KONDO Yohei, Ph.D.
:ykondo[at]bio.titech.ac.jp

Research field: Chemical biology

Research keyword: Molecular imaging, Molecular probe, Photochemistry, Nulcear magnetic resonance (NMR), Dynamic nulear polarization (DNP)

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ORCID: 0000-0003-2750-6661

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  [Education]

2009–2012: Tokyo Metropolitan Nishi High School

2013–2015: Natural ScienceⅠ, College of Arts and Sciences, The University of Tokyo

2015–2017: Department of Chemistry and Biotechnology, School of Engineering, The University of Tokyo

2017–2022: Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo (Prof. Shinsuke Sando)

2018–2022: World-leading Innovative Graduate Study program for Materials Research, Information, and Technology(MERIT-WINGS)


 [Work Experience]

2019–2022: JSPS Research Fellowship for Young Scientists(DC1)

2022–2023: Researcher, Mitsubishi Research Institute

2023–Current: Assistant Professor, School of Life Science and Technology, Department of Life Science and Technology, Tokyo Institute of Technology (Prof. Kiyohiko Kawai)

[Publications]

[4] "Structure-guided design enables development of a hyperpolarized molecular probe for the detection of aminopeptidase N activity in vivo"

Yutaro Saito, Hiroyuki Yatabe, Iori Tamura, Yohei Kondo, Ryo Ishida, Tomohiro Seki, Keita Hiraga, Akihiro Eguchi, Yoichi Takakusagi, Keisuke Saito, Nobu Oshima, Hiroshi Ishikita, Kazutoshi Yamamoto, Murali C. Krishna, Shinsuke Sando

Sci. Adv. 2022, 8, eabj2667. DOI: 10.1126/sciadv.abj2667


[3] "Structure-based relaxation analysis reveals C-terminal [1-13C]glycine-d2 in peptides has long spin-lattice relaxation time that is applicable to in vivo hyperpolarized magnetic resonance studies"

Yohei Kondo, Yutaro Saito, Tomohiro Seki, Yoichi Takakusagi, Jumpei Morimoto, Hiroshi Nonaka, Koichiro Miyanishi, Wataru Mizukami, Makoto Negoro, Abdelazim Elsayed Elhelaly, Fuminori Hyodo, Masayuki Matsuo, Natarajan Raju, Rolf Swenson, Murali C. Krishna, Kazutoshi Yamamoto, Shinsuke Sando

ChemRxiv 2022, DOI: 10.26434/chemrxiv-2022-tfkk1


[2] "Evaluation of enzymatic and magnetic properties of γ-glutamyl-[1-13C]glycine and its deuteration toward longer retention of the hyperpolarized state"

Yohei Kondo, Yutaro Saito, Abdelazim Elsayed Elhelaly, Fuminori Hyodo, Tatsuya Nishihara, Marino Itoda, Hiroshi Nonaka, Masayuki Matsuo, Shinsuke Sando

RSC Adv. 2021, 11, 37011–37018. DOI: 10.1039/D1RA07343E


[1] Review "Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging"

Yohei Kondo, Hiroshi Nonaka, Yoichi Takakusagi, Shinsuke Sando

Angew. Chem. Int. Ed. 2021, 60, 14779–14799. DOI: 10.1002/anie.201915718