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KONDO Yohei, Ph.D.
Research field: Chemical biology
Research keyword: Molecular imaging, Molecular probe, Photochemistry, Nulcear magnetic resonance (NMR), Dynamic nulear polarization (DNP)
[Education]
2009–2012: Tokyo Metropolitan Nishi High School
2013–2015: Natural ScienceⅠ, College of Arts and Sciences, The University of Tokyo
2015–2017: Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo
2017–2022: Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo (Prof. Shinsuke Sando)
2018–2022: World-leading Innovative Graduate Study program for Materials Research, Information, and Technology（MERIT-WINGS)
[Work]
2019–2022: JSPS Research Fellowship for Young Scientists（DC1）
2022–2023: Researcher, Mitsubishi Research Institute
2023–2024: Assistant Professor, School of Life Science and Technology, Department of Life Science and Technology, Tokyo Institute of Technology (Prof. Kiyohiko Kawai)
2024–Current: Assistant Professor, School of Life Science and Technology, Department of Life Science and Technology, Institute of Science Tokyo (Prof. Kiyohiko Kawai)
[5] "Sensing the concentration of biological reductants through single-molecule fluorescence blinking"
Yohei Kondo, Shotaro Tsuchitori, Yuki Yonezawa, Tadao Takada, Atsushi Maruyama, Mamoru Fujitsuka, Kiyohiko Kawai
J. Phys. Chem. Lett. 2025, 16, 5202–5207. DOI: 10.1021/acs.jpclett.5c00475
[4] "Directly monitoring the dynamic in vivo metabolisms of hyperpolarized 13C-oligopeptides"
Yohei Kondo, Yutaro Saito, Tomohiro Seki, Yoichi Takakusagi, Norikazu Koyasu, Keita Saito, Jumpei Morimoto, Hiroshi Nonaka, Koichiro Miyanishi, Wataru Mizukami, Makoto Negoro, Abdelazim Elsayed Elhelaly, Fuminori Hyodo, Masayuki Matsuo, Natarajan Raju, Rolf Swenson, Murali C. Krishna, Kazutoshi Yamamoto, Shinsuke Sando
Sci. Adv. 2024, 10, eadp2533. DOI: 10.1126/sciadv.adp2533
Preprint: ChemRxiv 2022, DOI: 10.26434/chemrxiv-2022-tfkk1
[3] "Structure-guided design enables development of a hyperpolarized molecular probe for the detection of aminopeptidase N activity in vivo"
Yutaro Saito, Hiroyuki Yatabe, Iori Tamura, Yohei Kondo, Ryo Ishida, Tomohiro Seki, Keita Hiraga, Akihiro Eguchi, Yoichi Takakusagi, Keisuke Saito, Nobu Oshima, Hiroshi Ishikita, Kazutoshi Yamamoto, Murali C. Krishna, Shinsuke Sando
Sci. Adv. 2022, 8, eabj2667. DOI: 10.1126/sciadv.abj2667
[2] "Evaluation of enzymatic and magnetic properties of γ-glutamyl-[1-13C]glycine and its deuteration toward longer retention of the hyperpolarized state"
Yohei Kondo, Yutaro Saito, Abdelazim Elsayed Elhelaly, Fuminori Hyodo, Tatsuya Nishihara, Marino Itoda, Hiroshi Nonaka, Masayuki Matsuo, Shinsuke Sando
RSC Adv. 2021, 11, 37011–37018. DOI: 10.1039/D1RA07343E
[1] Review "Design of nuclear magnetic resonance molecular probes for hyperpolarized bioimaging"
Yohei Kondo, Hiroshi Nonaka, Yoichi Takakusagi, Shinsuke Sando
Angew. Chem. Int. Ed. 2021, 60, 14779–14799. DOI: 10.1002/anie.201915718
[Invited Talks]
[2] October 23rd, 2024, "Development of oligopeptide DNP MRI molecular probes for in vivo studies", Quantum Innovation 2024
[1] September 20th, 2024, "Development of oligopeptide MRI molecular probes for hyperpolarized in vivo bioimaging", The 52nd Annual Meeting of the Japanese Society for Magnetic Resonance in Medicine
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