주요 연구 논문

[2026] Not All GLP-1 Receptor Agonists Are Alike: Real-World Evidence of Differential Endocrine and Dermatologic Safety.

Diabetes/Metabolism Research and Reviews

[2026] Association of GLP-1 Receptor Agonists With Hepatic Decompensation in the All of Us Research Program.

Inyoung Hwang , Yun Kim , Sang Won Lee 

Diabetes Obesity and Metabolism

[2026] Model-Informed Prediction of Human Pharmacokinetics and First-in-Human Dose Selection of J2H-1702, a Novel 11ß-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Metabolic-Associated Steatohepatitis.

Inkyu Kim , Inyoung Hwang , Sang Won Lee , Yun Kim

European Journal of Pharmaceutical Sciences

[2026] Intrahepatic Cholestasis of Pregnancy Associated with Azathioprine: First Quantitative Disproportionality Analysis Using the FDA Adverse Event Reporting System.

Yonghoon Kwon, Nai Lee, Yun Kim

Journal of Pharmacy & Pharmaceutical Sciences

[2025] Toward Genotype-Informed Dosing of Voriconazole: Head-to-Head Simulations Across CYP2C19 Phenotypes Using Population Pharmacokinetic Models.

Yeobin Lee, Nai Lee, Su-jin Rhee and Yun Kim

Pharmaceutics

[2025] Safety, Pharmacokinetics, and Food Effect of the RORα Agonist TB-840, a Novel Candidate for Metabolic dysfunction-associated steatohepatitis (MASH): A Randomized First-in-Human Study in Healthy Volunteers.

Inyoung Hwang , Shi-Ra Lee, Heung Jae Kim, Yun Kim , Sang Won Lee 

Life

[2025] Immune Landscape Changes in MASLD and the Effects of 11β-HSD1 Inhibition Revealed by Single-Cell Mass Cytometry.

IZayakhuu Gerelkhuu , Sehee Park , Yun Kim, Sang Won Lee, Dae Won Jun, Tae Hyun Yoon

Proteomics Clinical Applications

[2025] Evaluating the Association between Migraine Treatments and Tinnitus: Insights from the US Food and Drug Administration Adverse Event Reporting System.

Yun Kim , Yeabin Yook, Su-jin Rhee 

PLOS ONE

[2025] Comparison of Sarcopenia Screening Indices Using Serum Creatinine and Cystatin C in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Inyoung Hwang , Shi-Ra Lee, Yun Kim , Sang Won Lee 

Frontiers in Medicine

[2025] Identifying Signals of Disproportionate Reporting for Calcitonin Gene-Related Peptide Inhibitors: Real-World Evidence from the FDA Adverse Event Reporting System.

Nai Lee , Jihoon Ok, Yonghoon Kwon, Su-jin Rhee, Yun Kim 

Expert Opinion On Drug Safety

[2025] Impact of Sirolimus on Long‐Term Adverse Cardiovascular Outcomes in Kidney Transplant Recipients: A Nationwide Cohort Study

Jinhyun Park , Wonhui Choi, Jinseub Hwang, Ha young Jang, Yun Kim , Young-Mi Ah, Jin-Won Kwon, Kyung Hee Choi, Yun-Kyoung Song

European Journal of Clinical Investigation

[2025] A Novel 11β-HSD1 Inhibitor Ameliorates Liver Fibrosis by Inhibiting the Notch Signaling Pathway and Increasing NK Cell Population.

Ji Eun Kim , Yun Kim ,Jiwon Bae, Eileen Laurel Yoon, Hyun Sung Kim, Sung Ryol Lee, Tae Hyun Woon, Dae Won Jun

Archives of Pharmacal Research

[2025] Disproportionality Analysis of Raynaud’s Phenomenon Associated with Calcitonin Gene-Related Peptide Inhibitors Using the Food and Drug Administration Adverse Event Reporting System.

Nai Lee , Ji hoon Ok, Su-jin Rhee, Yun Kim 

Scientific Reports

[2025] Navigating Recent Changes in Dosing Information: Dynamics of FDA-Approved Monoclonal Antibodies in Post-Marketing Realities.

Nai Lee , Su-jin Rhee, Seong Min Koo, So Won Kim, Gyo Eun Lee, Yoon a Yie, Yun Kim 

Clinical and Translational Science

[2024] Multi-Modal Fusion-based Lightweight Model for Enhanced Generalization in Drug-Target Interaction Prediction.

Jonghyun Lee, Dokyoon Kim, Dae Won Jun, Yun Kim 

Journal of Chemical Information and Modeling

[2024] Assessing Post-Marketing Requirements for Orphan Drugs: A Cross-Sectional Analysis of FDA and EMA Oversight.

Jae Hyeon Yu, Sangwon Lee, Yoon Jung Kim, Won Young Kim, Min Jung Lee, Yun Kim 

Clinical Pharmacology & Therapeutics

[2024] Optimal Once-Daily Busulfan Administration in Pediatric Patients: A Simulation-Based Investigation of Intravenous Infusion Times.

Yun Kim , Sungha Moon, Su-Jin Rhee 

Drug Design, Development and Therapy

[2024] DLM-DTI: a dual language model for the prediction of drug-target interaction with hint-based learning.

Jonghyun Lee, Dae Won Jun , Idae Song, Yun Kim 

Journal of Cheminformatics

[2023] Editorial: Liver hypercortisolism as a potential target for MASH treatment—Authors' reply.

Yun Kim , Inyoung Hwang Sang Won Lee 

Alimentary Pharmacology & Therapeutics

[2023] First in Human Randomized Trial of J2H-1702: a Novel 11β-hydroxysteroid Dehydrogenase Type 1 Inhibitor for Nonalcoholic Steatohepatitis Treatment.

Yun Kim , Shi-Ra Lee, Sang Won Lee 

Alimentary Pharmacology & Therapeutics

[2023] The drug-like molecule pre-training strategy for drug discovery.

Jonghyun Lee, In-Soo Myeong, Yun Kim  

IEEE Access

[2023] Synthesis of Protected 1,4-trans-1,5-cis-4,5-Diamino-2-cyclopenten-1-ol via Stereoselective Vinylation of a-Amino Aldimine.

Seung Jong Lee , Yun Kim , Won-Hun Ham, In-Soo Myeong

Tetrahedron Letters

[2022] ALS-L1023 from Melissa officinalis Alleviates Liver Fibrosis in a Non-Alcoholic Fatty Liver Disease Model.

Eun Jeoung Lee, Yun Kim , Ji Eun Kim, Eileen Laurel Yoon, Sung Ryol Lee, Dae Won Jun 

Life

[2022] Pharmacokinetic and pharmacodynamic interaction of DWP16001, a sodium-glucose cotransporter 2 inhibitor, with gemigliptin and metformin in healthy adults

Sae Im Jeong , Yun Kim , Jae Jin Nah, Wan Huh, In-Jin Jang, Jun Gi Hwang, SeungHwan Lee

Br J Clin Pharmacology

[2022] Pharmacokinetic and pharmacodynamic interaction between DWP16001, an sodium-glucose cotransporter 2 inhibitor and metformin in healthy subjects.

Byungwook Kim, Ki Young Huh, Jun Gi Hwang, JaeJin Nah, Wan Huh, Jae Min Cho, In-Jin Jang, Kyung-Sang Yu, Yun Kim , SeungHwan Lee 

Br J Clin Pharmacology

[2022] Regulation of Hepatocyte Nuclear Factor 4α Attenuated Lipotoxicity but Increased Bile Acid Toxicity in Non-Alcoholic Fatty Liver Disease.

Yoon Jin Roh, Yun Kim, Jae Sun Lee, Ju Hee Oh, Eileen Laurel Yoon, Sung Ryol Lee, Dae Won Jun 

Life

[2022] Mass cytometry study on hepatic fibrosis and its drug induced recovery using mouse peripheral blood mononuclear cells.

Jiwon Bae, Ji Eun Kim, Haribalan Perumalsamy, SeHee Park, Yun Kim, Dae Won Jun, Tae Hyun Yoon 

Frontiers in Immunology

[2022] Clinical Response and Hospital Costs of Therapeutic Drug Monitoring for Vancomycin in Elderly Patients.

Yun Kim, Soohyun Kim, Jinsook Park, Howard Lee

Journal of Personalized Medicine

[2021] Pharmacokinetics and safety of a novel influenza treatment (baloxavir marboxil) in Korean subjects compared with Japanese subjects

Yun Kim, Sangwon Lee, Wohan Kim, In-Jin Jang , SeungHwan Lee

Clincal Translational Science

[2021] Pharmacokinetics of Ginsenoside Compound K From a Compound K Fermentation Product, CK-30, and From Red Ginseng Extract in Healthy Korean Subjects.

Mu seong Ban, Yun Kim, Sunyoung Lee, ByongYeul Han, Kyung-Sang Yu, In-Jin Jang, Hong Keun Chung, SeungHwan Lee

Clinical Pharmacology in Drug Development

[2021] Emerging Treatment Options for Sarcopenia in Chronic Liver Disease.

Yun Kim

Life

[2021] Population pharmacokinetic/pharmacodynamic modeling of delayed effect of escitalopram-induced QT prolongation.

Yun Kim, Anhye Kim, Jae-Yong Chung 

Journal of  Affective Disorders

[2020] Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects.

Inyoung Hwang, Yun Kim, Hyounggyoon Yoo, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug Design, Development and Therapy

[2020] Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects.

Hyounggyoon Yoo, Yun Kim, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee

Drug Design, Development and Therapy

[2020] Phase I and pharmacokinetic study of the vascular-disrupting agent CKD-516 (NOV120401) in patients with refractory solid tumors.

Hark Kyun Kim, Jeong Won Kang, Young-Whan Park, Jung Young Kim, Minchae Kim, Soo Jin Kim, Se-Mi Kim, Keun Ho Ryu, Seonghae Yoon, Yun Kim, Joo-Youn Cho, Keun Seok Lee, Tak Yun, Kiwon Kim, Mi Hyang Kwak, Tae-Sung Kim, Jinsoo Chung, Joong-Won Park

Pharmacology Research & Perspectives

[2019] Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects

Yun Kim, Seonghae Yoon, Yewon Choi, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, Jae Yong Chung

Scientific Reports

[2019] Development of a Korean-specific virtual population for physiologically based pharmacokinetic modelling and simulation.

Byungwook Kim, Ki Young Huh, Jun Gi Hwang, JaeJin Nah, Wan Huh, Jae Min Cho, In-Jin Jang, Kyung-Sang Yu, Yun Kim , SeungHwan Lee 

Biopharmaceutics & Drug Disposition

[2019] A Personalized CYP2C19 Phenotype -Guided Dosing Regimen of Voriconazole Using a Population Pharmacokinetic Analysis.

Byungwook Kim, Ki Young Huh, Jun Gi Hwang, JaeJin Nah, Wan Huh, Jae Min Cho, In-Jin Jang, Kyung-Sang Yu, Yun Kim , SeungHwan Lee 

Journal of Clinical Medicine

[2019] Development of a physiologically-based pharmacokinetic model for cyclosporine in Asian children with renal impairment.

Sumin Yoon, Sojeong Yi, Su-Jin Rhee, Hyun A Lee, Yun Kim, Kyung-Sang Yu, Jae-Yong Chung

Transliational And Clinical Pharmacology

[2018] A pharmacokinetic drug-drug interaction study between pregabalin and tramadol in healthy volunteers.

Soyoung Lee, Yun Kim, Janice Ji Sung  Lee, Guangjin Im, Joo-Youn Cho, Jae-Yong Chung, Seonghae Yoon

European Journal of Clinical Pharmacology

[2017] Pharmacokinetics, Safety, and Tolerability of Tedizolid Phosphate After Single-dose Administration in Healthy Korean Male Subjects.

Yun Kim, Anhye Kim, SeungHwan Lee, Sung-Hak Choi, Dae young Lee, Ji-Su Song, Howard Lee, In-Jin Jang, Kyung-Sang Yu

Clinical Therapeutics

[2017] Pharmacokinetic comparison of two formulations of talniflumate 370 mg tablets in healthy Korean volunteers.

Yun Kim, Sung-Yim, Bo-Hyung Kim, SeungHwan Lee

International Journal of Clinical Pharmacology