The highest level protein processing

The rapid progress of molecular cell biology has created a need for structural biologists to look at increasingly more complex protein structures. These usually require particular post-translational modifications and co-factors to support their elaborate folding and enzymatic activity.

Mammalian expression system exhibits the highest level of protein processing, which is important for complete biological activity. It is widely used for the production of recombinant glycoproteins (vaccines, enzymes) as well as hormones and immunobiologicals (antibodies, interleukins, lymphokines), as they have the advantage of full post-translational modifications of the expressed protein (e.g. proper folding, glycosylation, phosphorylation, etc) .

However, mammalian cell expression can be a challenging task given the expertise needed , so the cost is higher and achieving large amounts of protein (>10mg) may be difficult.

BiologicsCorp has decades of experience and expertise in both transient and stable expression based on HEK293 or CHO cell lines. Our advanced mammalian cell platform comprises improved promoters, signal sequences, vectors and transfection procedures. Additional yield enhancement through better expression and purification strategies further improves cost efficiency for the recombinant proteins. You simply provide the target protein sequence and we will deliver the protein at the amount and purity that you specified.

Need more information? Please do not hesitate to contact us !

( view details : mammalian cell protein expression)