TomoDenoise

Fast software for 3D denoising in Electron Tomography,

CryoET and Volume Electron Microscopy (vEM).

Contact: jjfernandez.software _at_ gmail.com

TomoDenoise contains software programs for 3D noise filtering of tomograms in Electron Tomography, CryoET and volume Electron Microscopy. The programs are fast, memory-efficient and also user-friendly in terms of parameter tuning. The package contains programs for linear, non-linear and anisotropic denoising that can be downloaded individually or the whole package TomoDenoise at once.

Individual programs

Linear Denoising

TomoGauss - Denoising based on Gaussian Filtering.

Non-Linear Denoising

TomoBFlow - Denoising based on Beltrami Flow.

Anisotropic Denoising

TomoAND/TomoEED - Denoising with Anisotropic Non-Linear Diffusion (AND).
TomoNLM - Denoising with Non-Local Means (coming soon).
FlowDenoising - Denoising with Structure-preserving Gaussian filtering.

Download the TomoDenoise software

Current version: March 2025

Available material:

Binaries for x86-based platforms under Linux and OSX (64 bits).