) Hinkle, Robert J.* Schmidt, Kristie M.; Lian, Yajing; and Stevenson, Heather E. “One-Pot, Three-Component Mukaiyama Aldol/Silyl-Prins Reactions to Dihydropyrans,” Gordon Research Conference: Organic Reactions and Processes, Smithfield, RI, 15-20 July 2007, Invited Oral Presentation based on Poster Award, Thursday, 20 July 2007.
26) Hinkle, Robert J.* Schmidt, Kristie M.; Lian, Yajing; and Stevenson, Heather E. “One-Pot, Three-Component Mukaiyama Aldol/Silyl-Prins Reactions to Dihydropyrans,” Gordon Research Conference: Organic Reactions and Processes, Smithfield, RI, 15-20 July 2007. Poster Presentation.
27) Hinkle, Robert J.* Schmidt, Kristie M.; Lian, Yajing; and Stevenson, Heather E.; Johnson, H. Danielle; Forgues, Christine “One-Pot, Three-Component Mukaiyama Aldol/Silyl-Prins Reactions to Dihydropyrans,” Presented at the 39th National Organic Symposium, Durham, NC, June 3-7, 2007. Poster Presentation B36.
28) Hinkle, Robert J.* Schmidt, Kristie M.; Lian, Yajing; and Stevenson, Heather E.; Johnson, H. Danielle; “Bi(III)-Initiated Two- and Three-component Addition/silyl-Prins Reactions Toward cis-2,6-Disubstituted Dihydropyrans,” Presented at the 58th Southeastern Regional Meeting of the American Chemical Society, Augusta, GA, November 01-04, 2006. Oral Presentation 227.
29) Hinkle, Robert J.,* Yajing Lian, Kristie Schmidt, Heather Stevenson, H. Danielle Johnson, “Bi(III)-Initiated Two- and Three-component Addition/silyl-Prins Reactions Toward cis-2,6-Disubstituted Dihydropyrans,” Presented at the 58th Southeast Regional Meeting of the American Chemical Society (SERMACS), November 1-4,2006. Abstract 227.
30) Hinkle, Robert J.,* Yajing Lian, Kristie Schmidt, Heather Stevenson, H. Danielle Johnson, “Bi(III)-Initiated Two- and Three-component Addition/silyl-Prins Reactions Toward cis-2,6-Disubstituted Dihydropyrans,” Presented at the 58th Southeast Regional Meeting of the American Chemical Society (SERMACS), November 1-4, 2006. Abstract 227.
31) Robert J. Hinkle, Yajing Lian, Nichole D. Litvinas, Alexander T. Jenkins, Danielle C. Burnette, "BiBr3 Initiated Cyclization-Addition Reactions: Total Synthesis of (+)-(S,S)-(cis-6-Methyltetrahydropyran-2-yl)acetic Acid, its trans-Diastereomer and Effect of Nucleophile on Oxocarbenium Ion Additions, Presented at the National Organic Symposium (NOS), Salt Lake City, Utah, June 12-16, 2005. Abstract B21.
32) Hinkle, Robert J., Yajing Lian, Mamio C. Mattern and Melissa M. Sprachman, “Bismuth(III) Initiated Diastereoselective Cyclization-Addition Reactions Toward 2,6- Disubstituted Tetrahydropyrans,” Presented at the 230th National Meeting of the American Chemical Society, August 31, 2005; Washington, DC. Abstract ORGN-538.
33) Hinkle, Robert J.; Lian, Y.; Litvinas, N. D.; Jenkins, A. T.; Burnette, D. C. " BiBr3-Initiated Cyclization-Addition Reactions: Total Synthesis of (+)-(S,S)-(cis-6- Methyltetrahydropyran-2-yl)acetic Acid, its trans-Diastereomer and Effect of Nucleophile on Oxocarbenium Ion Additions, Presented at the National Organic Symposium, Salt Lake City, Utah, June 12-16, 2005. Poster Presentation B21.
34) Hinkle, Robert J.,* Yajing Lian, Kristie Schmidt, Heather Stevenson, and H. Danielle Johnson, “Bi(III)-Initiated Two- and Three-component Addition/silyl-Prins Reactions Toward cis-2,6-Disubstituted Dihydropyrans,” Presented at the 58th Southeastern Regional Meeting of the American Chemical Society (SERMACS), Durham, NC, November 01-04, 2004. Abstract 227.
35) Hinkle, Robert J.; Mattern, M. C.; Sprachman, M. M.; and Litvinas; N. D., "Bismuth(III) Initiated Diastereoselective Cyclization-Addition Reactions Toward 2,6-Disubstituted Tetrahydropyrans," Presented at the 56th Southeastern Regional Meeting of the American Chemical Society (SERMACS), Durham, NC, November 10-13, 2004. Abstract 200.
36)
Hinkle, R. J.; Evans, P. A.; Cui, J.; Delouvrie, B. D., “Diastereoselective Syntheses of Di- and Trisubstituted Cyclic Ethers via Tandem Cyclization-Addition Reactions,” Presented at the 225th American Chemical Society Meeting, New Orleans, LA, March 23-27, 2003. Abstract ORGN-666.
37) Hinkle, R. J.; Mikowski, A. M. "Fragmentation Reactions of Alkenyl(aryl)iodonium Tiflates Salts." Presented at the 223rd American Chemical Society Meeting, Orlando, Fl, April 06-11, 2002. Poster Presentation 332.
38) Hinkle, R. J.; Rouse, E. A.; McNeil, A. M.; Thomas, Q. A.; Thomas, D. B. "Vinyl Cations from Alkenyl(aryl)iodonium Salts: Are Primary Vinyl Cations involved?" Presented at the 221st American Chemical Society Meeting, San Diego,CA, April 01-05, 2001. Abstract 450.
39) Hinkle, R. J.; Rouse, E. A.; McNeil, A. J. "Fragmentation of Alkenyl(aryl)iodonium Triflates via Vinyl Cations," Presented at the 220th American Chemical Society Meeting, Washington, DC, August 30, 2000. Abstract 295.
40) Hinkle, R. J.; Leri, A. C.; David, G. A.; Erwin, W. M. "Addition of Benzylzinc Halides to Alkenyl(phenyl)iodonium Triflates: Stereoselective Synthesis of Trisubstituted Alkenes," Presented at the 219th American Chemical Society Meeting, Newsletter and Abstracts, March 26-30, 2000. Abstract 535.
41) Hinkle, R. J.; Aubry, Q. D.; McNeil, A. J.; presented at the 216th National American Chemical Society Meeting, Boston, MA, August 23-27, 1998; Poster Presentation, 240.
42) Hinkle, R. J.; Aubry, Q. D.; McNeil, A. J. “Synthesis and Decomposition of Alkenyl(aryl)iodonium Triflates via Vinyl Cations.” Presented at the 216th American Chemical Society Meeting, Newsletter and Abstracts, 1998. Abstract 640, Oral Presentation.
43) Hinkle, R. J.; Thomas, D. B. “Generation of Primary Vinyl Cations from Alkeny(aryl)iodonium Triflates, presenting at 49th ACS Southeast Regional Meeting, Roanoke VA, October 19-22, 1997; Poster Presentation.
44) Hinkle, R. J.; Stang, P. J.; Arif, A. M. "Novel Formation of Platinaoxacycllic Compounds and Heck Coupling Product via Reaction of (s-2-propenyl)(PPh3)2Pt(II) Triflate with Acrylate Esters," presented at 205th National ACS Meeting, Denver, CO, March/April, 1993; included in special "Sci-Mix" session; Poster Presentation, 056
45) Hinkle, R. J.; Zhong, Z.; Stang, P. J., " s -Metal Triflates: The Reaction of (s-vinyl) Platinum(II) Triflates with Acrylates," presented at 16th NSF Organometallic Workshop, Snowbird, Utah, May, 1992; Poster Presentation.
Presentations to which I contributed from undergraduate years at Bowdoin College.
1) Mayo, D. W.; Butcher, S. S.; Hinkle, R. J.; Bartlett, L. G.; Sewall, C. J.; Hirth, B. H.; Pike, R. M.; †Ryan, J.; †Riley, L., "A High Resolution Short Path Microscale Distillation Column: The Hickman-Hinkle Still," presented at Pittsburg Conference, Atlanta, GA, March, 1989; Abstract 967. †Ace® Glass Company.
2) Mayo, D. W.; Hinkle, R. J.; Butcher, S. S.; Pike, R. M.; †Ryan, J., "A Simple, HighlyEfficient Spinning Band Microdistillation Column," presented at Pittsburg Conference, Atlantic City, NJ, February, 1987; Abstract 089. †Ace® Glass Company.
Research Reports for Grants.
1) Commonwealth Health Resources Board (CHRB) of Virginia, Financial Report, July 2025.
2) Commonwealth Health Resources Board (CHRB) of Virginia, Financial Report, March 2025.
3) Commonwealth Health Resources Board (CHRB) of Virginia, Financial Report, July 2024.
4) Commonwealth Health Resources Board (CHRB) of Virginia, Scientific Report, March 2024.
5) National Science Foundation Final Report, December 2015.
6) National Science Foundation Annual Report, August 2014.
7) National Science Foundation Annual Report, July 2013.
8) DOE Interim Progress Report, October 2012.
9) DOE Interim Progress Report, August 2012.
10) National Science Foundation Annual Report, July 2012.
11) DOE Interim Progress Report, May 2012.
12) DOE Interim Progress Report, February 2012.
13) DOE Interim Reports, September, December, 2011.
14) Statoil Final Report, August 2011.
15) National Science Foundation Annual Report, July 2011.
16) Statoil Interim Report II, September 2010.
17) Statoil Interim Report I, filed March 2010.
18) National Institutes of Health, USA, filed June 2011.
19) National Institutes of Health, USA, filed May 2010.
20) National Institutes of Health, USA, filed June 2009.
21) Jeffress Memorial Trust, Final Report, filed March 2008.
22) Henry-Dreyfus Teacher-Scholar Award, Final Report, filed 15 December 2007.
23) Jeffress Memorial Trust, Interim Report, filed 24 January 2007.
24) Jeffress Memorial Trust, Interim Report, filed 22 December 2005.
25) National Science Foundation, CAREER Award, Final Report, filed 19 May 2007.
26) Henry Dreyfus Teacher-Scholar Award, 2nd year report. Submitted 05 December 2004.
27) Investigations of Titanium Aryloxy Complexes as Carbocyclization Pre-Catalysts. PRF, Sept 2001.
28) Petroleum Research Fund (PRF) of the American Chemical Society. Submitted 28 September 2002.
29) Research Corporation, "Solvolysis of Electron-Deficient Alkenyl(aryl)iodonium Salts via Vinyl Cations.” Submitted June 2002.
30) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted September 2002.
31) Jeffress Memorial Trust, “Expanding the Scope of Alkenyl(aryl)iodonium Substitutions." Submitted June 2002.
32) Investigations of Titanium Aryloxy Complexes as Carbocyclization Pre- Catalysts.Petroleum Research Fund (PRF) of the American Chemical Society. Submitted 28 September 2001.
33) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted March 2002.
34) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted February 2002.
35) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted September 2001.
36) Research Corporation, "Solvolysis of Electron-Deficient Alkenyl(aryl)iodonium Saltsvia Vinyl Cations.” Submitted 28 June 2002.
37) Jeffress Memorial Trust, “Expanding the Scope of Alkenyl(aryl)iodonium Substitutions." Submitted 28 June 2001.
38) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted May 2001.
39) NSF CAREER Award, "Alkenyl(aryl)iodanes: Investigations of Reactivity and New Syntheses," Submitted 01 May 2001
40) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted February 2001.
41) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted April 2001.
42) Research Corporation, "Solvolysis of Electron-Deficient Alkenyl(aryl)iodonium Salts via Vinyl Cations.” Submitted 28 June 2000.
43) Jeffress Memorial Trust, “Expanding the Scope of Alkenyl(aryl)iodoniumSubstitutions." Submitted 28 June 2000.
44) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted 15 December 1999.
45) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted 15 November 1999.
46) Coatings Technology, Ltd, “Understanding the Role of Diffusion and pH on a Color Indicator.” Submitted 15 December 1999.
47) Investigations of Titanium Aryloxy Complexes as Carbocyclization Pre-Catalysts. Petroleum Research Fund (PRF) of the American Chemical Society. Submitted 28 September 1999.
48) Research Corporation, "Solvolysis of Electron-Deficient Alkenyl(aryl)iodonium Salts via Vinyl Cations.” Submitted 28 June 1999.
49) Investigations of Titanium Aryloxy Complexes as Carbocyclization Pre-Catalysts. Petroleum Research Fund (PRF) of the American Chemical Society. Submitted 29 September 1998.
50) "Bis-Heck Cyclization Approach to the Growth Hormone Stimulant Psycholeine." NIH Fellowship progress report and continuation application. Submitted 11 Nov. 1994.
Student Posters and presentations to which I contributed (presenter(s) in bold font, undergraduate students underlined):
1) Olivia Molz, "Determination of the Antimicrobial Activity of Diynes Containing a Homopropargylic Ester," Fall William & Mary Undergraduate Research Symposium, 19 September 2025, Poster Presentation.
2) Gunnar Ternstrom, "Cascade Alkyne-Aza-Prins Reactions to Access Ergot Bioisosteres,” Fall William & Mary Undergraduate Research Symposium, 19 September 2025, Poster Presentation.
3) Katie A. Agamaite [Douglas D. Young, Robert J. Hinkle as co-P.I.s], “New Age Antibiotics: Creating Short-Chain Secondary Diols for Biological Testing,” Fall Undergraduate Research Symposium, 20 September 2024, Poster I3.
4) Tyler Skeen, [Douglas D. Young, Robert J. Hinkle as co-P.I.s] “Exploring Biofilm Disruptive Properties of Polyynes,” Fall Undergraduate Research Symposium, 20 September 2024, Poster D4.
5) Brendon B. Carnell, Robert J. Hinkle, Youzhou Chen, Colleen P. Nofi, Shane E. Lewis, Daniel J. Speer and Bethany L. Kanter, “Novel Aromatization Domino Sequence to Fused Heterocycles.” Poster Presentation W-9, 26 June 2019.
6) Lauren E. Mazur, Christopher R. Travis, Emily M. Peairs, Gillian H. Gaunt, Douglas D. Young,* Robert J. Hinkle,* “Mechanistic Investigation into the Biological Glaser-Hay Reaction,” Poster Presentation T-25, 25 June 2019.
7) Lauren E. Mazur, Christopher R. Travis, Emily M. Peairs, Gillian H. Gaunt, Douglas D. Young*, & Robert J. Hinkle, Mechanistic Investigation of the Biological Glaser-Hay Reaction, Beckman Scholars’ Symposium, Irvine California, August 1, 2019.
8) Brendon B. Carnell, Robert J. Hinkle*, Youzhou Chen, Colleen P. Nofi, Shane E. Lewis, Daniel J. Speer and Bethany L. Kanter, Novel Aromatization Domino Sequence to Fused Heterocycles, National Organic Symposium, June 2019.
9) Lauren E. Mazur, Christopher R. Travis, Emily M. Peairs, Gillian H. Gaunt, Douglas D. Young*, & Robert J. Hinkle, Mechanistic Investigation of the Biological Glaser-Hay Reaction, National Organic Symposium, June 2019.
10) Daniel J. Speer, Accessing Possible Cannabinoids Through an Alkynyl-Prins Cyclization, Oral Presentation at Honor’s Symposium, 2018.
11) Daniel J. Speer, “Accessing Possible Cannabinoids Through an Alkynyl-Prins Cyclization,” Poster at Undergraduate Research Symposium, 2018.
12) Sarah E. Bredenkamp, “Electrophilic Activation and Domino Reaction of Arylated Propargylic Alcohols Toward Naphthyl(aryl)iodonium salts,” Poster at Undergraduate Research Symposium, 2018
13) Bredenkamp, S. E.; Hinkle, R. J.;* Pike, R. D.; Cheon, S. I., “Electrophilic activation and domino reaction of arylated propargylic alcohols toward naphthyl(aryl)iodonium salts,” 254th National Meeting of the American Chemical Society, Washington, DC, United States, August 20-24 (2017), ORGN 612. Poster Presentation.
14) Cheon, Seong Ik, Hinkle, Robert J., “Alkynyl Aza-Prins Cyclization,” William & Mary Honors Colloquium, February 2017. Oral Presentation.
15) Shenouda, Hannah, Hinkle, Robert J. as advisor, “The Effect of Electron-Withdrawing Substituents on Bismuth-Catalyzed THP Formation,” William & Mary Undergraduate Science Research Symposium, April 21, 2015. Poster Presentation.
16) Lichstrahl, Michael, Hinkle, Robert J. as advisor, “The Stereoselective Synthesis of 1,3- Diols in the Natural Products Polyrhacitide A and B,” William & Mary Undergraduate Science Research Symposium, April 21, 2015. Poster Presentation.
17) Cooper, Jahan, Hinkle, Robert J. as advisor, “Developing Methodologies for the Stereo-Controlled Synthesis of Disubstituted Tetrahydropyrans and Applications Towards the Total Synthesis of Polyrhacitides,” William & Mary Undergraduate Science Research Symposium, April 21, 2015. Poster Presentation.
18) Perkins, Zack, Hinkle, Robert J. as advisor, “Synthesis of Alkylated Ketones For Future Bi Catalyzed Cyclic Ether Construction Through Oxocarbenium Intermediate,” William & Mary Undergraduate Science Research Symposium, April 21, 2015. Poster Presentation.
19) Shenouda, Hannah, Hinkle, Robert J. as advisor, “Investigations of Electron Withdrawing Substituents on the Selectivity of Nucleophilic Attack in Bismuth Catalyzed 2,6-disubstituted THP Formation,” William & Mary Summer Research Showcase, October 2, 2014. Poster Presentation.
20) Cooper, Jahan, Hinkle, Robert J. as advisor, “Progress Toward the Synthesis of Biologically Active Polyrhacitides,” William & Mary Undergraduate Science Research Symposium, February 28, 2014. Poster Presentation.
21) Butler, Mitchell, Hinkle, Robert J., “Efforts towards the Bi(III)-initiated Synthesis of Piperidines and Azepanes,” William & Mary Undergraduate Research Symposium, February 22 2013. Poster Presentation.
22) Merryman, Carline P.; Hinkle, R. J. “Synthesis and Reactivity of a Cyclic Six- Membered Oxocarbenium Ion Containing an Electron-Withdrawing Beta-Ester,” William & Mary Undergraduate Research Symposium, February 22, 2013. Poster Presentation.
23) Willard, Emily G.; Hinkle, Robert J. “Synthesis of Fluorine-containing Precursors to Cyclic Six-membered Oxocarbenium Ions and the Effects of Fluorine on Cyclization- addition Reactions,” William & Mary Undergraduate Research Symposium, February22, 2013. Poster Presentation.
24) Liu, Jeffrey; Hinkle, Robert J., “Investigation of BiBr3 Initiated Nucleophilic Additions to Seven-Membered Oxocarbenium Ions,” William & Mary Undergraduate Research Symposium, February 22, 2013. Poster Presentation.
25) Salvant, Justin M.; Hinkle, Robert J. “Steric Effects of Additions to Cyclic Six-Membered Oxocarbenium Ions, William & Mary Undergraduate Symposium, February 22, 2013. Poster Presentation.
26) Willard, Emily G.; Rahman, Ajara A.; Nofi, Coleen P.; Yeager, Benjamin M.; Hinkle, Robert J.,* “Synthesis of fluorine-containing precursors to cyclic six-membered oxocarbenium ions, and the effects of fluorine on cyclization-addition reactions,” 64th Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, United States (2012).
27) Salvant, Justin M.; Rahman, Ajara A.; Lambert, R. F.; Ammann, Stephen E.; Hinkle, Robert J.,* “Steric effects of additions to cyclic six-membered oxocarbenium ions,” 64th Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, United States, November 14-17 (2012), SERM-304. Poster Presentation.
28) Willard, Emily G.; Rahman, Ajara A.; Nofi, Coleen P.; Yeager, Benjamin M.; Hinkle, Robert J.* “Synthesis of Fluorine-Containing Precursors to Cyclic Six-Membered Oxocarbenium Ions, and the Effects of Fluorine on Cyclization-Addition reactions,”64th Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, United States, November 14-17 (2012), Abstract SERM-306. Poster Presentation.
29) Merryman, Caroline P. “Synthesis and Reactivity of a Cyclic Six-membered Oxocarbenium ion Containing an Electron-withdrawing b-Ester” Southeast Regional Meeting of the American Chemical Society, Raleigh, NC, United States, November 14-17 (2012), Abstract SERM-305. Poster Presentation.
30) Salvant, Justin M.; Willard, Emily G.; Rahman, Ajara A.; Hinkle, Robert J.,*“Cyclization-addition reactions toward trisubstituted tetrahydropyrans: Effects of substitution on electrophilic substrate and nucleophile,” 244th ACS National Meeting& Exposition, Philadelphia, PA, United States, August 19-23, 2012 (2012), Abstract ORGN-206. Poster Presentation.
31) Lewis, Shane E.; Hinkle, Robert J.* “Tandem addition/Prins/Friedel- Crafts/dehydration reactions towards 2,2,4-trisubstituted-2,4-dihydro-1H- benzo[f]isochromenes,” 244th ACS National Meeting & Exposition, Philadelphia, PA, United States, August 19-23, 2012 (2012), Abstract ORGN-205. Poster Presentation.
32) Lu, Xi; Hinkle, Robert J. “Synthesis of Six-Membered Oxocarbenium Rings,” William& Mary Undergraduate Symposium, 18 February 2012. Poster Presentation 42.
33) Rahman, Ajara, Hinkle, Robert J. “Effects of nucleophilic strength on facial selectivity in BiBr3 catalyzed tandem cyclization/addition reactions,” Southeast Regional Meeting of the American Chemical Society (SERMACS), Richmond, VA, Oct. 26-29, 2011. Abstract SERM-191.
34) Lewis, Shane E., Hinkle, R. J. “Tandem addition/Prins/Friedel-Crafts/dehydration reactions towards 2,2,4-trisubstituted-2,4-dihydro-1H-benzo[f]isochromenes,” Southeast Regional Meeting of the American Chemical Society (SERMACS), Richmond, VA, Oct. 26-29, 2011. Abstract SERM 98.
35) Hinkle, Robert J. “Bi(OTf)3–, TfOH–, and TMSOTf–Mediated, One-Pot Epoxide Rearrangement, Addition and Intramolecular Silyl-Modified Sakurai (ISMS) Cascade Toward Dihydropyrans: Comparison of Catalysts and Role of Bi(OTf)3,” Gordon Research Conference on Organic Reactions and Processes, July 2011. Poster Presentation
36) Lambert, R. Frederick, Hinkle, Robert J. “Bi(OTf)3–, TfOH–, and TMSOTf–Mediated, One-Pot Epoxide Rearrangement, Addition and Intramolecular Silyl-Modified Sakurai (ISMS) Cascade Toward Dihydropyrans: Comparison of Catalysts and Role of Bi(OTf)3, Beckman Scholars’ Symposium, Irvine, California, August 11-14, 2011. Poster Presentation.
37) Lewis, Shane E.; Hinkle, Robert J. “Tandem addition/Prins/Friedel-Crafts/Dehydration reactions toward 2,2,4,trisubstituted-2,4-dihydro-2H-benzo[f]isochromenes,” 63rd Southeast Regional Meeting of the American Chemical Society, Richmond, VA, United States, October 26-29, 2011, SERM-98 Poster Presentation.
38) Rahman, Ajara A.; Hinkle, Robert J.; Lambert, Robert F.; Ammann, Stephen E., “Effects of nucleophilic strength on facial selectivity in BiBr3 catalyzed tandem cyclization/addition reactions,” 63rd Southeast Regional Meeting of the American Chemical Society, Richmond, VA, United States, October 26-29, 2011, SERM-80 Poster Presentation.
39) Hinkle, Robert J., Lambert, R. Frederick, Ammann, Stephen E.; Lian, Yajing, Liu, Jia, “Bismuth-Initiated Reactions Toward Stereoselective Syntheses of Tetrahydropyrans and Dihydropyrans,” Presented at the 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010, Abstract ORGN-461, Oral Presentation.
40) Lambert, R. Frederick, Ammann, Stephen E.; Hinkle, Robert J.; Speight, Lee C.; Lian, Yajing, “Bismuth Salt-Initiated Epoxide Rearrangement and Addition Reactions Toward 2,6-Disubstituted Dihydropyrans: What is the Role of Bismuth?” Presented at the 240th ACS National Meeting, Boston, MA, United States, August 22-26,2010, Abstract ORGN-1037, Poster Presentation.
41) Speight, Lee C.; Hinkle, Robert J., Honors Research Symposium, February 2009, OralPresentation.
42) Ammann, Stephen E. ; Hinkle, Robert J.* “Bi(III)-Initiated Cyclization Reactions to2,6-Disubstituted 3,6-Dihydropyrans,” Undergraduate Research Symposium;February, 2009. Poster Presentation.
43) Brown, Timothy J.; Hinkle, Robert J.; Sprachman, Melissa M., “Diastereoselective Synthesis of 2,6-Disubstituted Tetrahydropyrans Using Catalytic BiBr3 and p-Nucleophiles,” Presented at the 58th Southeast Regional Meeting of the American Chemical Society (SERMACS), Augusta, GA, United States, November 1-4, 2006, Abstract SRM06-439.
44)
Brown, Timothy J.; Hinkle, Robert J.; Sprachman, Melissa M.; Mattern, Mamio C.; Yajing, Lian, “Investigations of p-Nucleophiles in the Synthesis of 2,6-Disubstituted Tetrahydropyrans,” Presented at the 38th Middle Atlantic Regional Meeting of the American Chemical Society, Hershey, PA, United States, June 4-7, 2006, Abstract MRM-329.
45) Katkish, Lauren A. ; Hinkle, Robert J.* “Toward Biologically-Active 2,6-Disubsti- tuted Dihydropyran Ring Systems,” Undergraduate Research Symposium; February,2008. Poster Presentation.
46) Speight, Lee C. , Hinkle, Robert J. “Three-Component Bi(III)-Initiated Tandem Reactions,” Robert J. Hinkle,* Undergraduate Research Symposium; February, 2008. Oral Presentation.
47) Brown, Timothy J.; Hinkle, Robert J.;* Sprachman, Melissa M.; Mattern, Mamio C.; Lian, Yajing “Investigations of p-Nucleophiles in the Synthesis of 2-6 Disubstituted Tetrahydropyrans,” Presented at the 58th Southeastern Regional Meeting of the American Chemical Society, Augusta, GA, November 01-04, 2006. Poster Presentation 439.
48) Brown, Timothy J.; Hinkle, Robert J.;* Sprachman, Melissa M.; Mattern, Mamio C.; Lian, Yajing, Investigations of p-nucleophiles in the synthesis of 2,6-disubstituted tetrahydropyrans. Abstracts, 38th Middle Atlantic Regional Meeting of the American Chemical Society, Hershey, PA, United States, June 4-7 (2006), Poster Presentation— withdrawn due to a death in Timothy Brown’s family.
49) Lian, Yajing; Hinkle, Robert J. “Etherification reactions initiated by BiBr3: TotalSynthesis of (+)-(S,S)-(cis-6-methyltetrahydropyran-2-yl)acetic Acid and its trans-Diastereomer,” 230th ACS National Meeting, 28 August to 01 September 2005, PosterPresentation 115.
50) Sprachman, M. M.; Hinkle, R. J.; “The Use of Bismuth Compounds in the Non-Toxic Syntheses of Natural Products,” Arnold and Mabel Beckman Scholars Symposium, Irvine, CA, July 2005. Poster Presentation.
51) Yajing Lian and Robert J. Hinkle*, “Etherification Reactions Initiated by BiBr3: Total Synthesis of (+)-(S,S)-(cis)-6-Methyltetrahydropyran-2-yl)acetic acid and its trans- Diastereomer,” Presented at the 230th National Meeting of the American Chemical Society, August 28 – 01 September, 2005; Washington, DC. Abstract ORGN-115.
52) Melissa M. Sprachman, Mamio C. Mattern, Yajing Lian and Robert J. Hinkle*, “Selective tandem cyclization-addition reactions using catalytic quantities of BiBr3 a nd π - nucleophiles,” Presented at the 230th National Meeting of the American Chemical Society, August 28 – 01 September, 2005; Washington, DC. Abstract ORGN-116.
53) Sprachman, Melissa M. “The Use of Bismuth Compounds in the Non-toxic Syntheses of Natural Products,” Beckman Scholars Symposium, July 2005.
54) Timothy J. Brown, Robert J. Hinkle,* Melissa M. Sprachman, Mamio C. Mattern, Yajing Lian, “Investigations of -Nucleophiles in the Synthesis of 2-6 Disubstituted Tetrahydropyrans,” Presented at the 58th Southeastern Regional Meeting of the American Chemical Society (SERMACS), Durham, NC, November 01-04, 2004. Abstract 439.
55) Lian, Yajing.; Hinkle, R. J.; Mikowski, A. M.; Brochu, M. C.; Knowles, R. R., "Isotope Effects and Mechanism(s) of Fragmentation of Alkenyl Iodonium Triflate Salts," Presented at the 56th Southeastern Regional Meeting of the American Chemical Society (SERMACS), Durham, NC, November 10-13, 2004. Abstract 255.
56) Sprachman, M. M.; Litvinas; N. D., Mattern, M. C.; Hinkle, R. J.; Jenkins, A. T.; Burnette, D. C., "Stereoselective Tandem Cyclization-Addition Reactions Using Catalytic BiBr3," Presented at the 56th Southeastern Regional Meeting of the American Chemical Society, Durham, NC, November 10-13, 2004. Poster Presentation 800.
57) Mattern, M. C.; Hinkle, R. J.; "Selective Tandem Reactions Using Catalytic BismuthBromide," 11th Annual William & Mary Undergraduate Research Symposium, Sept. 3, 2004. Poster Presentation.
58) Hassink, M. D.; Hinkle, R. J. "Coupling Using Iodonium Salts," 11th Annual William & Mary Undergraduate Research Symposium, Sept. 3, 2004. Poster Presentation.
59) Sprachman, M. M.; Hinkle, R. J., "The Use of Bismuth Catalysts in Cyclic Ether Synthesis," 11th Annual William & Mary Undergraduate Research Symposium, Sept. 3, 2004. Poster Presentation.
60) Vortherms, A.; Hinkle, R. J., "Iodonium Salt Synthesis and Palladium-Catalyzed Tandem Coupling Reactions," 11th Annual William & Mary Undergraduate Research Symposium, Sept. 3, 2004. Poster Presentation.
61) Gharpure, S. J.; Hinkle, R. J.; Cui, J.; Evans, P. A. "Bismuth Catalyzed Diastereo- selective Etherification Reactions: Application to the Synthesis of Non-Adjacent and Fused Polycyclic Ethers," Presented at the National Organic Symposium, Bloomington, IN June 8-12, 2003. Poster Presentation C94.
62) Litvinas, N. D. Hinkle, R. J. “Trisubstituted Olefin Synthesis by Reaction of Benzylic Zinc Reagents with b,b-Disubstituted Alkenyl(phenyl)iodonium Triflates,” Presented at the 225th American Chemical Society Meeting, New Orleans, LA, March 23-27, 2003. Abstract ORGN-579.
63) Litvinas, N. D. Hinkle, R. J. “Trisubstituted Olefin Synthesis by Reaction of Benzylic Zinc Reagents with -Disubstituted Alkenyl(phenyl)idonium Triflates.” Verizon Undergraduate Research Symposium at William and Mary, September 2002. Poster Presentation.
64) Henry, C. E.; Hinkle, R. J. “ Investigation of Titanium Aryloxy Complexes as Carbocyclization Pre-Catalysts.” Verizon Undergraduate Research Symposium at William and Mary, September 2002. Poster Presentation.
65) Hill, A.; Hinkle, R. J. “Addition of Organozinc Reagents to Alkenyl(phenyl)-iodonium Salts: Syntheses of Trisubstituted Olefines.” Verizon Undergraduate Research Symposium at William and Mary, September. 2002. Poster Presentation.
66) Brochu, M. P.; Hinkle, R. J. "Deuterium Isotope Effects in Iodonium SaltFragmentations," Verizon Undergraduate Research Symposium at William and Mary, September. 2001. Poster Presentation.
67) Mikowski, A. M.; Hinkle, R. J. "Fragmentation Reactions of Alkenyl(aryl)iodoniumSalts," Verizon Undergraduate Research Symposium at William and Mary, September.2001. Poster Presentation.
68) Litvinas, N. D.; Hinkle, R. J. "Organozinc Reactions with Alkenyl(aryl)iodonium Triflates," Verizon Undergraduate Research Symposium at William and Mary, September. 2001. Poster Presentation.
69) Carra, R. J.; Hinkle, R. J., "Cyclization Reactions Utilizing Titanium Aryloxy Compounds," Hinkle, R. J. Verizon Undergraduate Research Symposium at William and Mary, September. 2001. Poster Presentation.
70) Henry, C. E.; Hinkle, R. J., "Titanium Aryloxy Pre-catalysts for Intramolecular Cyclizations," Hinkle, R. J. Verizon Undergraduate Research Symposium at William and Mary, September. 2001. Poster Presentation.
71) Hinkle, R. J.; Rouse, E. A.; McNeil, A. M.; Thomas, Q. A.; Thomas, D. B. "VinylCations from Alkenyl(aryl)iodonium Salts: Are Primary Vinyl Cations involved?" Presented at the 221st American Chemical Society Meeting, San Diego, CA, April 01-05, 2001. Oral Presentation 450.
72) Pasek, M.; Hinkle, R. J., "An Investigation of the Reaction of Alkenyl(aryl)iodoniumSalts with Zinc Reagents," Verizon Undergraduate Science Research Symposium, 15September 2000; Poster Presentation, 54.
73) Mikowski, A. M.; Hinkle, R. J., "The Attempted Synthesis of AlkenylbenziodoxoleDerivatives," Verizon Undergraduate Science Research Symposium, 15 September 2000; Poster Presentation, 52.
74) Rouse, E. A.; Hinkle, R. J., "Primary Vinyl Cations: The Fragmentation of Alkenyl(aryl)iodonium Triflates," Verizon Undergraduate Science Research Symposium, 15 September 2000; Poster Presentation, 62.
75) Hinkle, R. J.; Rouse, E. A.; McNeil, A. J. "Fragmentation of Alkenyl(aryl)iodonium Triflates via Vinyl Cations," Presented at the 220th American Chemical Society Meeting, Washington, DC, August 19-24, 2000. Oral Presentation 295.
76) Hinkle, R. J.; Leri, A. C.; David, G. A.; Erwin, W. M. "Addition of Benzylzinc Halides to Alkenyl(phenyl)iodonium Triflates: Stereoselective Synthesis of Trisub-stituted Alkenes," presented at the 219th National American Chemical Society Meeting, San Francisco, CA, March 26-30, 2000; Poster Presentation, 535.
77) McNeil, A. J.; Hinkle, R. J. "Synthesis and Decomposition of -Disubstituted Alkenyl(aryl)iodonium Triflates." Arnold and Mabel Beckman Scholars Symposium, Irvine, CA, July 1999. Poster Presentation.
78) David, G. A.; Erwin, W. M. Hinkle, R.J. “Addition of Organozinc Reagents to Alkenyl(phenyl)iodonium Triflates: Synthesis of Trisubstituted Alkenes.” Southeast Regional Meeting of the American Chemical Society (SERMACS), Knoxville, TN, 17-20October 1999, abstract 381. Poster Presentation.
79) Leri, A. C.; Hinkle, R. J. “Cross-couplings Between Alkenyl(aryl)iodonium Salts and Organozinc Reagents.” Undergraduate Meeting in Miniature of the Southeast Regional Meeting of the American Chemical Society (SERMACS), Knoxville, TN, 16-17 October 1999, abstract 40. Poster presenter awarded $75.00 cash for excellence in the session.
80) David, G. A.; Hinkle, R. J. “Reactions of Vinyl Iodonium Triflate Salts and Organozinc Reagents.” GTE Undergraduate Science Research Symposium, 10 September 1999. Poster Presentation.
81) Leri, A. C.; Hinkle, R. J. “Cross-couplings Between Alkenyl(aryl)iodonium Triflate Salts and Organozinc Reagents.” GTE Undergraduate Science Research Symposium, 10 September 1999. Poster Presentation.
82) Andrews, M. N.; Hinkle, R. J. “Attempted Syntheses of Vinyl Benziodoxoles.” GTE Undergraduate Science Research Symposium, 10 September 1999. Poster Presentation.
83) McNeil, A. J.; Thomas, Q. B.; Andrews, M. N. (Robert J. Hinkle), 13th National
Conference on Undergraduate Research, April 8-10, University of Rochester, Rochester, NY. Poster Presentation.
PATENTS
1) Coinventor of Hickman-Hinkle and similar distillation columns sold by Ace® and
Corning® Glass companies; U. S. Patent 4,770,746 (1987).
PROFESSIONAL SERVICE (past and present)
1) Chair, Working Group on the Use of Teaching Assistants in the Undergraduate Classroom, 2024-2025.
2) Chair, search for Senior Associate Dean for Finance and Administration for Arts & Sciences, Fall 2023
3) Member of Threat Assessment Team at W&M, 2021-2023.
4) Co-Chair of the W&M Council of Chairs and Program Directors, Jan. 2020 to Dec. 2020
5) Annual Presenter at W&M School of Education Day for Underrepresented Students; July 2018 to present.
6) Annual Presenter at W&M School of Education Day for Gifted students; January from 2017 to present.
7) Poster Award Selection Committee, 46th National Organic Symposium (June 2019).
8) Presided over a session at the 254th National Meeting of the American Chemical Society, Washington, DC, August 21, 2017.
9) Tenure Review for professor at PUI; details confidential.
10) Departmental Review Team for PUI university (March 2018).
11) Chair, Department of Chemistry (July 2017 to June 2021).
12) Member, Committee to Evaluate W&M Vice President for Advancement, Matthew Lambert (fall 2015-spring 2016).
13) Chair, Nominations & Elections Committee for Arts and Sciences (summer 2014—
spring 2015).
14) Beckman Scholar’s Selection Committee (spring 2015, 2017, 2018).
15) HHMI Student Selection Committee (spring 2014 & 2016).
16) Nominations and Elections Committee (fall 2012—spring 2015).
17) Chemistry NTE Faculty Search Committee (fall 2013).
18) Chair, Athletic Policy Committee (fall 2013–fall 2016).
19) Committee to Evaluate W&M Vice President of Finances, Sam Jones (spring 2013).
20) National Advisory Committee for national funding agency, 2012.
21) Chemistry Faculty Search Committee, Chair (fall 2011).
22) Athletic Policy Committee (2011-2012).
23) American Chemical Society (ACS) National Award Committee—years, dates, committee confidential.
24) Learning Space Study Committee (2010).
25) Swem Library Policy Committee (2010--2012).
26) Gordon Research Conference Discussion Leader for David W. C. MacMillan and Shu
Kobayashi, July 2009.
27) HHMI fellowship selection committee, 2008, 2009, 2011
28) Chair of Building and Safety Committee, Chemistry (Fall 2006 to 2009).
29) Graduate Program Committee, Chemistry--continuing.
30) Instrumentation Committee, Chemistry 2008, 2009.
31) Arkivok Board of Referees (online peer-reviewed journal, 2002 to 2009).
32) Presided over National American Chemical Society (ACS) Meeting Symposium
Session, August 31, 2005.
33) Chair of Instrumentation Committee, chemistry (fall 2005 to spring 2006).
34) NSF Review Panel Participant (2004).
35) Chair of Chemistry Seminar Committee (spring 2004-fall 2006).
36) Rogers Expansion and Renovation Committee.
37) Goldwater Scholarship Committee member and Chemistry Liason (beginning 08/01).
38) Faculty Search Committee (Fall, '01), Department of Chemistry.
39) College Committee on Academic Space Planning (Aug. 2002 to 2005).
40) Appeared before Board of Visitors for chemistry building renovation hearing.
41) Provided information and conducted a departmental tour for a State Council of
Higher Education of Virginia (SCHEV) Capital Spending Representative.
34) Provided information and conducted a departmental tour for the Board of Visitors
Buildings and Grounds Committee.
35) Rogers Hall Renovation and Expansion Pre-Planning Committee.
36) Howard Hughes Medical Institute Planning Committee.
37) Co-Chair (with Patty Zwollo of Biology) of Howard Hughes Medical Institute
38) Seminar Committee.
39) Beckman Scholars Grant Participant.
40) Chair of Chemistry Library Committee.
41) Alpha Lamda Phi Honor Society Advisor.
42) Curriculum Committee, Department of Chemistry
43) Computer Proficiency Assessment Committee, Department of Chemistry.
44) Presented annual student GRE review session ('99-'00).
45) Monroe Scholar Luncheon Speaker.
46) Departmental Secretary 1/97-8/97.
47) Volunteer for Student Open House (April 19, 1997).
48) Graduate Committees
M.S. Committees
Lauren C. Green (Chair), 2023
Caleb Burns (Chair), 2021
Nicholas Angelo, 2018
Shane E. Lewis (Chair), 2014
Yuzhou Chen (Chair), 2014
Stephen Laws, 2013
Todd Hovey, 2011
Sara Kampfe (Chair), 2010
Jia Liu (Chair), 2009
Matthew Jones, 2008
Yajing Lian (Chair), 2006
Elizabeth Miller, 2000
Ph. D. Committees:
Zhenrong Guo, July 2005
COMMUNITY
Board of Directors, Colonial Road Runners, 2003-2005
HOBBIES
Mountain Biking, Hiking, Furniture making, Metalworking, Motorcycling.
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