Soft Bioelectronics for Personalized and Precision Healthcare
Soft Bioelectronics for Personalized and Precision Healthcare
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Wearable and implantable bioelectronics represent a transformative approach to healthcare by enabling real-time monitoring of physiological signals and biochemical markers. These devices have the potential to shift healthcare from reactive treatments to proactive, personalized care by providing continuous, non-invasive health monitoring. However, the integration of rigid electronics with the soft, dynamic nature of biological tissues presents notable challenges, requiring innovative materials and scalable manufacturing techniques. Our research focuses on overcoming these challenges to develop soft bioelectronics for personalized and precision healthcare. We aim to create next-generation wearable and implantable systems that can seamlessly integrate with biolgoical tissues, providing continuous tracking of vital signs and biochemical markers.
Theme I. Materials innovations
Theme I. Materials innovations
Proc. Natl. Acad. Sci. U.S.A. 117, 205-213 (2020).
Nat. Nanotechnol. 19, 1158-1167 (2024).
Sci. Adv. 9, eadf0575 (2023); PNAS 117, 18292 (2020).
Traditional healthcare technologies rely on bulky, rigid electronics that are incompatible with the soft and dynamic nature of human tissue. Our research seeks to develop soft, stretchable materials that interface more effectively with biological systems. These materials include stretchable organic conductors, hydrogels, and elastomer composites designed to withstand the mechanical stress and deformation that occurs when worn on or inside the body.
Theme II. Advanced manufacturing
Theme II. Advanced manufacturing
Lithography-based manufacturing methods are limited by their complexity and cost, making them unsuitable for producing large quantities of wearable electronics. Our research sought to address this challenge by exploring scalable, additive manufacturing technologies such as laser scribing and solution-based printing techniques, including inkjet printing and extrusion printing. These methods provide the flexibility and scalability required to produce customizable, high-throughput devices.
Theme III. Multimodal biomedical devices for personalized and precision healthcare
Theme III. Multimodal biomedical devices for personalized and precision healthcare
The next generation of wearable bioelectronics will not only monitor physical health parameters but also provide real-time biochemical data that can inform personalized treatment strategies. Our research focuses on developing multimodal bioelectronic systems that integrate multiple sensing modalities—biophysical (e.g., heart rate, skin temperature) and biochemical (e.g., sweat biomarkers)—into a single device. These systems enable comprehensive health monitoring, offering deeper insights into an individual’s physiological state.
Broader Impact
Broader Impact
Our research program is designed to impact healthcare at multiple levels, from improving the patient experience to enabling new diagnostic and therapeutic strategies. By focusing on the intersection of materials science, mechanical engineering, chemical engineering, and bioengineering, our work aims to create practical solutions that address real-world healthcare challenges. We are particularly interested in developing bioelectronics that can be used in low-resource settings, where traditional healthcare infrastructure may be limited. The cost-effective, scalable nature of the technologies we are developing makes them well-suited for deployment in underserved communities, providing access to advanced health monitoring and diagnostics.
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