From Biomolecular Engineering to Biochemical Systems Engineering

Artificial metalloenzymes (ArMs), which can be constructed by incorporating a synthetic metal complex into a protein matrix, are my main research interests. Thus, my research includes 

(1) development of synthetic catalysts as an abiotic cofactor of artificial metalloenzyme, 

(2) protein engineering to optimize reaction environment (e.g. hydrophobicity, chirality etc...)

(3) construction of artificial metalloenzymes with a developed abiotic cofactor and an engineered protein

(4) designing catalysis systems composed of natural/artificial enzymes for multistep chemical transformation in one pot or construction of out-of-equilibrium system.