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Blinking & Super-Resolved Imaging
Blinking & Super-Resolved Imaging
By overcoming the diffraction limit of light, super-resolution imaging can elucidate biological and materials structures and processes at unprecedented resolution. Many super-resolution approaches require single molecules that undergo "blinking" between emissive (on) and non-emissive (off) events. We develop and apply a new "blink-based multiplexing" approach to multicolor super-resolution imaging. Machine learning is used to support the experiments.
Recent article: https://pubs.acs.org/doi/full/10.1021/acs.jpclett.2c01252
Art Conservation
Art Conservation
Owing to its exquisite sensitivity and selectivity, surface-enhanced Raman spectroscopy (SERS) is increasingly used to study cultural heritage objects. In collaboration with the paintings conservation lab at Colonial Williamsburg and the Philadelphia Museum of Art, we develop and apply SERS-based methods to identify fugitive (fading) pigments in precious works of art.
Recent article: https://www.tandfonline.com/doi/abs/10.1080/00393630.2021.1961391
Solar Energy Conversion
Solar Energy Conversion
Electron transfer (ET) processes dictate the efficiency of materials and devices that are used to harness solar energy. We investigate ET processes in organic-based materials for solar energy conversion using single-molecule fluorescence. Robust statistical analysis and computational modeling support the experiments.
Recent article: https://pubs.acs.org/doi/full/10.1021/acs.jpcc.1c07597
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