Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion.

Kukreja* B, Jeon S*, Cao W, Rusu B, Harrison C, Ghazisaeidi S, Tahmasian N, Feng M, Chan R, Loan A, Johnston WB, Padhy S, Rakoff-Nahoum S, Wang J, Yim YS#, and Kalish B# (* co-first author, # co-corresponding author)

Nat Neurosci 2026 29, 732–745 (2026). https://doi.org/10.1038/s41593-025-02162-3

IL-17a promotes sociability in mouse models of neurodevelopmental disorders.

Reed MD*, Yim YS*, Wimmer RD, Kim H, Ryu C, Welch GM, Andina M, King HO, Waisman A, Halassa MM, Huh JR, Choi GB.

Nature. 2020 Jan;577(7789):249-253. doi: 10.1038/s41586-019-1843-6. Epub 2019 Dec 18.

Reversing behavioural abnormalities in mice exposed to maternal inflammation.

Yim YS, Park A, Berrios J, Lafourcade M, Pascual LM, Soares N, Yeon Kim J, Kim S, Kim H, Waisman A, Littman DR, Wickersham IR, Harnett MT, Huh JR, Choi GB.

Nature. 2017 Sep 28;549(7673):482-487. doi: 10.1038/nature23909. Epub 2017 Sep 13.

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring.

Choi GB*, Yim YS*, Wong H*, Kim S, Kim H, Kim SV, Hoeffer CA, Littman DR, Huh JR.

Science. 2016 Feb 26;351(6276):933-9. doi: 10.1126/science.aad0314. Epub 2016 Jan 28.

Spatial transcriptomics of the developing mouse brain immune landscape reveals effects of maternal immune activation and microbiome depletion.

Kukreja* B, Jeon S*, Cao W, Rusu B, Harrison C, Ghazisaeidi S, Tahmasian N, Feng M, Chan R, Loan A, Johnston WB, Padhy S, Rakoff-Nahoum S, Wang J, Yim YS#, and Kalish B# (* co-first author, # co-corresponding author)

Nat Neurosci 2026 29, 732–745 (2026). https://doi.org/10.1038/s41593-025-02162-3

IL-1b and TNF-a-driven sleep alterations: Neuroimmune mechanisms and behavioral implications

Zhang N, Park KS, Chung S, Yim YS

Brain, Behavior, & Immunity-Health 2025 Nov 6:50:101139. doi: 10.1016/j.bbih.2025.101139. eCollection 2025 Dec

Unveiling the enigma of Brain-resident immune cells

Sunsook Hwang, Juneil Jang, Kyungsoo Park, Yeong Shin Yim 

BioRxiv. 2023. doi.org/10.1101/2023.09.26.559602

Adaptive and multifunctional hydrogel hybrid probes for long-term sensing and modulation of neural activity.

Park S, Yuk H, Zhao R, Yim YS, Woldeghebriel EW, Kang J, Canales A, Fink Y, Choi GB, Zhao X, Anikeeva P.

Nat Commun. 2021 Jun 8;12(1):3435. doi: 10.1038/s41467-021-23802-9.

Maternal immune activation in mice disrupts proteostasis in the fetal brain.

Kalish BT, Kim E, Finander B, Duffy EE, Kim H, Gilman CK, Yim YS, Tong L, Kaufman RJ, Griffith EC, Choi GB, Greenberg ME, Huh JR.

Nat Neurosci. 2021 Feb;24(2):204-213. doi: 10.1038/s41593-020-00762-9. Epub 2020 Dec 23.

IL-17a promotes sociability in mouse models of neurodevelopmental disorders.

Reed MD, Yim YS, Wimmer RD, Kim H, Ryu C, Welch GM, Andina M, King HO, Waisman A, Halassa MM, Huh JR, Choi GB.

Nature. 2020 Jan;577(7789):249-253. doi: 10.1038/s41586-019-1843-6. Epub 2019 Dec 18.

Differential mGluR5 expression in response to the same stress causes individually adapted hippocampal network activity.

Yim YS, Han W, Seo J, Kim CH, Kim DG.

Biochem Biophys Res Commun. 2018 Jan 1;495(1):1305-1311. doi: 10.1016/j.bbrc.2017.11.172. Epub 2017 Nov 27.

Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.

Kim S, Kim H, Yim YS, Ha S, Atarashi K, Tan TG, Longman RS, Honda K, Littman DR, Choi GB, Huh JR.

Nature. 2017 Sep 28;549(7673):528-532. doi: 10.1038/nature23910. Epub 2017 Sep 13.

Reversing behavioural abnormalities in mice exposed to maternal inflammation.

Yim YS, Park A, Berrios J, Lafourcade M, Pascual LM, Soares N, Yeon Kim J, Kim S, Kim H, Waisman A, Littman DR, Wickersham IR, Harnett MT, Huh JR, Choi GB.

Nature. 2017 Sep 28;549(7673):482-487. doi: 10.1038/nature23909. Epub 2017 Sep 13.

Relationships between Psychosocial Difficulties and Oxidative Stress Biomarkers in Women Subject to Intimate Partner Violence.

Kim JY, Lee JH, Song HJ, Kim DG, Yim YS.

Health Soc Work. 2017 Feb 1;42(1):41-47. doi: 10.1093/hsw/hlw053.

One-step optogenetics with multifunctional flexible polymer fibers.

Park S, Guo Y, Jia X, Choe HK, Grena B, Kang J, Park J, Lu C, Canales A, Chen R, Yim YS, Choi GB, Fink Y, Anikeeva P.

Nat Neurosci. 2017 Apr;20(4):612-619. doi: 10.1038/nn.4510. Epub 2017 Feb 20.

Molecular signatures of neural connectivity in the olfactory cortex.

Diodato A, Ruinart de Brimont M, Yim YS, Derian N, Perrin S, Pouch J, Klatzmann D, Garel S, Choi GB, Fleischmann A.

Nat Commun. 2016 Jul 18;7:12238. doi: 10.1038/ncomms12238.

The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring.

Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, Hoeffer CA, Littman DR, Huh JR.

Science. 2016 Feb 26;351(6276):933-9. doi: 10.1126/science.aad0314. Epub 2016 Jan 28.

Oxytocin Mediates Entrainment of Sensory Stimuli to Social Cues of Opposing Valence.

Choe HK, Reed MD, Benavidez N, Montgomery D, Soares N, Yim YS, Choi GB.

Neuron. 2015 Jul 1;87(1):152-63. doi: 10.1016/j.neuron.2015.06.022.

Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases.

Yim YS, Kwon Y, Nam J, Yoon HI, Lee K, Kim DG, Kim E, Kim CH, Ko J.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4057-62. doi: 10.1073/pnas.1209881110. Epub 2013 Jan 23.

Hippocampal mGluR5 predicts an occurrence of helplessness behavior after repetitive exposure to uncontrollable stress.

Yim YS, Lee J, Kim GT, Song T, Kim CH, Kim DG.

Neurosci Lett. 2012 Jun 21;519(1):62-6. doi: 10.1016/j.neulet.2012.05.022. Epub 2012 May 14.

A facile approach for the delivery of inorganic nanoparticles into the brain by passing through the blood-brain barrier (BBB).

Yim YS, Choi JS, Kim GT, Kim CH, Shin TH, Kim DG, Cheon J.

Chem Commun (Camb). 2012 Jan 4;48(1):61-3. doi: 10.1039/c1cc15113d. Epub 2011 Nov 7.

Gap junctions contribute to astrocytic resistance against zinc toxicity.

Lee J, Yim YS, Ko SJ, Kim DG, Kim CH.

Brain Res Bull. 2011 Nov 25;86(5-6):314-8. doi: 10.1016/j.brainresbull.2011.08.011. Epub 2011 Aug 22.

Autocrine function of erythropoietin in IGF-1-induced erythropoietin biosynthesis.

Kim I, Kim CH, Yim YS, Ahn YS.

Neuroreport. 2008 Nov 19;19(17):1699-703. doi: 10.1097/WNR.0b013e32831743fb.