Harris, N., D. Born, W. Cai, Y. Huang, J. Martin, R. Khalaf, C. Drennan, and W. Zhang. "Isonitrile Formation by a Non-heme Iron(II)-Dependent Oxidase/Decarboxylase." Angew. Chem. 2018, 57, 9707-9710. (VIP) Link 

Su, M., X. Zhu, and W. Zhang. "Probing the Acyl Carrier Protein-Enzyme Interactions Within Terminal Alkyne Biosynthetic Machinery." AIChE J. 2018, 64, 4255-4262. (TRIBUTE TO FOUNDERS: JAY BAILEY) Link

Skyrud, W., Liu, J., Thankachan, D., Cabrera, M., Seipke, R., and W. Zhang. "Biosynthesis of the 15-Membered Ring Depsipeptide Neoantimycin." ACS Chem. Biol. 2018, 13, 5, 1398-1406. Link

Liu, J., Kaganjo, J., Zhang, W., Zeilstra-Ryalls, J. "Investigating the bifunctionality of cyclizing and "classical" 5-aminolevulinate synthases." Protein Sci. 2018, 27, 2, 402-410. Link

Twigg, F., Skyrud, D., Li, J., Zhang, W. "Chapter 10: Engineering Enzymes for Natural Products Biosynthesis and Diversification." In G. Williams & Melanie Hall (Eds), Modern Biocatalysis: Advances Towards Synthetic Biological Systems. 2018, 261-286. Link

Zhu, X. and Zhang, W. "Terminal Alkyne Biosynthesis in Marine Microbes." Methods Enzymol. 2018, 604, 89-112. Link

Cai, W. and Zhang, W. "Engineering modular polyketide synthases for production of biofuels and industrial chemicals." Curr. Opin. Biotechnol. 2018, 50, 32-38 Link

Herman, N. A., Kim, S., Li, J. S., Cai, W., Koshino, H., Zhang, W. "The industrial anaerobe Clostridium acetobutylicum uses polyketides to regulate cellular differentiation." Nat. Commun. 2017, 8, 1514 Link

Harris, N. C., Sato, M., Herman, N. A., Twigg, F., Cai, W., Liu, J., Downey, J., Khalaf, R., Martin, J., Koshino, H., Zhang, W. "Biosynthesis of isonitrile lipopeptides by conserved non-ribosomal peptide synthetase gene clusters in Actinobacteria." Proc. Natl. Acad. Sci. U. S. A. 2017, 114, 27, 7025-7030. Link

Herman, N., Li, J., Bedi, R., Turchi, B., Liu, X., Miller, M., Zhang, W. "Development of a high-efficiency transformation method and implementation of rational metabolic engineering for the industrial butanol hyper-producer Clostridium saccharoperbutylacetonicum strain N1-4." Appl. Environ. Microbiol. 2017, 83, 2, e02942-16. Link

Herman, N., Zhang, W. "Enzymes for fatty-acid based hydrocarbon biosynthesis." Curr. Opin. Chem. Biol. 2016, 35, 22-28. Link

Zhu, X., Shieh, P., Su, M., Bertozzi, C., Zhang, W. "A fluorogenic screening platform enables directed evolution of an alkyne biosynthetic tool." Chem. Commun. 2016, 52, 11239-11242. Link

Liu, J., Zhu, X., Kim, S., Zhang, W. "Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities." Nat. Prod. Rep. 2016, 33, 1146-1165. Link

Rui, Z., Zhang, W. "Combining genome mining and biosynthesis research to discover bioactive natural products and new targets for medicinal chemistry" Curr. Top. Med. Chem. 2016, 16, 1643-1644. (Editorial) Link

Rui, Z., Zhang, W."Engineering biosynthesis of non-ribosomal peptides and polyketides by directed evolution" Curr. Top. Med. Chem. 2016, 16, 1755-1762. Link

Liu, J., Zhang, W. "Recent advances in understanding and engineering polyketide synthesis." F1000 Faculty Rev. 2016, 5. Link

Rui, Z., Harris, N. C., Zhu, X., Huang, W., Zhang, W. "Discovery of a family of desaturase-like enzymes for 1-alkene biosynthesis." ACS Catal. 2015, 5, 7091-7094. Link

Huang, W., Kim, S., Liu, J., Zhang, W. "Identification of the polyketide biosynthetic machinery for the indolizidine alkaloid cyclizidine." Org. Lett. 2015, 17, 5344-5347. Link

Liu, J., Zhu, X., Zhang, W. "Identifying the minimal enzymes required for biosynthesis of epoxyketone proteasome inhibitors." ChemBioChem. 2015, 16, 2585-2589. Link

Zhu, X., Su, M., Manickam, K., Zhang, W. "Bacterial genome mining of enzymatic tools for alkyne biosynthesis." ACS Chem. Biol. 2015, 10, 2785-2793. Link

Rui, Z., Huang, W., Xu, F., Han, M., Liu, X., Lin, S., Zhang, W. "Sparsomycin biosynthesis highlights unusual module architecture and processing mechanism in non-ribosomal peptide synthetase." ACS Chem. Biol. 2015, 10, 1765-1769. Link

Zhu, X., Zhang, W. "Tagging polyketides/non-ribosomal peptides with a clickable functionality and applications." Front. Chem. 2015, 3: 11. Link

Zhu, X., Liu, J., Zhang, W. "De novo biosynthesis of terminal alkyne-labeled natural products." Nat. Chem. Biol. 2015, 11, 115-120. Link.

Rui, Z., Li, X., Zhu, X., Liu, J., Domigan, B., Barr, I., Cate, J. H. D., Zhang, W. "Microbial biosynthesis of medium-chain 1-alkenes by a non-heme iron oxidase." Proc. Natl. Acad. Sci. U. S. A. 2014, 111, 18237-18242. Link Highlight in Angew. Chem.

Liu, J., Zhu, X., Seipke, R. F., Zhang, W. “Biosynthesis of antimycins with a reconstituted 3-formamidosalicylate pharmacophore in Escherichia coli.” ACS Synth. Biol. 2015, 4, 559-565. Link

Liu, J., Ng, T., Rui, Z., Ad, O., Zhang, W. “Unusual acetylation-dependent reaction cascade in the biosynthesis of the pyrroloindole drug physostigmine.” Angew. Chem. Int. Ed. Engl. 2014, 53, 136-139. Link 

Sandy, M., Zhu, X., Rui, Z., Zhang, W. “Characterization of AntB, a promiscuous acyltransferase involved in antimycin biosynthesis.” Org. Lett. 2013, 15, 3396-3399. Link

Rui, Z., Sandy, M., Jung, B., Zhang, W. "Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites." Chem. Biol. 2013, 20, 859-860. Link

Sandy, M., Rui, Z., Gallagher, J., Zhang, W. “Enzymatic synthesis of dilactone scaffold of antimycins.” ACS Chem. Biol. 2012, 7, 1956-1961. Link

Rui, Z., Ye, M., Wang, S., Fujikawa, K., Akerele, B., Aung, M., Floss, H., Zhang, W., Yu, T. “Insights into a divergent phenazine biosynthetic pathway governed by a plasmid-born esmeraldin gene cluster.” Chem. Biol. 2012, 19, 1116-1125. Link

Walsh, C. T., Zhang, W. “Chemical logic and enzymatic machinery for biological assembly of peptidyl nucleoside antibiotics.” ACS Chem. Bio. 2011, 6, 1000-1007. Link

Ames, B. D., Lee, M. Y., Moody, C. L., Zhang, W., Tang, Y., Tsai, S. C. “Structural and biochemical characterization of ZhuI aromatase/cyclase from the R1128 polyketide pathway.” Biochemistry 2011, 50, 8392-8406. Link

Qiao, K., Zhou, H., Xu, W., Zhang, W., Garg, N., Tang, Y. “A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines” Org. Lett. 2011, 13, 1758-1761. Link