Our Work

Please see the full publication list:  Google Scholar Profile

Alam, F., Blackburn, S., Davis, J., Massar, K., Correia, J., Tsai, H.-J., Blair, J and Hall, R.A. (2023). Pseudomonas aeruginosa increases the susceptibility of Candida albicans to amphotericin B in dual species biofilms. Journal Antimicrobial Chemotherapy, Jul 31:dkad228 

Jones, C., Zhang, ZJ., and Tsai, H-J. (2023). Quantifying the mechanical properties of yeast Candida albicans using atomic force microscopy-based force spectroscopy. Methods Mol Biol  2667, 1-13.  

Credle, J.J., Gunn, J., Sangkhapreecha, P., Monaco, D.R., Zheng, X.A., Tsai, H.-J., Wilbon, A., et al. (2022). Unbiased discovery of autoantibodies associated with severe COVID-19 via genome-scale self-assembled DNA-barcoded protein libraries. Nature Biomedical Engineering 6, 992–1003.

Kumwenda, P., Cottier, F., Keevan, B., Gallagher, H., Tsai, H.-J., and Hall, R.A. (2020). Oestrogen promotes innate immune evasion of Candida albicans through inactivation of the alternative complement system. Cell Report 38, 110183.

Tsai H-J, Nelliat AR. 2019. A Double-Edged Sword: Aneuploidy is a Prevalent Strategy in Fungal Adaptation. Gene 10: 787. https://doi.org/10.3390/genes10100787

Tsai H-J, Nelliat AR, Choudhury MI, Kucharavy A, Bradford WD, Cook ME, Kim J, Mair DB, Sun SX, Schatz MC, Li R. 2019. Hypo-osmotic-like stress underlies general cellular defects of aneuploidy. Nature 570:117–121. https://doi.org/10.1038/s41586-019-1187-2

Bijlani S, Thevandavakkam MA, Tsai H-J, Berman J. 2019. Autonomously Replicating Linear Plasmids That Facilitate the Analysis of Replication Origin Function in Candida albicans. mSphere 4:e00103-19. https://doi.org/10.1128/mSphere.00103-19

Zhu J, Tsai H-J, Gordon MR, Li R. 2018. Cellular Stress Associated with Aneuploidy. Dev Cell 44:420–431. DOI: 10.1016/j.devcel.2018.02.002

Mulla WA, Seidel CW, Zhu J, Tsai H-J, Smith SE, Singh P, Bradford WD, McCroskey S, Nelliat AR, Conkright J, Peak A, Malanowski KE, Perera AG, Li R. 2017. Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast. Elife 6:e27991 DOI: 10.7554/eLife.27991

Chen G, Mulla WA, Kucharavy A, Tsai H-J, Rubinstein B, Conkright J, McCroskey S, Bradford WD, Weems L, Haug JS, Seidel CW, Berman J, Li R. 2015. Targeting the adaptability of heterogeneous aneuploids. Cell 160:771–784. DOI: 10.1016/j.cell.2015.01.026

Tsai H-J, Baller JA, Liachko I, Koren A, Burrack LS, Hickman MA, Thevandavakkam MA, Rusche LN, Berman J. 2014. Origin replication complex binding, nucleosome depletion patterns, and a primary sequence motif can predict origins of replication in a genome with epigenetic centromeres. MBio 5:e01703–14. DOI: https://doi.org/10.1128/mBio.01703-14

Furniss KL, Tsai H-J, Byl JAW, Lane AB, Vas AC, Hsu W-S, Osheroff N, Clarke DJ. 2013. Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation. PLoS Genet 9:e1003832.

Koren A, Tsai H-J, Tirosh I, Burrack LS, Barkai N, Berman J. 2010. Epigenetically-inherited centromere and neocentromere DNA replicates earliest in S-phase. PLoS Genet 6:e1001068.

Tsai H-J, Huang W-H, Li T-K, Tsai Y-L, Wu K-J, Tseng S-F, Teng S-C. 2006. Involvement of topoisomerase III in telomere-telomere recombination. J Biol Chem 281:13717–13723.

Wen W-Y, Tsai H-J, Lin C-C, Tseng S-F, Wong C-W, Teng S-C. 2006. Telomere configuration influences the choice of telomere maintenance pathways. Biochem Biophys Res Commun 343:459–466.