32. Host metabolism balances microbial regulation of bile acid signaling.

Tae Hyung Won#, Mohammad Arifuzzaman#, Christopher N. Parkhurst#, Isabella C. Miranda, Bingsen Zhang, Elin Hu, Sanchita Kashyap, Jeffrey Letourneau, Wen-Bing Jin, Yousi Fu, Douglas V. Guzior, JRI Live Cell Bank, Robert A. Quinn, Chun-Jun Guo, Lawrence A. David, David Artis*, and Frank C. Schroeder*. Nature, (2025).

31. Dietary fiber is a critical determinant of pathologic ILC2 responses and intestinal barrier inflammation.

Mohammad Arifuzzaman, Tae Hyung Won, Hiroshi Yano, Jazib Uddin, Elizabeth R. Emanuel, Elin Hu, Wen Zhang, Tingting Li, Wen-Bing Jin, Alex Grier, Sanchita Kashyap, JRI Live Cell Bank, Chun-Jun Guo, Frank C. Schroeder, and David Artis*. Journal of Experimental Medicine, 221, e20232148 (2024).

30. Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation.

Mohammad Arifuzzaman, Tae Hyung Won, Tingting Li, Hiroshi Yano, Sreehaas Digumarthi, Andrea F. Heras, Wen Zhang, Christopher N. Parkhurst, Sanchita Kashyap, Wen-Bing Jin, Gregory Garbès Putzel, Amy Tsou, Coco Chu, Qianru Wei, Alex Grier, JRI Live Cell Bank, Stefan Worgall, Chun-Jun Guo*, Frank C. Schroeder*, and David Artis*. Nature, 611, 578-584 (2022).

29. Copper starvation induces antimicrobial isocyanide integrated into two distinct biosynthetic pathways in fungi.

Tae Hyung Won, Jin Woo Bok, Nischala Nadig, Nandhitha Venkatesh, Grant Nickles, Claudio Greco, Fang Yun Lim, Jennifer B. González, B. Gillian Turgeon, Nancy P. Keller*, and Frank C. Schroeder*. Nature Communications, 13, 4828 (2022).

28. Psammocindoles A-C: Isolation, Synthesis, and Bioactivity of Indole-γ-lactams from the Sponge Psammocinia vermis.

Oh-Seok Kwon, Sungjin Ahn, Ju-Eun Jeon, In Guk Park, Tae Hyung Won, Chung J Sim, Hyeung-Geun Park, Dong-Chan Oh, Ki-Bong Oh, Minsoo Noh*, and Jongheon Shin*. Organic Letters, 23, 4667-4671 (2021).

27. Dual-purpose isocyanides produced by Aspergillus fumigatus contribute to cellular copper sufficiency and exhibit antimicrobial activity.

Nicholas Raffa, Tae Hyung Won, Andrew Sukowaty, Kathleen Candor, Chengsen Cui, Saayak Halder, Mingji Dai, Julio A Landero-Figueroa, Frank C. Schroeder, and Nancy P Keller*. Proc Natl Acad Sci U S A, 118, e2015224118 (2021).

26. Isocadiolides A–H: Polybrominated Aromatics from a Synoicum sp. Ascidian.

Jongkyoon Bae, Eunji Cho, Jae Sung Park, Tae Hyung Won, Su-Yuan Seo, Dong-Chan Oh, Ki-Bong Oh*, and Jongheon Shin*. Journal of Natural Products, 83, 429-437 (2020).

25. The microbiota regulate neuronal function and fear extinction learning

Coco Chu, Mitchell H. Murdock, Deqiang Jing, Tae Hyung Won, Hattie Chung, Adam M. Kressel, Tea Tsaava, Meghan E. Addorisio, Gregory G. Putzel, Lei Zhou, Nicholas J. Bessman, Ruirong Yang, Saya Moriyama, Christopher N. Parkhurst, Anfei Li, Heidi C. Meyer, Fei Teng, Sangeeta S. Chavan, Kevin J. Tracey, Aviv Regev, Frank C. Schroeder, Francis S. Lee, Conor Liston*, and David Artis*. Nature, 574, 543-548 (2019).

24. The novel strategy for concurrent chemoradiotherapy by conjugating the apoptotic cell-binding moiety to caspase-3 activated doxorubicin prodrug

Young Seok Cho, Seung Woo Chung, Ha Rin Kim, Tae Hyung Won, Jeong Uk Choi, In-San Kim, Sang Yoon Kim*, and Youngro Byun*. Journal of Controlled Release, 296, 241-249 (2019).

23. Highly potent monomethyl auristatin E prodrug activated by caspase-3 for the chemoradiotherapy of triple-negative breast cancer.

Seung Woo Chung, Young Seok Cho, Jeong Uk Choi, Ha Rin Kim, Tae Hyung Won, Sang Yoon Kim*, and Youngro Byun*. Biomaterials, 192, 109-117 (2019).

22. Self‐Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase‐Cleavable Linker

Seung Woo Chung, Jeong Uk Choi, Young Seok Cho, Ha Rin Kim, Tae Hyung Won, Peter Dimitrion, Ok‐Cheol Jeon, Seong Who Kim, In‐San Kim, Sang Yoon Kim*, and Youngro Byun*. Advanced Science, 5, 1800368 (2018).

21. Fungal isocyanide synthases and xanthocillin biosynthesis in Aspergillus fumigatus

Fang Yun Lim#, Tae Hyung Won#, Nicholas Raffa, Joshua A. Baccile, Jen Wisecaver, Antonis Rokas, Frank C. Schroeder, and Nancy P. Keller*. mBio, 9, e00785-18 (2018).

20. Manzamine Alkaloids from an Acanthostrongylophora sp. Sponge

Chang-Kwon Kim, Riswanto Riswanto, Tae Hyung Won, Heegyu Kim, Berna Elya, Chung J. Sim, Dong-Chan Oh, Ki-Bong Oh*, and Jongheon Shin*. Journal of Natural Products, 80, 1575-1583 (2017).

19. Asperphenins A and B, Lipopeptidyl Benzophenones from a Marine-Derived Aspergillus sp. Fungus.

Lijuan Liao, Song Yi Bae, Tae Hyung Won, Minjung You, Seong-Hwan Kim, Dong-Chan Oh, Sang Kook Lee, Ki-Bong Oh*, and Jongheon Shin*. Organic Letters, 19, 2066-2069 (2017).

18. Metabolomic approach for discrimination of four- and six-year-old red ginseng (Panax ginseng) using UPLC-QToF-MS.

Jung-Sub Shin, Hee-Won Park, Gyo In, Hyun Kyu Seo, Tae Hyung Won, Kyoung Hwa Jang*, Byung-Goo Cho, Chang Kyun Han, and Jongheon Shin. Chemical & Pharmaceutical Bulletin, 64, 1298-1303 (2016).

17. Amino acid-derived metabolites from the Ascidian Aplidium sp.

Tae Hyung Won, Chang-Kwon Kim, So-Hyoung Lee, Boon Jo Rho, Sang Kook Lee, Dong-Chan Oh, Ki-Bong Oh*, and Jongheon Shin*. Marine Drugs, 13, 3836-3848 (2015).

16. Determination and validation of psammaplin A and its derivatives in rat plasma by liquid chromatography-tandem mass spectrometry and its application in pharmacokinetic study.

Jae-Young Lee, Mee Yeon Lee, Min Woo Ha, Tae Hyung Won, Hyun-Jong Cho, Jongheon Shin, Hyeung-geun Park, Dae-Duk Kim*. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1000, 155-162 (2015).

15. Bioactive metabolites from the fruits of Psoralea corylifolia.

Tae Hyung Won#, Inn-Hye Song#, Kuk-Hwa Kim, Woo-Young Yang, Sang Kook Lee, Dong-Chan Oh, Won-Keun Oh, Ki-Bong Oh*, and Jongheon Shin*. Journal of Natural Products, 78, 666-673 (2015).

14. Streptococcus mutans sortase A inhibitory metabolites from the flowers of Sophora japonica.

Woo-Young Yang, Tae Hyung Won, Chan-Hong Ahn, So-Hyoung Lee, Hyeong-Cheol Yang, Jongheon Shin*, and Ki-Bong Oh*. Bioorganic Medicinal Chemistry Letters, 25, 1394-1397 (2015).

13. Suvanine Sesterterpenes from a Tropical Sponge Coscinoderma sp. Inhibit Isocitrate Lyase in the Glyoxylate Cycle.

So-Hyoung Lee, Tae Hyung Won, Heegyu Kim, Chan-Hong Ahn, Jongheon Shin*, and Ki-Bong Oh*. Marine Drugs, 12, 5148-5159 (2014).

12. Amino Alcohols from the Ascidian Pseudodistoma sp. 

Tae Hyung Won, Minjung You, So-Hyoung Lee, Boon Jo Rho, Dong-Chan Oh, Ki-Bong Oh*, and Jongheon Shin*. Marine Drugs, 12, 3754-3769 (2014).

11. New Cyclic Cystine Bridged Peptides from the Sponge Suberites waedoensis.

Jinhaeng Song, Ju-eun Jeon, Tae Hyung Won, Chung J. Sim, Dong-Chan Oh, Ki-Bong Oh*, and Jongheon Shin*. Marine Drugs, 12, 2760-2770 (2014).

10. New Benzoxazine Secondary Metabolites from an Arctic Actinomycete.

Kyuho Moon, Chan-Hong Ahn, Yoonho Shin, Tae Hyung Won, Keebeom Ko, Sang Kook Lee, Ki-Bong Oh, Jongheon Shin, Seung-Il Nam, and Dong-Chan Oh*. Marine Drugs, 12, 2526-2538 (2014).

9. Quantification and Identification of Bioactive Metabolites from Kalopanacis Cortex by HPLC with Evaporative Light Scattering Detection and ESI Quadrupole TOF MS.

Lijuan Liao, Tae Hyung Won, Young Ho Kim, and Jongheon Shin*. Journal of Separation Science, 37, 505-514 (2014).

8. Simultaneous Analysis of Furfural Metabolites from Rehmanniae Radix Preparata by HPLC-DAD-ESI-MS.

Tae Hyung Won, Lijuan Liao, Sam Sik Kang, and Jongheon Shin*. Food Chemistry, 142, 107-113 (2014).

7. Inhibition of Candida Albicans Isocitrate Lyase Activity by Cadiolides and Synoilides from the Ascidian Synoicum sp. 

Chan-Hong Ahn, Tae Hyung Won, Heegyu Kim, Jongheon Shin*, and Ki-Bong Oh*. Bioorganic Medicinal Chemistry Letters, 23, 4099-4101 (2013).

6. Brominated Aromatic Furanones and Related Esters from the Ascidian Synoicum sp. 

Tae Hyung Won, Ju-eun Jeon, Seong-Hwan Kim, So-Hyoung Lee, Boon Jo Rho, Dong-Chan Oh, Ki-Bong Oh*, and Jongheon Shin*. Journal of Natural Products, 75, 2055-2061 (2012).

5. Beta-Carboline Alkaloids Derived from the Ascidian Synoicum sp.

Tae Hyung Won, Ju-eun Jeon, So-Hyoung Lee, Boon Jo Rho, Ki-Bong Oh*, and Jongheon Shin*, Bioorganic Medicinal Chemistry, 20, 4082-4087 (2012).

4. Simultaneous Analysis of Bioactive Metabolites from Ziziphus jujuba by HPLC-DAD-ELSD-MS/MS. 

Lijuan Liao, Tae Hyung Won, Sam Sik Kang, and Jongheon Shin*. Journal of Pharmaceutical Investigation, 42, 21-31 (2012).

3. Comparative Analyses of Bioactive Constituents from Forsythia suspensa and Forsythia viridissima by HPLC-DAD. 

Tae Hyung Won, Lijuan Liao, Seung Ho Lee, Jong Keun Son, and Jongheon Shin*. Natural Product Sciences, 17, 328-336 (2011).

2. Simultaneous Analysis of Bioactive Metabolites from Rehmannia glutinosa by HPLC-DAD-MS/MS. 

Tae Hyung Won, Sungkwang Ryu, Sam Sik Kang, and Jongheon Shin*. Natural Product Sciences, 16, 116-122 (2010).

1. Simultaneous Analysis of Bioactive Metabolites from Caulis Lonicera japonica by HPLC-DAD-ion trap-MS. 

Sungkwang Ryu, Tae Hyung Won, Sam Sik Kang, and Jongheon Shin*. Yakhak Hoeji, 54, 157-163 (2010)