Overview
Our group conducts research on bio-chem-analytical microelectronic systems, in situ sensing in complex environments, and integrated micro-nanotechnologies. Our work focuses sensor development, device design, system integration and application innovation, with the aim of advancing analytical technologies toward miniaturization, continuity, automation, and intelligence for applications in healthcare, human–machine interaction, environmental monitoring, and beyond.
Breath analysis microsystem (Smart Mask)
EBCare, a smart mask for continuous, noninvasive analysis of exhaled breath condensate. It integrates passive cooling, microfluidics, electrochemical sensing, and wireless readout to monitor breath biomarkers during normal mask wearing. The system converts breath aerosols and vapors into liquid samples. The platform was demonstrated for monitoring respiratory inflammation, metabolic activity, and disease-related biomarkers in healthy subjects and patients with COPD, asthma, and post-COVID conditions.
EBClite, a self-powered and long-term reusable smart mask for biochemical sensing of exhaled breath condensate. By integrating flexible perovskite photovoltaics, a renewable porous hydrogel condenser, and highly stable electrochemical lactate sensors, It addresses key limitations of EBC monitoring, including power dependence, sampling, and sensor durability. The platform further demonstrates practical applications in tracking exercise- and diet-related metabolic dynamics
Science 385 (6712), 954-961 (2024) Download PDF Science, NIH, NIHLBI, Forbes et al. highlight. ESI Hot Paper (0.1 %)
Nature Sensors 1, 328–340 (2026) Download PDF Nature Sensors, Caltch News et al. highlight.
IEEE Reviews in Biomedical Engineering 18, 50-73 (2024) Download PDF
Human-machine interaction microsystem (CoboSkin)
CoboSkin, a soft robot skin with variable stiffness for safer human–robot collaboration, integrates inflatable pneumatic units with soft porous force-sensing units to provide both tactile perception and collision protection. By regulating internal air pressure, the system actively tunes skin stiffness, enhances sensing sensitivity, and reduces peak impact force during unintended contact. The porous sensing materials provide high sensitivity, low hysteresis, fast response, and excellent cycling stability. The platform further demonstrates practical applications in robotic arm collision detection, force feedback, and safer physical interaction between humans and collaborative robots.
Skin-interfaced Sensors (E-Skin) (contributing)
E-Skin, a kind of soft bioelectronic interfaces for sensing sweat, wound exudate, and other biofluids, integrates conformal microfluidics with flexible biochemical sensors for continuous on-skin analysis. These platforms enable real-time monitoring of hydration, metabolic status, and wound healing for personalized healthcare.
Skin-interfaced breath sensing system (TGP)
TBA