Yuika UEDA / 上田 唯花

Interests
Mechanisms of Cellular Homeostasis and Adaptability

生細胞の力学的適応・ホメオスタシスのメカニズム

Field

Mechanobiology / Biomechanics / Biophysics / Theoretical Biology

Theme

Thermodynamics, Statistical mechanics, and Information thermodynamics approach to cellular homeostasis and adaptability

Education

• 2025 - Present : Visiting PhD student
  University College London, London Centre for Nanotechnology

• 2023 - Present : PhD of Engineering (Bioengineering)
  Osaka University, Graduate School of Engineering Science, Department of Mechanical Science and Bioengineering 

• 2022 : Master of Engineering (Bioengineering)                           

Osaka University, Graduate School of Engineering Science, Department of Mechanical Science and Bioengineering

• 2020 : Bachelor of Engineering (Bioengineering)
  Osaka University, School of Engineering Science

Career

• 2024 - Present : JSPS Young Scientists DC1

• 2022 - 2024 : MITSUI & CO., LTD. 

Selected Publications

• 〇Yuika Ueda and Shinji Deguchi. "Adaptive flexibility of cytoskeletal structures through nonequilibrium entropy production"  BioSystems (2025): 105594. [link]

• 〇Yuika Ueda and Shinji Deguchi. "Intracellular order formation through stepwise phase transitions." arXiv preprint arXiv:2408.14242 (2024). (Preprint)  [link]

• 〇Yuika Ueda and Shinji Deguchi. "Nonthermal driving forces in cells revealed by nonequilibrium fluctuations." arXiv preprint arXiv:2408.06683 (2024). (Preprint)  [link]

• 〇Yuika Ueda, Daiki Matsunaga, and Shinji Deguchi. "Asymmetric response emerges between creation and disintegration of force-bearing subcellular structures as revealed by percolation analysis." Integrative Biology 16, zyae012, 2024 [link]

• 〇Yuika Ueda and Shinji Deguchi. "Emergence of multiple set-points of cellular homeostatic tension" Journal of Biomechanics 151 (2023): 111543[link]

• 〇Yuika Ueda, Daiki Matsunaga, and Shinji Deguchi. "A statistical mechanics model for determining the length distribution of actin filaments under cellular tensional homeostasis" Scientific Reports 12 (2022): 14466.  [link]

Grant & Fellowship

1. 2025 - 2027 : Japan Science and Technology Agency  (JST) ACT-X Life and Information
   "Information Flows Underlying Cellular Adaptability Hidden in Functional Fluctuations"

2. 2024 - 2027 : Japan Society for the Promotion of Science (JSPS) Research Fellowship DC1
   "張力ホメオスタシスに係る細胞現象の材料熱統計力学"

3. 2024 - 2026 : Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering 

4. 2025：2025年度リカケンホールディングス若手研究者助成
   "非平衡ゆらぎから紐解く細胞力学的適応性のメカニズム解明"

5. 2025：大阪大学次世代グローバルリーダー海外派遣プログラム
   "Mechanical Adaptive Mechanisms in Cell Division and Their Impact on Tissue Formation"

6. 2025：The Great Britatin SASAKAWA FOUNDATION
   "Development of methods for quantitative analysis of actin cortex in cells to elucidate the cancer process"

7. 2024 - 2025 : The ANRI Fellowship
   “細胞力学的適応に関する非平衡物理学”

8. 2025 : scholarship partners. Drive Your Impact

9. 2024 : 日本生体医工学会齋藤奨学金
   "非平衡ゆらぎに基づく細胞力学特性の計測法の開発"

10. 2024 : マルチモダルECM若手研究者国際活動支援
    "情報熱力学に基づくがん細胞血管外遊走メカニズムの解明 : Revealing the mechanism of cancer cell extravasation based on information thermodynamics"

11. 2024 : 大阪大学基礎工学研究科2024年度海外派遣プログラム短期留学支援
    "Thermodynamics and Statistical Mechanics of Cellular Tensional Homeostasis "