Patients you'll see
Heme: mostly sickle cell, ITP, pulmonary emboli
Onc: B cell ALL, T cell ALL, teratoid tumors, medulloblastoma, neuroblastoma, lymphoma, febrile neutropenia
Sickle Cell Crisis Basics:
know pain scale, are the meds relieving the pain?
The patient can go home when pain is adequately controlled with the inpatient medication equivalent to the home meds.
Assess ability to do ADLs.
Know the baseline Hb, and absolute retic count.
Know the conversions from oral morphine to IV (1:3) and how to convert to other opioids.
IV morphine should start working in 20min.
Side effect of opioids: constipation. Generally need Senna and Miralax.
When someone is on a PCA pump, continuous naloxone can be used for itching.
Encourage deep breathing/incentive spirometry and getting out of bed.
Chemotherapy basics:
Know the cycle, week, day of chemotherapy and what drugs they are receiving
Steroids (ie dexamethasone) count as chemo and are one of the first things started
Almost everyone gets an LP and bone marrow biopsy/aspirate for new diagnosis
Also: Intrathecal chemotherapy means it is administered into spinal fluids ie during an LP
Everyone has a roadmap based on their diagnosis and severity of disease. Road maps outline their chemotherapy meds and schedule. They're usually at the nursing station in the front of the unit. Other times you need to ask Julie the NP
Pharmacy orders the chemotherapy: ask Desiree (pharmacist) or Julie (NP) about schedule for meds if needed
Never EVER adjust chemotherapy meds on your own. Those should never be managed by just residents!
Always keep the fellows/attendings in the loop. To be honest, they never want to be kept out of the loop!
Bleomycin: fever, weight loss, vomiting, and rash, anaphylaxis, pulmonary fibrosis
Cisplatin: bone marrow suppression, hearing problems, kidney problems
Cyclophosphamide: leukopenia, loss of appetite, vomiting, alopecia, and hemorrhagic cystitis (check urine for hematuria)
Dacarbazine: loss of appetite, vomiting, low white blood cell count, and low platelets.
Dexamethasone (steroids): craving for salty foods, cushingoid facies, bone mass loss, GI upset
Docetaxel: alopecia, low blood cell counts, numbness, shortness of breath, vomiting, and muscle pains.
Doxorubicin: Pts need an ECHO. Hair loss, bone marrow suppression, vomiting, rash, stomatitis
Methotrexate: mucositis, bone marriow suppression
Vinblastine: SIADH, change in sensation, constipation, weakness, loss of appetite, and headaches, low blood cell counts and shortness of breath
Vincristine: SIADH, peripheral neuropathy, hair loss, constipation, difficulty walking, and headaches.