Red and Yellow are anthropomorphic characters introduced in M&M's commercials since the 1960s.

Red is an M&M's character originally voiced by Jon Lovitz who also played the voice of Radio in the first installment of The Brave Little Toaster, but is currently voiced by Billy West, who also voiced Phillip J. Fry in Futurama, and Popeye and Poopdeck Pappy in Popeye's Voyage: The Quest for Pappy. While his human self is played by Danny DeVito. The other M&M's usually make fun of him because he is the shortest. Red can be described as the "main character" of the M&M's.

Yellow is the spokescandy for Peanut M&Ms. He is one of the two "nut" M&Ms, the other being the Almond M&M, Blue. Yellow is the happy go-lucky one of the M&MS. He always tries to see the best in things, and is almost never sad. He is Red's best friend and is always by his side in the commercials. Red usually uses Yellow to make him do things he doesn't want to do, taking advantage of Yellow being gullible, but in the end they are best friends. He was originally voiced by John Goodman, who also voiced Sulley in Monsters Inc., and portrayed Ocious P. Potter in The Borrowers, and is currently voiced by J.K. Simmons, who also voiced J. Jonah Jameson in Sam Raimi's Spider-Man trilogy, Cave Johnson in the video game Portal 2, Tenzin in The Legend of Korra, Stanford Pines in Gravity Falls, Kai in Kung Fu Panda 3, and Mayor Lionheart in Zootopia.