Xingjian Zhang
Xingjian Zhang
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Harvard Medical School & Massachusetts General Hospital
Office Address:
100 Blossom St, Boston, MA, 02114
About Me and My Research
I am a Research Fellow at Harvard Medical School and Massachusetts General Hospital, working under the co-mentorship of Dr. Rakesh Jain and Dr. Lance Munn. My research focuses on addressing critical challenges in immuno-oncology from a biophysical perspective. I specializes in engineering immune cells to overcome the biophysical barriers of the tumor microenvironment, which contribute to cancer immune evasion. My goal is to improve immunotherapy for solid tumors, providing better treatment options and survival outcomes for patients resistant to current therapies.
Research Positions
Research Fellow | 2024-Present
Harvard Medical School & Massachusetts General Hospital
Advisors: Rakesh Jain, PhD and Lance Munn, PhD
Collaborators: Mario L Suvà, MD, PhD, Brian Seed, PhD
Education
Yale University
Ph.D. | Biomedical Engineering | 2017-2023
Advisor: Michael Mak, PhD
PhD Committee: Rong Fan, PhD | Kathryn Miller-Jensen, PhD | Andre Levchenko, PhD
Collaborators: Gerald Shadel, PhD | Marcus Bosenberg, MD, PhD | Farzana Pashankar, MD, MRCP, MBBS
Fundings
2025 Mass General Neuroscience Transformative Scholar Award
($150, 000 non-fellowship funding, Harvard Medical School & Mass General Hospital)
2021 Yale University Frederic Ewing Fellowship
2020 Yale University Graduate Student Assembly Conference Travel Fellowship
2017 Columbia-Coulter Foundation Angel Investment (Columbia University)
Honors and Awards
2025 James L. and Elisabeth C. Gamble Fellow (Harvard Medical School & Mass General Hospital)
2025 Nominated for MGH "Outstanding Research Fellow Mentor Award"
2024 Biophysical Society - Physical Cell Biology Student Award
2021- Yale University Advanced Graduate Leadership Program (AGLP) Fellow
Academic Services
Peer-reviewed for journals
Communications Biology | Biofabrication | APL Bioengineering | Bioinformatics Advances | Biophysical Journal | Physical Biology | International Journal of Biological Sciences | International Journal of Medical Sciences | Journal of Cancer
Media Reports
2023
"Compression of cancer cells a double-edged sword, study finds" - Yale News
"Cell Compression and Dual Impact on Melanoma" - MirageNews
"Compression of cancer cells is a double-edged sword, study finds" - MedicalXpress
"肿瘤细胞体积压缩是一把双刃剑" - Scientific American-Chinese Edition (环球科学)
2017
"Notable advances 2017" - Nature Medicine
"Researchers Track an Unlikely Culprit in Weight Gain" - New York Times
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