Tsung-Hsi Tu, Ching-Jung Chen, Li-Yu Fay, Zhi-Hu Lin, Wang-Yu Hsu, Chien-Hui Hung, Meng-Jen Lee, May-Jywan Tsai, Ai-Jung Tseng, Jau‐Ching Wu, Wen-Cheng Huang, Tung-Yi Lin*. Ganoderma microsporum–derived fungal immunomodulatory protein (GMI) promotes functional recovery after spinal cord injury by modulating inflammation and enhancing regeneration. Experimental Neurology. 2026. 396:115536. (SCI, IF: 4.2, Rank: 23.6%) Corresponding author

Wei-Jyun Hua, Li-Chen Huang, Zhi-Hu Lin, Yi-Ru Ciou, Kai-Fan Lin, Li-Lan Liao, Wei-Hung Hsu, Tung-Yi Lin*. Suppression of tumor growth by GMI, an edible fungal immunomodulatory protein, is associated with targeting GSK3β‑mediated proteasomal degradation of PD‑L1. International Journal of Molecular Medicine. 2025. 56(6): 1-14. (SCI, IF: 5.8, Rank: 19.7%)

Zhi-Hu Lin, Hsin Yeh, Sang-Nguyen-Cao Phan, Li-Lan Liao, Chien-Chang Chen, Wei-Hung Hsu, Chung-Hua Hsu and Tung-Yi Lin*. Jing Guan Fang, an herbal formula, as an immunomodulator: opposing effects on basal and lipopolysaccharide-induced inflammation of macrophage via JAK/STAT3 and MAPK pathways. Frontiers in Pharmacology. 2025. 16:1618488. (SCI, IF: 4.8, Rank: 14.3%)

 Di Ngoc Kha Vo, Ha Phan Thanh Ho, Li-Syuan Wu, Yi-Yun Chen, Hang Thi Viet Trinh, Tung-Yi Lin, Yat-Yuen Lim, Keng-Chang Tsai, Ming-Han Tsai*. Broad-spectrum antiviral activity of Ganoderma microsporum immunomodulatory protein: Targeting glycoprotein gB to inhibit EBV and HSV-1 infections via viral fusion blockage. International Journal of Biological Macromolecules. 2025. 307(part3): 142179. (SCI, IF: 7.7, Rank: 6.4%)

 Zhi-Hua Lin, Sang-Nguyen-Caoa Phan, Diem-Ngoc-Honge Tran, Mei-Kuanga Lu, Tung-Yi Lin*. Anti-inflammatory and anti-cancer effects of polysaccharides from Antrodia cinnamomea: A review. Journal of the Chinese Medical Association. 2025 Jan 1;88(1):1-11. (SCI, IF: 2.4, Rank: 23.3%) Corresponding author

 Zhi-Hu Lin, Hung-Chih Lo, Chia-Chuan Chang, Mei-Kuang Lu*, Ai-Jung Tseng, Chi-Hsein Chao, Chi-Hong Chao, Tung-Yi Lin*. Sulfated polysaccharide from Antrodia cinnamomea mycelium cultured with zinc sulfate stimulates M1 polarization of macrophages through AKT/mTOR pathways. International Journal of Biological Macromolecules. 2024. 279: 135548. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Hung-Chih Lo, Tzu-En Lin, Che-Yu Lin, Wei-Hao Wang, Yu-Chen Chen, Pei-Hsien Tsai, Jung-Chen Su, Mei-Kuang Lu, Wei-Hung Hsu, Tung-Yi Lin*. Targeting TGFβ receptor-mediated snail and twist: WSG, a polysaccharide from Ganoderma lucidum, and it-based dissolvable microneedle patch suppress melanoma cells. Carbohydrate Polymers. 2024. 341:122298. (SCI, IF: 10.7, Rank: 1.7%) Corresponding author

 Chung-Ting Kao, Fan-Wei Yang, Meng-Chen Wu, Tzu-Huan Hung, Chen-Wei Hu, Chiu-Hua Chen, Pin-Chien Liou, Te-Lun Mai, Chia-Chih Chang, Tung-Yi Lin, Ying-Lan Chen*, Ying-Chung Jimmy Lin*, Jung-Chen Su*. Systematic synthesis and identification of monolignol pathway metabolites. New Phytologist. 2024. (SCI, IF: 8.3, Rank: 4.2%)

 Wei-Jyun Hua, Wei-Lun Hwang, Hsin Yeh, Zhi-Hu Lin, Wei-Hung Hsu, Tung-Yi Lin*. Ganoderma microsporum immunomodulatory protein combined with KRASG12C inhibitor impedes intracellular AKT/ERK network to suppress lung cancer cells with KRAS mutation. International Journal of Biological Macromolecules. 2024. 259:129291. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Hung-Chih Lo, Wei-Jyun Hua, Hsin Yeh, Zhi-Hu Lin, Li-Chen Huang, Yi-Ru Ciou, Runcheng Ruan, Kai-Fan Lin, Ai-Jung Tseng, Alexander T.H. Wu, Wei-Hung Hsu, Chi-Hong Chao, Tung-Yi Lin*. GMI, a Ganoderma microsporum protein, abolishes focal adhesion network to reduce cell migration and metastasis of lung cancer. Life Sciences. 2023. 335: 122255. (SCI, IF:5.2, Rank: 11.3%) Corresponding author

 Wei-Jyun Hua, Hsin Yeh, Zhi-Hu Lin, Ai-Jung Tseng, Li-Chen Huang, Wei-Lun Qiu, Tsung-Hsi Tu, Ding-Han Wang, Wei-Hung Hsu, Wei-Lun Hwang, Tung-Yi Lin*. Ganoderma microsporum immunomodulatory protein as an extracellular epidermal growth factor receptor (EGFR) degrader for suppressing EGFR-positive lung cancer cells. Cancer Letters. 2023. 578: 216458. (SCI, IF: 9.1, Rank: 10.2%) Corresponding author

 Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Ling Yang, Tung-Yi Lin, Muh-Hwa Yang, Tung-Hu Tsai*. Transporter modulation of molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-brain barrier in a rat. Communications medicine. 2023. 3: 150. (SCI, IF: 5.4, Rank: 19.0%)

 Chueh-Tan Chen, Chian-Feng Chen, Tung-Yi Lin, Wei-Jyun Hua, Kate Hua, Ching-Yao Tsai*, Chung-Hua Hsu*. Traditional Chinese medicine Kuan-Sin-Yin decoction inhibits cell mobility via downregulation of CCL2, CEACAM1 and PIK3R3 in hepatocellular carcinoma cells. Journal of Ethnopharmacology. 2023. 317:114636. (SCI, IF: 4.8, Rank: 9.3%) Third author 

 Wei-Lun Qiu, Hung-Chih Lo, Mei-Kuang Lu, Tung-Yi Lin*. Significance of culture period on the physiochemistry and anti-cancer potentials of polysaccharides from mycelia of Ganoderma lucidum. International Journal of Biological Macromolecules. 2023. 242:125181. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Tung-Yi Lin, Muh-Hwa Yang, Jeffrey W. Dalley, Tung-Hu Tsai*. Transfer and biotransformation of the COVID-19 prodrug molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-placenta barrier. eBioMedicine. 2023. 95: 104748. (SCI, IF: 9.7, Rank: 6.3%)

 Yong-Hong Yang, Che-Sheng Wen, Yung-Ling Kuo, Su-Ling Fu, Tung-Yi Lin, Chao-Ming Chen, Po-Kuei Wu, Wei-Ming Chen, Jir-You Wang. GuiLu-ErXian Glue extract promotes mesenchymal stem cells (MSC)-Induced chondrogenesis via exosomes releases and delays aging in the MSC senescence process. Journal of Ethnopharmacology. 2023. 317: 116784. (SCI, IF: 4.8, Rank: 9.3%)

 Chun-Hao Chang, Wen-Ya Peng, Wan-Hsin Lee, Tung-Yi Lin, Muh-Hwa Yang, Jeffrey W. Dalley, Tung-Hu Tsai*. Biotransformation and brain distribution of the anti-COVID-19 drug molnupiravir and herb-drug pharmacokinetic interactions between the herbal extract Scutellaria formula-NRICM101. Journal of Pharmaceutical and Biomedical Analysis. 2023. 234:115499. (SCI, IF: 3.1, Rank: 34.9%)

 Zhi-Hu Lin, Hsin Yeh, Hung-Chih Lo, Wei-Jyun Hua, Ming-Yang Ni, Li-Kai Wang, Ting-Ting Chang, Muh-Hwa Yang, Tung-Yi Lin*. GMI, a fungal immunomodulatory protein, ameliorates SARS-CoV-2 envelope protein-induced inflammation in macrophages via inhibition of MAPK pathway. International Journal of Biological Macromolecules. 2023. 241: 124648. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Zhi-Hu Lin, Mei-Kuang Lu, Hung-Chih Lo, Chia-Chuan Chang, Ai-Jung Tseng, Chi-Hsein Chao, Tung-Yi Lin*. ZnF3, a sulfated polysaccharide from Antrodia cinnamomea, inhibits lung cancer cells via induction of apoptosis and activation of M1-like macrophage-induced cell death. International Journal of Biological Macromolecules. 2023. 238:124144. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Tung-Yi Lin*, Hung-Chih Lo, Wei-Lun Qiu, Chi-Hsein Chao, Mei-Kuang Lu, and Hsien-Yeh Hsu. Biochemical characterization and anti-cancer activity of tangential flow filtration system assisted purification of fucoglucan from Laminaria japonica. International Journal of Biological Macromolecules. 2023. 227:1-9. (SCI, IF: 7.7, Rank: 6.4%) First & Corresponding author

 Ai-Jung Tseng, Tsung-Hsi Tu, Wei-Jyun Hua, Hsin Yeh, Ching-Jung Chen, Zhi-Hu Lin, Wei-Hung Hsu, Ying-Lan Chen, Chuan-Chih Hsu, Tung-Yi Lin*. GMI, Ganoderma microsporum protein, suppresses cell mobility and increases temozolomide sensitivity through induction of Slug degradation in glioblastoma multiforme cells. International Journal of Biological Macromolecules. 2022. 219:940-948. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Yi-Hong Lin, Chih-Ning Tsai, Po-Feng Chen, Yen-Tzu Lin, Sorour Darvishi, Hubert H. Girault, Tung-Yi Lin, Mei-Yi Liao, and Tzu-En Lin*. AI-Assisted Fusion of Scanning Electrochemical Microscopy Images Using Novel Soft Probe. ACS Measurement Science Au. 2022. 6:576-583. (SCI, IF: 4.6, Rank: 19.8%)

 Tzu-En Lin*, Ming-Chun Chien, Po-Feng Chen, Pei-Wen Yang, Huai-En Chang, Ding-Han Wang, Tung-Yi Lin, and Yung-Jung Hsu. A Sensor-Integrated Face Mask Using Au@SnO2 Nanoparticle Modified Fibers and Augmented Reality Technology. ACS Omega. 2022. 7:42233-42241. (SCI, IF: 3.7, Rank: 36.5%)

 Leonel Pereira, Chia-Chuan Chang, Jianxun Ding, Tung-Yi Lin and Zhong Liu. The polysaccharides from marine organisms and fungi: Biological functions and molecular mechanisms. Frontiers in Pharmacology. 2022. 13:1085346. (SCI, IF: 4.4, Rank: 18.4%)

 Ha Phan Thanh Ho, Di Ngoc KhaVo, Tung-Yi Lin, Jo-Ning Hung, Ya-Hui Chiu, Ming-Han Tsai*. Ganoderma microsporum immunomodulatory protein acts as a multifunctional broad-spectrum antiviral against SARS-CoV-2 by interfering virus binding to the host cells and spike-mediated cell fusion. Biomedicine & Pharmacotherapy. 2022. 155:113766. (SCI, IF: 6.9, Rank: 4.2%) Third author

 Hsin Yeh, Di Ngoc Kha Vo, Zhi-Hu Lin, Ha Phan Thanh Ho, Wei-Jyun Hua, Wei-Lun Qiu, Ming-Han Tsai, Tung-Yi Lin*. GMI, a protein from Ganoderma microsporum, induces ACE2 degradation to alleviate infection of SARS-CoV-2 Spike-pseudotyped virus. Phytomedicine. 2022. 103: 154215. (SCI, IF: 6.7, Rank: 4.7%) Corresponding author

 Yueh-Hsin Ping, Hsin Yeh, Li-Wei Chu, Zhi-Hu Lin, Yin-Chieh Hsu, Lie-Chwen Lin, Chung-Hua Hsu, Shu-Ling Fu, Tung-Yi Lin*. The Traditional Chinese Medicine Formula Jing Guan Fang for preventing SARS-CoV-2 infection: from clinical observation to basic research. Frontiers in Pharmacology. 2022. 13:744439. (SCI, IF: 4.4, Rank: 18.4%) Corresponding author

 Yun-Tsung Chen, Yao-Yi Hsieh, Jen-Yu Ho, Chien Chang Ho, Tung-Yi Lin* and Jung-Charng Lin. Running interval training combined with blood flow restriction increases maximal running performance and muscular fitness in male runners. Scientific reports. 2022. 12:9922. (SCI, IF: 3.8, Rank: 18.7%) Corresponding author

 Kai-Wei Chang, Tung-Yi Lin, Shu-Ling Fu, Yueh-Hsin Ping, Fen-Pey Chen, Yen-Ying Kun*. A Houttuynia Cordata-based Chinese herbal formula improved symptoms of allergic rhinitis during COVID-19 pandemic. Journal of the Chinese Medical Association. 2022. 85(6):717-722. (SCI, IF: 1.9, Rank: 32.0%) Second author 

 Yun-Tsung Chen, Yao-Yi Hsieh, Jen-Yu Ho, Tung-Yi Lin* and Jung-Charng Lin. Two weeks of detraining reduces cardiopulmonary function and muscular fitness in endurance athletes. European journal of sport science. 2022. 22(3):399-406. (SCI, IF: 2.4, Rank: 28.3%) Corresponding author

 Yun-Tsung Chen, Yao-Yi Hsieh, Jen-Yu Ho, Tung-Yi Lin, and Jung-Charng Lin. Running training combined with blood flow restriction increases cardiopulmonary function and muscle strength in endurance athletes. Journal of strength and conditioning research. 2022. 36(5):1228-1237. (SCI, IF: 2.5, Rank: 26.0%)

 Zhi-Hu Lin, Jinsong Hu, Huagang Shi, Chia-Ching Liaw, Wei-Lun Qiu, Wei-Hung Hsu, Tung-Yi Lin*. Water extract of medicinal ink (WEMI) attenuates lipopolysaccharide-induced NO production of Raw264.7 cells via downregulation JAK2/STAT3-mediated iNOS expression. Journal of Ethnopharmacology. 2022. 282:114636. (SCI, IF: 4.8, Rank: 9.3%) Corresponding author 

 Wei-Lun Qiu, Wei-Hung Hsu, Shu-Ming Tsao, Ai-Jung Tseng, Zhi-Hu Lin, Wei-Jyun Hua, Hsin Yeh, Tzu-En Lin, Chien-Chang Chen, Li-Sheng Chen, Tung-Yi Lin*. WSG, a glucose-rich polysaccharide from Ganoderma lucidum, combined with cisplatin potentiates inhibition of lung cancer in vitro and in vivo. Polymers. 2021. 13(24):4353. (SCI, IF: 4.7, Rank: 19.1%) Corresponding author 

 Wei-Hung Hsu, Wei-Jyun Hua, Wei-Lun Qiu, Ai-Jung Tseng, Hsin-Chung Cheng, Tung-Yi Lin*. WSG, a glucose-enriched polysaccharide from Ganoderma lucidum, suppresses tongue cancer cells via inhibition of EGFR-mediated signaling and potentiates cisplatin-induced apoptosis. International Journal of Biological Macromolecules. 2021. 193:1201-1208. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Tung-Yi Lin*, Wei-Jyun Hua, Hsin Yeh, Ai-Jung Tseng. Functional proteomic analysis reveals that fungal immunomodulatory protein reduced expressions of heat shock proteins correlates to apoptosis in lung cancer cells. Phytomedicine. 2021. 80:153384. (SCI, IF: 6.7, Rank: 4.7%) First & Corresponding author

 Wei-Shan Hsu, Anant Preet, Tung-Yi Lin and Tzu-En Lin*. Miniaturized Salinity Gradient Energy Harvesting Devices. Molecules. 2021. 26(18): 5469. (SCI, IF: 4.2, Rank: 28.1%) Third author

 Wei-Hung Hsu, Wei-Lun Qiu, Shu-Ming Tsao, Ai-Jung Tseng, Mei-Kuang Lu, Wei-Jyun Hua, Hsin-Chung Cheng, Hsien-Yeh Hsu, Tung-Yi Lin*. Effects of WSG, a polysaccharide from Ganoderma lucidum, on suppressing cell growth and mobility of lung cancer. International Journal of Biological Macromolecules. 2020. 165:1604-1613. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author

 Tung-Yi Lin*, Mei-Kuang Lu, Ai-Jung Tseng, Chi-Hsein Chao. Effects of sterol-type elicitors on biochemical characterization of polysaccharides from Antrodia cinnamomea. International Journal of Biological Macromolecules. 2020. 162:1476-1483. (SCI, IF: 7.7, Rank: 6.4%) First & Corresponding author

 Tung-Yi Lin, Mei-Kuang Lu, Chia-Chuan Chang*. Structural identification of a fucose-containing 1,3-β-mannoglucan from Poria cocos and its anti-lung cancer CL1-5 cells migration via inhibition of TGFβR-mediated signaling. International Journal of Biological Macromolecules. 2020. 157:311-318. (SCI, IF: 7.7, Rank: 6.4%) First author

 Wei-Lun Qiu, Ai-Jung Tseng, Hsien-Yeh Hsu, Wei-Hung Hsu, Zhi-Hu Lin, Wei-Jyun Hua, Tung-Yi Lin*. Fucoidan increased the sensitivity to gefitinib in lung cancer cells correlates with reduction of TGFβ-mediated Slug expression. International Journal of Biological Macromolecules. 2020. 153:796-805. (SCI, IF: 7.7, Rank: 6.4%) Corresponding author