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Research
Research
Research theme
Research theme
Biomaterials (Hydrogels/Gels and Nanomaterials); Drug Delivery (Chemotherapeutic Agents, Antidiabetic Drugs, Antibiotics, Anti-inflammatory Drugs, and Microbicide) ; Antibacterial; Wound Healing; and Bone tissue regeneration.
Research
Research
Our research efforts are focused on the development and evaluation of polymer or peptide-based hydrogels/gels, nanomaterials, and bioconjugates for chemotherapeutic agent delivery, antidiabetic drug delivery, anti-inflammatory drug delivery, antibiotic delivery, medical device-associated infection, wound healing, and bone tissue engineering applications.
Antibacterial, self-assembled peptide gels were developed with enhanced proteolytic stability for medical devise associated infections (Biomacromolecules 2018, 19, 782).
Self-healing, injectable, and biodegradable polymeric hydrogels were developed for the pH-responsive sustained release of chemotherapy and 3D cell culture (ACS Applied Materials and Interfaces 2018, 10, 30936).
Self-assembled peptide gels were developed with high proteolytic stability and potent antibacterial activities for medical device-associated infections (ACS Biomaterials Science and Engineering 2020, 6, 5507).
Thiolated mesoporous silica nanoparticles were developed for bone regeneration in osteoporotic conditions (ACS Biomaterials Science and Engineering 2023, 9, 3535).
Antioxidant, self-assembled peptide gels were developed for the pH-responsive, sustained release of glimepiride and to prevent the oxidative stress in diabetic patients (Biomaterials Science 2022, 10, 2248).
Heterogenous catalyst was developed by immobilizing the self-assembling peptide on ceria nanoparticles to mimic the activities of esterase, phosphatase, and halo peroxidase enzymes for industrial applications (Nanoscale 2024, 16, 16887).
Acemannan-coated, cobalt-doped biphasic calcium phosphate nanoparticles were developed to induce bone tissue regeneration and create a pro-healing microenvironment for regeneration (Biomaterials Science 2024, 12, 3672).
Yttrium oxide nanoparticle-loaded, self-assembled peptide gels were developed to inhibit inflammation and bacterial infection, and induce angiogenesis in chronic wounds (ACS Biomaterials Science and Engineering 2023, 9, 2647).
Collaborators
Collaborators
Prof. Anjali Aggarwal, Department of Anatomy, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh
Dr. C M Nagaraja, Department of Chemistry, Indian Institute of Technology Ropar, Rupnagar
Dr. Durba Pal, Department of Biomedical Engineering, Indian Institute of Technology Ropar, Rupnagar
Dr. Garima Agrawal, School of Chemical Sciences, Indian Institute of Technology Mandi, Mandi
Prof. Inderbir Singh, Department of Pharmaceutics, College of Pharmacy, Chitkara University, Rajpura
Dr. Rajendra Srivastava, Department of Chemistry, Indian Institute of Technology Ropar, Rupnagar
Dr. Rajkishor Rai, CSIR - Indian Institute of Integrative Medicine, Jammu
Dr. Rajesh V. Nair, Department of Physics, Indian Institute of Technology Ropar, Rupnagar
Dr. Venkata Krishnan, School of Chemical Sciences, Indian Institute of Technology Mandi, Mandi
Grants
Grants
India-Taiwan Program of Cooperation in Science and Technology, Global Innovation and Technology Alliance (GITA), DST, India (Indian PI: Dr. Yashveer Singh; Taiwanese PI: Prof. Hsin-Chieh Lin, Department of Materials Science and Engineering, National Chiao Tung University (NCTU), Hsinchu, Taiwan), 2023-2026
DBT, India (PI: Dr. Yashveer Singh, co-I: Dr. Durba Pal), 2021-2024
Newton Fund- Researcher Links Workshop Grant 2017, British Council, UK (UK applicant: Prof. Phil Stephens, Cardiff University, Cardiff, UK, Indian applicant: Dr. Yashveer Singh), 2017
SERB, India (PI: Dr. Yashveer Singh), 2017-2020
CSIR, India (PI: Dr. Yashveer Singh), 2016-2018
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