Team

Meet Yang Lab members and affiliating collaborators here!

Accessibility, Respect, and Empowerment

The Yang Lab commits to providing accessibility for everyone to embrace scientific research and education and seeks to create an environment that welcomes and respects people and empowers them to conduct creative and innovative research.

Lab members

Xiaoxu Yang, PhD

Assistant Professor, Department of Human Genetics, University of UtahInvestigator, Utah Center for Genetic DiscoveryMember, Nuclear Control Program, Huntsman Cancer Institute
Xiaoxu is a faculty member at the Department of Human Genetics, Utah Center for Genetic Discovery, and Huntsman Cancer Institute, University of Utah. Xiaoxu received his BS in BioScience from Beijing Normal University with trainings in Dr. Xiaobo Qiu's lab, PhD in Bioinformatics from the Center for Bioinformatics, Peking University, with Dr. Liping Wei, and his Postdoctoral research experiences at the Department of Neurosciences, University of California, San Diego, with Dr. Joseph Gleeson.
Xiaoxu and colleagues developed computational tools such as DeepMosaic, the first Deep-learning-based mosaic variant caller without matched control, and MosaicBase, the first non-cancer mosaic variant knowledge base. He also developed experimental methodologies such as PASM (Postzygotic Amplicon Sequencing for Mosaicism), mddPCR (micro-droplet digital PCR), MPAS (Massive Parallel Amplicon Sequencing), and scMPAS (single-nucleus MPAS), and further integrated them into MVBA (Mosaic Variant Barcode Analyses).
Using these technologies he developed, Xiaoxu and colleagues started the study for sperm mosaic mutations causing childhood neurological and psychiatric disorders. He pioneered the research of non-cancer germline and mosaicism in sperm, brain, and multiple human-derived tissues. He found sperm clonal mosaic mutations causing lifelong transmission risk for normal males. Xiaoxu and colleagues also pioneered using mosaic mutations as developmental markers and first described left-right and dorsal inhibitory brain genetic lineages in normal human cortical development. Xiaoxu and team found mosaicism as the cause for multiple human disease such as malformations of cortical development. Read more on Linkedin

Muhammad Zubair, PhD

Postdoctoral Researcher
Muhammad received a PhD in Biological Science from the University of Science and Technology of China. Muhammad's research interest is the mechanisms for male infertility. Read more on Google Scholar

Ian Graham

Lab Specialist
Ian received a bachelor's degree in Neuroscience from Lawrence University. Ian continued as a Laboratory Assistant in Progenitor, Lawrence University, and Diabetes and Endocrine Specialists. Read more on Linkedin.

Sai Babu Patarlapalli, MS

Bioinformatic Analyst
Sai received a master's degree in Applied Data Science from Clarkson University and Bachelor of Technology from Godavari Institute of Engineering and Technology. Sai worked as Engineer for three years in Panther MotoCrop, ARBL, and Tata Technologies in data analysis, code development, and AI integration across industrial and academic settings. Read more on LinkedIn

Xincen Xi, MD

Graduate Researcher
Xincen received a bachelor's degree in Clinical Medicine from Yang Zhou University and MD and MS in Obstetrics and Gynecology from Tongji University. Xincen also received an MS in Biomedical Informatics at the University of Utah and is now a first-year student in the Molecular Biology PhD program at the University of Utah. Read more on LinkedIn.

Margot Lockwood

Graduate Researcher
Margot received bachelor's degree in Physics from the University of Kansas and Harvey Mudd College. Margot then continued as a DOE research student at Pacific Northwest National Laboratory. Margot is a first-year student in the Molecular Biology PhD program at the University of Utah. Read more on LinkedIn.

Ruben Ratulangi Sundramrti

Undergraduate volunteer
Ruben is currently an undergrad in Psychology at the University of Utah before transferring from the University of Iowa Engineering. Read more on LinkedIn.

Kate Pache, MS

Joint Graduate Student
Kate received a master's degree in Physiology and Neurobiology from the University of Connecticut. She is currently a joint PhD student in Embryology at Eastern Virginia Medical School and an Embryologist at the Fertility Specialists Medical Group. Read more on LinkedIn

Yang Liu

Joint Graduate Student
Yang received a bacholar's degree in Cellular and Molecular Biology from the University of California, San Diego. Yang is currently a joint PhD student at the University of Southern California. Read more on LinkedIn

Alumni

Sang Hyun Lee, 2024 - 2025, Analyst (Current: Graduate student at Johns Hopkins University)

John Prevedel, 2024, MBP Rotation Student (Current: Graduate student in Jamie Gagnon's lab at the University of Utah)

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