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About Dr. Guo
About Dr. Guo
Dr. Weijie Guo won the gold medal in the National Biology Olympiad of China in 2013 and obtained direct entry to Peking University. He received his B.S. degree in Life Sciences from Peking University in 2018. During his undergraduate period, he was trained as a stem cell biologist in Dr. Hongkui Deng's lab and supervised by Dr. Chengyan Wang. He was recognized as an Outstanding Student Leader in Beijing for his contribution to the department Youth League Committee and won the President's Undergraduate Research Fellowship of Peking University. After graduation, he went to the University of Illinois at Urbana-Champaign to pursue a Ph.D. degree and joined Dr. Yi Lu's lab in 2018. After the qualifying exam, he moved along with Dr. Lu to the University of Texas at Austin. He obtained his Ph.D. in Biochemistry in 2024 from UT Austin. His thesis work focused on non-genetic functions of DNAs, including DNAzymes, DNA aptamers, and functional DNAs in Neutrophil Extracellular Traps.
Now, Dr. Guo is working as a postdoc research fellow in Prof. Arturo Zychlinsky's lab at Max Planck Institute for Infection Biology (Berlin, Germany). Dr. Guo's research interests lie in the interface between chemical biology and immunology. Specifically, he is eager to know the neutrophil extracellular trap's biological properties and functions from a DNA-centric view.
Introduction in Chinese:
郭伟杰博士，现为马克斯普朗克协会感染病研究所博士后，2024年国家优秀自费留学生奖学金获得者。2018年本科毕业于北京大学生命科学学院（导师：邓洪魁）; 2018年至2024年于University of Illinois at Urbana-Champaign和University of Texas at Austin生物化学系Yi Lu实验室攻读并获得博士学位；2024年起于德国马克斯普朗克协会感染病研究所（Max Planck Institute for Infection Biology）Arturo Zychlinsky实验室从事博士后研究工作。郭伟杰博士共发表论文17篇，其中以一作/共同一作在Nature Biotechnology (IF 33.1, 2024), Nature Protocols (IF 13.1, 2025), PNAS (IF 9.4, 2025), ACS Central Science (IF 18.2, 2021) 等国际知名期刊上发表论文4篇，总引用500+，H-index 10，并申请或获批两项国际专利。
郭伟杰博士的研究主要聚焦于核酸分子(DNA和RNA) 的非遗传学功能，先天免疫中细胞外核酸及核酸复合体的复杂生物学功能和与疾病的机理。着重开发和利用新型分子生物学工具，研究：1.细菌感染导致的中性粒细胞染色体重组的分子机制；2. 中性粒细胞细胞外陷阱中的新型DNA-蛋白质相互作用机制；3. 糖基化RNA介导的中性粒细胞-巨噬细胞相互作用机制; 目标实现病理微环境特异性的精准医疗。
Awards
2024 Award for Excellent Self-Sponsored International Students
2024 Travel Award, Texas Chemical Biology Conference, Texas A&M University and Rice University
2023 Best Talk Award, 5th International Graduate Forum of Chemical Biology, Peking University
2023 Best Talk Prize, RNA&DNA Club at Department of Molecular Biosciences, UT Austin
2023 Professional Development Award, Department of Molecular Biosciences, UT Austin
2023 Summer Research Fellowship, Department of Molecular Biosciences, UT Austin
2023 Biological Chemistry Research Award, Division of Biological Chemistry, American Chemistry Society (ACS)
2018 Carr Fellowship, University of Illinois at Urbana-Champaign
2018 Outstanding Student Leader, Beijing
2017 Almari Fellowship, College of Life Sciences, Peking University
2017 President Undergraduate Research Fellowship, Peking University
2013 Gold medal, National Biology Olympiad, China
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