The Zhang research Group
We play with photons
We develop novel optical spectroscopy, imaging, and opto-control technologies and apply them to study chemistry in living samples. We use chemical imaging to answer questions in biological and medical sciences and develop new opto-control platforms to precisely control chemical processes in live cells.
Group News
12/18/2024
Congratulations to Shivam and Karsten for receiving the College of Science Graduate Student Travel Award for 2025.
12/10/2024
Congratulations to Seohee Ma for receiving the Women in Science Program (WISP) travel grant for the upcoming SPIE Photonics West.
11/10/2024
Mingmin Zhou and Callum Appel joined our group for Ph.D. study! Welcome!
10/24/2024
Congratulations to Karsten Mohn for passing his OP!
10/01/2024
Chemical and Biomedical Imaging (ACS journal) has accepted Gil's first-authored paper on hypoxia-induced cancer lipid metabolism change for publication. Congratulations to Gil and coauthors!
08/23/2024
Welcome, Ambhranee and Ishaan, to our group! We're excited to have you join us. And welcome back, Natalie—we're glad to have you continue working with us this semester.
08/20/2024
Jesse presented an invited talk at the ACS Fall 2024 in Denver.
08/19/2024
Congratulations to Laura Lukov for receiving the Presidential Doctoral Excellence Award!
08/13/2024
Congratulations to Shivam and co-authors for publishing their work in VIEW!
08/02/2024
Jesse presented an invited talk at ICORS at Sapienza University of Rome.
07/03/2024
Congratulations to Gil on receiving his Ph.D. degree! The second Ph.D. student from our lab!
06/05/2024
Matt's low-wavenumber SRS microscopy paper has been accepted for publication in Analytical Chemistry. Our graphic design was selected as the supplementary cover of Analytical Chemistry.
06/05/2024
We received the 2024-2025 Showalter Trusk Research Award with a total fund of $75,000 for using RPOC technology to manipulate cell division!
05/31/2024
We received a $30,000 Award from the Purdue Trask Foundation to commercialize the RPOC technology.
05/23/2024
Bin presented an oral talk 9th Annual Hitchhiker's Guide to the Biomolecular Galaxy 2024, Shivam also gave a poster presentation.
05/09/2024
Karsten presented at the CBM symposium at IU Bloomington
05/01/2024
Karsten and Shivam presented posters in the OIGP poster session.
04/22/2024
Jesus received his M.S. degree in Chemistry. Congratulations!
04/18/2024
Jesse presented at the Purdue Innovation Expo.
03/08/2024
Congratulations to Matthew Clark for his successful Ph.D. defense. Matt is the first Ph.D. student in our group!
01/31/2024
Jesse, Matt, and Bin presented at SPIE Photonics West. Congratulations to Bin on receiving the best paper in the conference 12840, Optical Interactions with Tissue and Cells XXXV.
01/26/2024
Our paper "Spatiotemporally Precise Optical Manipulation of Intracellular Molecular Activities" is published in Advanced Science.
01/03/2024
Dr. Chi Zhang will teach CHM424 in the spring semester of 2024.
Selected publications
B. Dong#, S. Mahapatra#, M.G. Clark, et al. and C. Zhang*. "Spatiotemporal precise optical manipulation of intracellular molecular activities", Advanced Science, 2307342 (2024) Link
M.G. Clark, G. Gonzalez, Y. Luo, J. Aldana-Mendoza, M.S. Carlsen, G. Eakins, M. Dai, and C. Zhang*. "Real-time precision opto-control of chemical processes in live cells". Nature Communications, 13, 4343 (2022). Link
M.G. Clark, K.J. Mohn, B. Dong, H.C. Campbell, and C. Zhang*. "Frequency-domain low-wavenumber hyperspectral stimulated Raman scattering microscopy", Analytical Chemistry, (2024) 96 (25) 10341–10347. Link
M.G. Clark, G. Gonzalez, and C. Zhang*. "Pulse-picking multimodal nonlinear optical microscopy". Analytical Chemistry 94, 15405–15414 (2022). Link
S. Mahapatra, S. Ma, B. Dong, and C. Zhang*. "Quantification of cellular phototoxicity of organelle stains by the dynamics of microtubule polymerization" VIEW, 20240013 (2024). Link
G. Gonzalez, E. Osuji, N. Fiur, M. Clark, S. Ma, L. Lukov, and C. Zhang*. "Alternation of lipid metabolism in hypoxia cancer cells". Chemical & Biomedical Imaging, (2024) In Press. Link