THE YOUNT LABORATORY OF INNATE ANTIVIRAL IMMUNOLOGY


Associate Professor

Department of Microbial Infection and Immunity

Co-Director

Viruses and Emerging Pathogens Program of the OSU Infectious Disesases Institute

The Ohio State University

Address: 460 W 12th Ave Biomedical Research Tower 790 Columbus, OH 43210

Email: Yount.37@osu.edu Phone: 614-688-1639

Department Faculty Website

@YountLabOSU Twitter

Google Scholar



The Yount laboratory aims to understand the innate immune response to respiratory and cardiac virus infections, with a focus on influenza virus, human metapneumovirus, Coxsackievirus, and SARS-CoV-2 infections. We are particularly interested in identifying and characterizing posttranslational modifications that govern the activity of immune system proteins. These enzymatic modifications may represent targets for mimicking or manipulating immune pathways for the benefit of human health. We have made significant progress in understanding the regulation and mechanism of action of the interferon-induced transmembrane protein 3 (IFITM3), a critical protein for limiting the severity of influenza virus infections in humans. We continue to investigate new aspects of IFITM3 biology as well as other essential immune effector proteins and their posttranslational regulation.


Yount Lab Research News

No evidence that COVID-19 vaccine results in sterilization -- Dr. Yount quoted by AP News

Study finds specific proteins that inhibit or enhance virus that causes COVID-19

New lab test clarifies the potential protective effects of COVID-19 antibodies

Stopping lethal lung damage from flu with a natural human protein

FDA approves COVID_19 innovations; Ohio State Medical Center to share nationwide

Genetic Mutation Linked to Flu Related Heart Complications

Molecular scissors could be key to cutting off diseases including HIV infection

One drug to prevent all forms of flu -- Dr. Yount podcast interview

Could flu someday be prevented without a vaccine?