Change point detection (CPD) algorithm for binned blinking data. Source code available at GitLab through the Wustholz Lab repository at https://gitlab.com/wustholz-lab/binned-change-point-detection
Please cite the following reference: Kopera, K. M; Tuckman, H. R.; Hoy, G. R.; Wustholz, K. L. Origin of Kinetic Dispersion in Eosin-Sensitized TiO2: Insights from Single-Molecule Spectroscopy, J. Phys. Chem. C 2021, 125, 43, 23634–23645.
Independent career referreed publications, William & Mary students in bold
Wustholz, K. L.; Svoboda, S. A.; Martin, M.G.; Steinman, B.T.; Zheng, Z. Uncovering Art’s Vanishing Hues with SERS: Drawing Inspiration from the Past for the Future, ACS Nano, published online June 2024. https://doi.org/10.1021/acsnano.4c05389
Table of contents artwork by Meredith Martin
Seabury, A. G.; Khodabocus, A. J.; Kogan, I. M.; Hoy, G. R.; DeSalvo, G. A.; Wustholz, K. L. , Blinking characteristics of organic fluorophores for blink-based multiplexing. Commun. Chem., 2024, 7 (18), 1-12.
The change point detection method for binned data used to analyze blinking dynamics for this study is available at zenodo.org: https://doi.org/10.5281/zenodo.10471846
Hoy, G. R.; DeSalvo, G. A.; Haile, S. H.; Smith, E. N.; Wustholz, K. L. Rapid, Accurate Classification of Single Emitters in Various Conditions and Environments for Blinking-Based Multiplexing, J. Phys. Chem. A, 2023, 127, 3518-3525.
DeSalvo, G. A.; Hoy, G. R.; Kogan, I. M.; Li, J. Z.; Palmer, E. T.; Luz-Ricca, E.; Scemama de Giaully, P.; Wustholz, K. L. Blinking-Based Multiplexing: A New Approach for Differentiating Spectrally-Overlapped Emitters, J. Phys. Chem. Lett., 2022, 13, 5056-5060.
Eisnor, M.M.; McLeod, K.E.R.; Bindesri, S.; Svoboda, S.A.; Wustholz, K. L.; Brosseau, C. L. Electrochemical surface-enhanced Raman spectroscopy (EC-SERS): a tool for the identification of polyphenolic components in natural lake pigments, Phys. Chem. Chem. Phys. 2022, 24, 347-356.
Kopera, K. M; Tuckman, H. R.; Hoy, G. R.; Wustholz, K. L. Origin of Kinetic Dispersion in Eosin-Sensitized TiO2: Insights from Single-Molecule Spectroscopy, J. Phys. Chem. C 2021, 125, 43, 23634–23645.
Choffel, M.A.; Farling, C. G.; Frano, K.A.; Matecki, M.K., Zheng, Z.; Svoboda, S.A.; Wustholz, K. L. Revealing the Fugitive Palette of the Early American South: A SERS Study of Eighteenth-century Oil Paintings, Studies in Conservation, 2022, 67, 556-568.
Lynch, P. G.; Richards, H.; Wustholz, K. L. Unraveling the Excited-State Dynamics of Eosin Y Photosensitizers Using Single-Molecule Spectroscopy, J. Phys. Chem. A, 2019, 123 (13), 2592–2600.
Farling, C. G.; Fikse, K. M.; Svoboda, S. A.; Wustholz, K. L. "Development of a quality assurance protocol for SERS-based identification of organic pigments in art," Opt. Mater. Express, 2019, 9(3), 1513-1519. (Invited original manuscript for themed issue on Design, Manufacture, and Analysis of Photonic Materials for Historical and Modern Visual Arts)
Burke, S. N.; Farling, C. G.; Svoboda, S. A.; Wustholz, K. L. Research with Undergraduates at the Intersection of Chemistry and Art: Surface-Enhanced Raman Scattering Studies of Oil Paintings. In Raman Spectroscopy in the Undergraduate Curriculum; Sonntag, M.D., Ed.; ACS Symposium Series 1305; American Chemical Society: Washington, DC, 2018; pp. 165-180.
Cassidy, J. P.; J. A. Tan, J. A.; Wustholz, K. L. Probing the Aggregation and Photodegradation of Rhodamine Dyes on TiO2, J. Phys. Chem. C, 2017, 121 (29), 15610–15618.
J. A. Tan, S. Garakyaraghi, K. A. Tagami, K. A. Frano, H. M. Crockett, A. F. Ogata, J. D. Patterson, K. L. Wustholz, Contributions from Excited-State Proton and Electron Transfer to the Blinking and Photobleaching Dynamics of Alizarin and Purpurin, J. Phys. Chem. C, 2017, 121(1), 97-106.
B. Roark, J. A. Tan, A. Invanina, M. Chandler, J. Castaneda, H. S. Kim, S. Jawahar, M. Viard, S. Talic, K. L. Wustholz, Y. G. Yingling, M. Jones, K. Afronin, Fluorescence Blinking as an Output Signal for Biosensing, ACS Sensors, 2016, 1 (11), 1295-1300.
J. A. Tan, J. T. Rose, J. P. Cassidy, S. K. Rohatgi, K. L. Wustholz, Dispersive Electron-Transfer Kinetics of Rhodamines on TiO2: Impact of Structure and Driving Force on Single-Molecule Photophysics, J. Phys. Chem. C, 2016, 120, 20710-20720.
J.-Y. Roh, M. K. Matecki, S. A. Svoboda, K. L. Wustholz, Identifying Pigment Mixtures in Art using SERS: A Treatment Flowchart Approach, Anal. Chem. 2016, 88 (4), 2028-2032.
J. M. Blake-Hedges, S. H. Greenspan, J. A. Kean, M. A. McCarron, M. L. Mendonca K. L. Wustholz, Plasmon-Enhanced Fluorescence of Dyes on Silica-Coated Silver Nanoparticles: A Single-Nanoparticle Spectroscopy Study, Chem. Phys. Lett. 2015, 635, 328-333.
H. E. Mayhew, K. A. Frano, S. A. Svoboda, K. L. Wustholz, Using Raman Spectroscopy and Surface-Enhanced Raman Scattering to Identify Colorants in Art: an Experiment for an Upper-Division Chemistry Laboratory, J. Chem. Educ. 2015, 92 (1), 148-152.
K. A. Frano, H. E. Mayhew, S. A. Svoboda, K. L. Wustholz, Combined SERS and Raman Analysis for the Identification of Red Pigments in Cross-Sections from Historic Oil Paintings, Analyst, 2014, 139, 6450-6455.
N. Z. Wong, A. F. Ogata, K. L. Wustholz, Dispersive Kinetics from Single Emitters on TiO2 Nanoparticle Films, J. Phys. Chem. C, 2013, 117 (41), 21075-21085.
H. E. Mayhew, D. M. Fabian, S. A. Svoboda, K. L. Wustholz, Surface-Enhanced Raman Spectroscopy Studies of Yellow Organic Dyestuffs and Lake Pigments in Oil Paint, Analyst, 2013, 138 (16), 4493-4499.
L. H. Oakley, D. M. Fabian, H. E. Mayhew, S. A. Svoboda, K. L. Wustholz, Pretreatment Strategies for SERS Analysis of Indigo and Prussian Blue in Aged Painted Surfaces, Anal. Chem. 2012, 84, 8006-8012.
L. H. Oakley, S. A. Dinehart, S. A. Svoboda, K. L. Wustholz, Identification of Organic Materials in Historic Oil Paintings Using Correlated Extractionless Surface-Enhanced Raman Scattering and Fluorescence Microscopy, Anal. Chem. 2011, 83, 3986-3989.