2024

• C. DiNardo, D. Verma, N. Baran, T. D. Bhagat, A. Lodi, K. Saxena, T. Cai, X. Su, A. Skwarska, V. A. Guerra, V. M Kuruvilla, S. Konoplev, S. Gordon-Mitchell, K. Pradhan, S. Aluri, G. L. Hackman, M. Collins, S. R. Sweeney, J. Busquets, A. S. Rathore, Q. Deng, M. Green, S. Grant, G. Hatzivassiliou, S. Demo, S. Whiting, M. Gelman, G. S. Chaudhary, S. Sahu, M. Spodek, V. Thiruvanthan, B. Will, U. Steidl, D. Tipett, J. Burger, G. Borthakur, E. Jabbour, N. Pemmaraju, T. Kadia, S. Kornblau, N. G. Daver, K. Naqvi, N. Short, G. Garcia-Manero, S. Tiziani*, A. Verma*, M. Konopleva* “Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses” Nature Cancer PMID: 36865338 (*equal contribution corresponding authors, in press, 2024)

• M.-J. Lu, J. Busquets, V. Impedovo, C. N. Wilson, H.-R. Chan, Y.-T. Chang, W. Matsui, S. Tiziani, X. A. Cambronne “SLC25A51 Decouples the Mitochondrial NAD+/NADH Ratio to control proliferation of AML cells” Cell Metabolism, DOI:https://doi.org/10.1016/j.cmet.2024.01.013 (in press, 2024)

• M. A. Liss, F. Durson, G. L. Hackman, M. I. Gadallah, A. Saha, Chelsea A. Friedman, A. S. Rathore, P. Chandra, J. R. White, S. Tiziani, and J. DiGiovanni “Phase 1 Clinical Trial Evaluating Safety, Bioavailability, and Gut Microbiome with a Combination of Curcumin and Ursolic Acid in Lipid Enhanced Capsules” Journal of Traditional and Complementary Medicine (in press, 2024)

• S. M Stanford, T. P. Nguyen, J. Chang, G. L. Hackman, E. Santelli, C. M. Sanders, M. Katiki, E. Dondossola, M. A. Diaz, P. Watson, B. Sankaran, C. Paindelli, V. Parietti, A. G. Mikos, A. Elliott, A. Lodi, A. Bagrodia, C. Sawyers, R. McKay, R. Murali, S. Tiziani, A. Kettenbach, N. Bottini “Low molecular weight protein tyrosine phosphatase protects prostate cancer from oxidative stress through a novel role in glutathione production” Science Advances, 10(5), eadg7887 (2024)

• C. A. Friedman,  A. Saha, G. L. Hackman, X. Lu,  A. Lodi, S. Tiziani, and J. DiGiovanni “Novel Two-Tiered Screening Approach Identifies Synergistic Combinations of Natural Compounds for Cancer Prevention and Treatment” Molecular Carcinogenesis, 1-12 (2024)

• K. Hurrish, Y. Su, S. Patel, C. Ramage, J. Zhao, B. R. Temby, J. Carter, H. Edwards, S. Buck, S. Wiley, M. Hüttemann, L. Polin, J. Kushner, S. Dzinic, K. White, X. Bao, J. Li, J. Yang, J. Boerner, Z. Hou, G. Al-Atrash, S. Konoplev, J. Busquets, S. Tiziani, L. Matherly, J. Taub, M. Konopleva, Y. Ge, N. Baran “Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and purine biosynthesis” Biochemical Pharmacology, 220, 115981 (2024)

• F. De Leonardis, A. Ahmed, A Vozza, L. Capobianco, C. L. Riley, S. Nicole Barile, D. Di Molfetta, S. Tiziani, J. DiGiovanni, L. Palmieri, V. Dolce, and G. Fiermonte “Functional characterization of human mitochondrial uncoupling protein 3” FEBS Letters, 598(3), 338-346 (2024)

2023

• C. S Wilder, J. Chiou, A. Battenhouse, A. Saha, Z. Chen, E. Kim, M. I Gadallah, S. Tiziani, G. Georgiou, E. Stone, J. DiGiovanni “Enzymatic depletion of L-Met using an engineered human enzyme as a novel therapeutic strategy for melanoma” Molecular Carcinogenesis, 62, 1531-1545 (2023)

• T. A. Yap, N. Daver, M. Mahendra, J.  Zhang, C. Kamiya-Matsuoka, F. Meric-Bernstam, H. M Kantarjian, F. Ravandi, M. E. Collins, M. E. Di Francesco, E. E. Dumbrava, S. Fu, S. Gao, J. P. Gay, S. Gera, J. Han, D. S. Hong, E. J. Jabbour. Z. Ju, D. D Karp, A. Lodi, Jennifer, R. Molina, N. Baran, A. Naing, M. Ohanian, S. Pant, N. Pemmaraju, P. Bose, S. A. Piha-Paul, J. Rodon, C. Salguero, K. Sasaki, An. K. Singh, V. Subbiah, A. M. Tsimberidou, Q. A. Xu, M. Yilmaz, Q. Zhang, Y. Li, C. A Bristow, M. B. Bhattacharjee, S. Tiziani, T. P. Heffernan, C. P. Vellano, P. Jones, C. J. Heijnen, A. Kavelaars, J. R. Marszalek, M. Konopleva "Complex I Inhibitor of Oxidative Phosphorylation in Advanced Solid Tumors and Acute Myeloid Leukemia: Phase I Trials" Nature Medicine, 29, 115-126 (2023)

• G. Lauria, R. Curcio, P. Lunetti, S. Tiziani, V. Coppola, V. Dolce, G. Fiermonte, A. Ahmed “Role of mitochondrial transporters on metabolic rewiring of pancreatic adenocarcinoma: a comprehensive review” Cancers, 15(2), 411 (2023)

• X. Hua, R. Marick, Y. Li, S. R. Pentaparthi, D. J. McGrail, R. Zou, L. Guo, A. Shrawat, K. M. Cirillo, Q. Li, A. V. Bhat, M. Xu, D. Qi, A. Singh, F. McGrath, S. B. Andrews, K. L. Aung, J. Das, DY. Zhou, A. Lodi, G. B. Mills, S. G. Eckhardt, M. L. Mendillo, S. Tiziani, E, Wu, J. H. Huang, N. Sahni, S. S. Yi “mGI-map: Landscape of microRNA regulatory network architecture and functional rerouting in cancer” Cancer Research, 83 (1), 59-81 (2023)

• A. Kosti, J. Chiou, G. Guardia, X. Lei, H. Balinda, T. Landry, X. Lu, M. Qiao, A. Gilbert, A. Brenner, P. F. Galante, S. Tiziani, L. O F Penalva “ELF4 is a critical component of a miRNA-transcription factor network and regulates glioblastoma receptor signaling and lipid dynamics” Neuro-Oncology,  14, 25(3), 459-470 (2023)

2022

• A. Lodi, R. Pandey, J. Chiou, A. Bhattacharya, S. Huang, X. Pan, B. Burgman, S. Yi, S. Tiziani and A. J Brenner “Circulating metabolites associated with tumor hypoxia and early response to treatment in Bevacizumab-refractory glioblastoma after combined Bevacizumab and Evofosfamide” Frontiers in Oncology, https://doi.org/10.3389/fonc.2022.900082 (2022)

• B. McClellan, P. Gries, B. Harlow, S. Tiziani, C. Jolly, L. DeGraffenried “An IGF-1R-mTORC1-SRPK2 Signaling Axis Contributes to FASN Regulation in Breast Cancer” BMC Cancer, 22(1):976 (2022)

• X. Lu, G. L. Hackman, A. Saha, A. Rathore, M. Collins, S. S. Yi, F. Matsuda, J. DiGiovanni, A. Lodi, S. Tiziani “Metabolomics-based phenotypic screens for evaluation of drug synergy via direct-infusion mass spectrometry” iScience, 25 (5), 104221 (2022)

Highlight: DDN, Exploring Drug Discovery and Development: “From Flamingos to Better Cancer Treatments “

• H. Wang, X. He, H. Dong, F. Huang, V. Huang, Min Li, W. Chen, X. Lu, K. V. Pathak, Z. Li, L. Zhang, J. Sun, Y. Zhu, Y. Wu, L. Zhang, L. Xuan, T. Nguyen, L. Yang, L. Feng, D. Gordon, J. Zhang, P. Pirrotte, D. Chen, A. Salhotra, Y.-H. Kuo, D. Horne, G. Marcucci, D. Sykes, S. Tiziani, H. Jin, X. Wang, L. Li “Disruption of dNTPs Homeostasis by Ribonucleotide Reductase Hyperactivation Overcomes AML Differentiation Blockade” Blood, The Journal of the American Society of Hematology, 139(26), 3752-3770 (2022)

• Z. Hou, X. Lu, S. Tiziani, F. Lee “Nutritional programming by maternal diet alters offspring lipid metabolism in a marine teleost" Fish Physiology and Biochemistry, 11, 1 (2022)

• N. Baran, A. Lodi, Y. Dhungana, S. Sweeney, R. Pandey,  S. Herbrich, F. W. Hof, A. Skwarska,  M. Kaplan, V. M. Kuruvilla, A. Cavazos, H. Ma, M. Warmoes, D. T. Veiga, K. Furudate, S. Rojas-Sutterin, A. Haman, Y Gareau, A. Marinier,  K. Harutyunyan, M. Daher, L. Melo Garcia, S. Piya, V. Ruvolo, W. Yang, S. Saravanan Shanmugavelandy, N. Feng, J. Gay, D. Du, J. J. Yang, K. Tomczak, M. Kaminski,  E. Davis,  D. Herranz, A. Ferrando, E. J. Jabbour, M. E. Di Francesco, D. T. Teachey, T. M. Horton, K. Rezvani, G. Sauvageau, S. Kornblau, M. G. Iurascu, K. Takahashi, M. Andreeff, J. R. Marszalek, P. L. Lorenzi, J. Yu, S. Tiziani, T. Hoang, M. Konopleva “Inhibition of Mitochondrial complex I reverses the NOTCH1-driven metabolic reprogramming in T-ALL” Nature Communications, 13 (1), 2801 (2022)

• K. A. Lewis, N. Osier, R. Carrasco, J. Chiou, P. Carter, A. Garcia, E. Flowers, E. D. Gennatas, C. Nguyen, A. Rana, S. A. Brown, S. Tiziani "Serine, N-acetylaspartate Differentiate Adolescents with Juvenile Idiopathic Arthritis Compared with Healthy Controls: A Metabolomics Cross-Sectional Study" Pediatric Rheumatology, 20, 12 (2022)

• Q. Zhang, B. Riley-Gillis, L. Han, Y. Jia, A. Lodi, H. Zhang, S. Ganesan, R. Pan, S. N. Konoplev, S. R. Sweeney, J. A. Ryan, Y. Jitkova, K. Dunner Jr., S. E. Grosskurth, P. Vijay, S. Ghosh, C. Lu, W. Ma, S. Kurtz, V. R. Ruvolo, H. Ma, C. Weng, C. L. Ramage, N. Baran, C. Shi, T. Cai, R. E. Davis, V. L. Battula, Y. Mi, J. Wang, C. D DiNardo, M. Andreeff, J. W. Tyner, A. Schimmer, A. Letai, R. A. Padua, C. E. Bueso-Ramos, S. Tiziani, J. Leverson, R. Popovic, M. Konopleva “Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia” Signal Transduction and Targeted Therapy, 7, 51 (2022)

• R. Gorgoglione, V. Impedovo, C. L Riley, D. Fratantonio, S. Tiziani, L. Palmieri, V. Dolce, G. Fiermonte “Glutamine-derived aspartate biosynthesis in cancer cells: role of mitochondrial transporters and new therapeutic perspectives” Cancers, 14, 245 (2022)

2021

• P. Gries, A. Rathore, X. Lu, J. Chiou, Y. B. Huynh, A. Lodi, S. Tiziani “Automated Trimethyl Sulfonium Hydroxide Derivatization Method for High-Throughput Fatty Acid Profiling by Gas Chromatography-Mass Spectrometry”, Molecules, 26(20), 6246 (2021)

• K. A. Lewis, S. Brooks, R. Carrasco, P. Carter, A. Garcia, J. Chiou, C. Nguyen, A. Rana, S. A. Brown, S. Tiziani, N. Osier “Best Practices for Recruitment of Older Adolescents for Biobanking and Precision Health Research: A Retrospective Analysis Comparing Juvenile Idiopathic Arthritis Cases with Healthy Controls” Pediatric Rheumatology, 19, 169. PMID: 34863185 (2021)

• X. Lu, L. Han, J. Busquets, M. Collins, A. Lodi, J. R Marszalek, M. Konopleva, S. Tiziani “The combined treatment with the FLT3-inhibitor AC220 and the complex I inhibitor IACS-010759 synergistically depletes wt- and FLT3-mutated acute myeloid leukemia cells”, Frontiers in Oncology, 3158 doi: 10.3389/fonc.2021.686765 (2021)

• M. Z. Thomas, X. Lu, Z. Talebi, J. Y. Jeon, D. Buelow, A. Gibson, M. E. Uddin, L. Brinton, J. Nguyen, M. Collins, A. Lodi, S. R. Sweeney, M. Campbell, D. Sweet, A. Sparreboom, R. Lapalombella, S. Tiziani, and S. Baker “Gilteritinib inhibits Glutamine Uptake and Utilization in FLT3-ITD-positive AML”, Molecular Cancer Therapeutics, doi: 10.1158/1535-7163.MCT-21-0071 (2021)

• R. Pandey, M. Collins, X. Lu, S. R. Sweeney, J. Chiou, A. Lodi,  S. Tiziani "Novel Strategy for Untargeted Chiral Metabolomics using Liquid Chromatography-High Resolution Tandem Mass Spectrometry", Analytical Chemistry, 93(14), 5805 (2021)

• S. Stanford#, M. Collins#, M. Diaz, Z. Holmes, P. Gries, M. Bliss, A. Lodi, V. Zhang, S. Tiziani*, N. Bottini* “The low molecular weight protein tyrosine phosphatase promotes adipogenesis and subcutaneous adipocyte hypertrophy”, Journal of Cellular Physiology (2021; #equal contribution first authors, *equal contribution corresponding authors)

2020

• G. L. Hackman, M. Collins, X. Lu, A. Lodi, J. DiGiovanni, S. Tiziani “Predicting and quantifying antagonistic effects of natural compounds given with chemotherapeutic agents: Applications for high throughput-screening”, Cancers, 12(12), 3714 (2020)

• A. Kosti, P. Rosa de Araujo, W.-Q. Li, G. Guardia, J. Chiou, C. Yi, D. Ray, F. Meliso, Y.-M. Li, T. Delambre, M. Qiao; S. S. Burns; F. K. Lorbeer, F. Georgi, M. Flosbach, S. Klinnert, A. Jennseit, X. Lei, C. R. Sandoval, K. Ha, H. Zheng, R. Pandey, A. Gruslova, Y. Gupta; A. Brenner, E. Kokovay, T. R Hughes; Q. Morris, P. Galante, S. Tiziani*, L. O F Penalva* “The RNA binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging “cancer metabolism” and epigenetic regulation”, Genome Biology, 6;21(1):195  (2020; *equal contribution corresponding authors)

• F. Choudhury, G. L. Hackman, A. Lodi, S. Tiziani “Stable isotope tracing metabolomics to investigate the metabolic activity of bioactive compounds for cancer prevention and treatment”, Cancers, 3;12(8):E2147 (2020)

• C. Lu, A. Saha, W. Yan, K. Garrison, C. Lamb, R. Pandey, S. Irani, A. Lodi, X. Lu, S. Tiziani, Y. Zhang, G. Georgiou, J. DiGiovanni, E. Stone “Enzyme-Mediated Depletion of Serum L-Met Abrogates Prostate Cancer Growth via Multiple Mechanisms without Evidence of Systemic Toxicity” PNAS, 117 (23), 13000-13011 (2020)

• S.R. Sweeney, M. Collins, R. Pandey, J. Chiou, A. Lodi, S. Tiziani “Identification of a synergistic combination of dimethylaminoparthenolide and shikonin alters metabolism and inhibits proliferation of pediatric precursor-B cell acute lymphoblastic leukemia” Molecular Carcinogenesis, 59(4), 399-411 (2020)

• R. Pandey, A. Gruslova, J. Chiou, A. J. Brenner, S. Tiziani “Stable Isotope Dilution LC-HRMS Assay to Determine Free SN-38, Total SN-38, and SN-38G in Tumor Xenograft Model after Intravenous Administration of Antibody-Drug Conjugate (Sacituzumab govitecan)” Analytical Chemistry, 92, 1260-1267 (2020)

2019

• M. D. Peris-Díaz, S. R. Sweeney, O. Rodak, E. Sentandreu, S. Tiziani “R-MetaboList 2: a flexible tool for metabolite annotation from high-resolution data-independent acquisition mass spectrometry analysis” Metabolites, 9(9), 187 (2019)

• X. Lu, A. Lodi, M. Konopleva, S. Tiziani “Three-dimensional leukemia co-culture system for in vitro high-content metabolomics screening” SLAS Discovery, 24(8), 817-828 (2019)

• S. Kshattry, A. Saha, P. Gries, S. Tiziani, E. Stone, G. Georgiou, J. DiGiovanni “Targeting antioxidant pathways for suppression of pancreatic tumor growth” Npj Precision Oncology (2019)

• E. Sanchez-Lopez, Z. Zhong, A. Stubelius, S. R. Sweeney, L. M. Booshehri, L. Antonucci, R. Liu-Bryan, A. Lodi, R. Terkeltaub, J. C. Lacal, A. N. Murphy, H. M. Hoffman, S. Tiziani, M. Guma, M. Karin “Choline uptake and metabolism modulate macrophage IL-1β and IL-18 production” Cell Metabolism, 29, 1-13 (2019)

2018

• A. Triplett, K. C. Garrison, N. Marshall, M. Donkor, J. Blazeck, C. Lamb, A. Qerqez, J. Dekker, Y. Tano, W.-Ch. Lu, C. S. Karamitros, K. Ford, B. Tan, M. Zhang, K. McGovern, S. Coma, Y. Kumada, M. S. Yemeny, E. Sentandreu, G. Fromm, S. Tiziani, T. H. Schreiber, M. Manfredi, L. I. R. Ehrlich, E. Stone and G. Georgiou “Reversal of IDO-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzyme” Nature Biotechnology, 36, 758–764 (2018)

• R. Narasimhan, R. Coras, S. Rosenthal, S. Sweeney, A. Lodi, S. Tiziani, D. Boyle, A. Kavanaugh, M. Guma, “Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis” Arthritis Research & Therapy, 20, 164-175 (2018)

• J. R. Molina, Y. Sun, M. Protopopova, S. Gera, M. Bandi, C. Bristow, T. McAfoos, P. Morlacchi, A.-N. A. Agip, G. Al-Atrash, J. Asara, J. Bardenhagen, C. C Carrillo, C. Carroll, E. Chang, S. Ciurea, J. B. Cross, B. Czako, A. Deem, N. Daver, J. Frederick de Groot, J.-W. Dong, N. Feng, G. Gao, J. Gay, M. Geck Do, J. Greer, J. Han, V. K Henry, J. Hirst, S. Huang, Y. Jiang, Z. Kang, S. Konoplev, G. Liu, A. Lodi, T. Lofton, H. Ma, P. Matre, R. Mullinax, M. Peoples, A. Petrocchi, J. Rodriguez-Canale, R. Serreli, T. Shi, M. Smith, J. Theroff, S. Tiziani, Q. Xu, Q. Zhang, F. Muller, R. A. DePinho, C. Toniatti, T. P. Heffernan, G. F. Draetta, M. Konopleva, P. Jones, M. E. Di Francesco and J. R. Marszalek, “An inhibitor of oxidative phosphorylation exploits cancer vulnerability” Nature Medicine, 24, 1036–1046 (2018)

• E. Sentandreu, M. Peris, S. R. Sweeney, J. Chiou, N. Muñoz, S. Tiziani, “A survey of Orbitrap All Ion Fragmentation analysis assessed by an R Metabolist Package to Study Small-molecule Metabolites” Chromatographia, 81(7), 981-994 (2018)

• J. Falconer, A. Murphy, S. Young, S. Tiziani, C. D. Buckley, and M. Guma, “Synovial cell metabolism and chronic inflammation in rheumatoid arthritis” Arthritis & Rheumatology, doi:10.1002/art.40504 (2018)

• R. Pandey, C.L. Riley, E. M. Mills, S. Tiziani, “Highly Sensitive and Selective Determination of Redox States of Coenzymes Q9 and Q10 in Mice Tissues: Application of Orbitrap Mass Spectrometry” Analytica Chimica Acta, 1011, 68-76 (2018)

• J. Bryant, S. Sweeney, E. Sentandreu, M. Shin, H. Ipas, B. Xhemalce, J. Momb, S. Tiziani, and D. Appling, “Deletion of the neural tube defect-associated gene Mthfd1l disrupts one-carbon and central energy metabolism in mouse embryos” Journal of Biological Chemistry, 293(16), 5821-5833 (2018)

• A. Brenner, J. Sun, J. Floyd, R. Zuniga, C. Hart, S. Kroll, L. Fichtel, D. Cavazos, L. Caflisch, A. Gruslova, A. Lodi, S. Tiziani, “Hypoxia Activated Evophosphamide for Treatment of Recurrent Bevacizumab-Refractory Glioblastoma: A phase I surgical study” Neuro-Oncology, https://doi.org/10.1093/neuonc/noy015 (2018)

2017

• J. Jose, C. D. J. Tavares, N. D. Ebelt, A. Lodi, R. Edupuganti, Xuemei Xie, A. K. Devkota, T. S. Kaoud, Carla L. Van Den Berg, E. V. Anslyn, S. Tiziani, C. Bartholomeusz, K. N. Dalby, “Serotonin Analogs as Inhibitors of Breast Cancer Cell Growth” ACS Medicinal Chemistry Letters, 8(10), 1072-1076 (2017)

• K. Lewis, S. Brown, S. Tiziani, R. Carrasco, “Sociocultural Considerations in Juvenile Arthritis: A Review”, Journal of Pediatric Nursing, 37, 13-21 (2017)

• R. Pandey, L. Caflisch, A. Lodi, A. J. Brenner, S. Tiziani, “Metabolomic signature of brain cancer” Molecular Carcinogenesis, 1-17 (2017)

• A. Lodi, A. Saha, X. Lu, B. Wang, E. Sentandreu, M. Collins, M. Kolonin, J. DiGiovanni and S. Tiziani “Combinatorial treatment with natural compounds in prostate cancer inhibits prostate tumor growth and leads to key modulations of cancer cell metabolism” Npj Precision Oncology, 1:18 (2017)  
  Highlights:

  1. College of Natural Sciences News: “Starving Prostate Cancer With What You Eat for Dinner“

  2. College of Pharmacy News: “Starving cancer cells with combinations of natural compounds found in foods“

  3. Downtown Austin Patch: “New UT-Austin Research IDs Compounds That Could Thwart Prostate Cancer“

• X. Lu, A. Solmonson, S. M. Nowinski, E. Sentandreu, A. Lodi, E. M. Mills, S. Tiziani, “The cold-induced early metabolomics response analysis of adipose tissue during acute cold exposure in mice” Scientific Reports, 7, 3455 (2017)

• S. L. Cramer, A. Saha, J. Liu, S. Tadi, S. Tiziani, W. Yan,K. Triplett, C. Lamb, S. E. Alters, S. Rowlinson, Y. J. Zhang, M. J.Keating, P. Huang, J. DiGiovanni, G. Georgiou, and E. Stone “Systemic depletion of serum L-Cyst(e)ine with an engineered human enzyme induces production of reactive oxygen species and suppresses tumor growth in mice” Nature Medicine, 23, 120-127 (2017)

2016

• P. Matre, J. Velez, R. Jacamo, Y.Qi, X. Su, T. Cai, S., Chan, A. Lodi, S. R. Sweeney, H.Ma, R. E. Davis, S. Schindela, T. Haferlach, X. Su, E. R. Flores, D.Gonzalez, S. Konoplev, I. Samudio, C. DiNardo, R. Majeti, A. D. Schimmer, W. Li, T. Wang, S. Tiziani, M. Konopleva “Inhibiting glutaminase in acute myeloid leukemia: Metabolic dependency of selective acute myeloid leukemia subtypes” Oncotarget, 7(48) 79722-79735 (2016)

• L. M. Lashinger, C. H. O’Flanagan, S. M. Dunlap, A. J. Rasmussen, S. Sweeney, J. Y. Guo, A. Lodi, S. Tiziani, E. White and S. D. Hursting, “Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors” Cancer & Metabolism, 4-18 (2016)

• S. R. Sweeney, A. Kavanaugh, A. Lodi, B. Wang, D. Boyle, S. Tiziani*, M. Guma*. “Metabolomic Profiling Predicts outcome of Rituximab therapy in Rheumatoid Arthritis.” Rheumatic and Musculoskeletal Diseases, 2(2) e000289 (2016; *equal contribution corresponding authors)

• M. Guma*, S. Tiziani*, and G. S. Firestein, “Metabolomics in Rheumatoid Arthritis: Desperately Seeking Biomarkers” Nature Reviews Rheumatology 12, 269-281(2016; *equal contribution first authors)

• R. Garcia-Carbonell, A.S. Divakaruni, A. Lodi, I. Vicente-Suarez, A. Saha, H. Cheroutre, G.R. Boss, S. Tiziani, A.N. Murphy, G.S. Firestein, M. Guma, “Critical role of fibroblast-like synoviocytes glycolytic metabolism in rheumatoid arthritis” Annals of the Rheumatic Diseases, 68(7) 1614-1626 (2016)

2015

• R. Sweeney, J. DiGiovanni, S. Tiziani, “Metabolomics, Bioactives, and Cancer.” Genomics, Proteomics, and Metabolomics in Neutraceuticals and Functional Foods (2nd edition), Ed. Bagchi D, Swaroop A, Bagchi M. John Wiley and Sons, West Sussex, United Kingdom. ISBN: 978-1-118-93042-7 (2015).

• M. Guma, E. Sanchez-Lopez, A. Lodi, R. Garcia-Carbonell, S. Tiziani, M. Karin, J. C. Lacal and G. S. Firestein, “Choline kinase inhibition in rheumatoid arthritis” Annals of the Rheumatic Diseases 74(7), 1399-1407 (2015)

• J. Purać, D. Kojić, Ž. Popović, E. Vukašinović, S. Tiziani, U. L. Günther, G. Grubor-Lajšić, “Metabolomic analysis of diapausing and non-diapausing larvae of European corn borer Ostrinia nubilalis” Acta Chimica Slovenica, 62(4), 761-767 (2015)

2014

• Y. Kang, S. Tiziani, G. Park, M. Kaul, G. Paternostro, “Protection using Flt3 and PI3Kα inhibitors demonstrates multiple mechanisms of oxidative glutamate toxicity” Nature Communications, 5:3672 (2014)

• S. Tadi, S. Sweeney, S. Tiziani, “Future Perspectives of Metabolomics in Adipocytes” J. Nutrition Health Food Sci. 2(2): 1-7 (2014)

2013

• S. Tiziani*, Y. Kang, J. Axelrod, R. Harjanto, C. Piermarocchi, W. Roberts, G. Paternostro*, “Metabolomics of the tumor microenvironment in childhood lymphoblastic leukemia” PLoS ONE 8(12), e82859 (2013) (*equal contribution corresponding authors)

• A. Lodi*, S. Tiziani*, F. L. Khanim, U. L. Günther, M. R. Viant, C. M. Bunce, M. T. Drayson “Proton NMR-based metabolic analyses of MRC Myeloma IX serum samples identifies carnitine and acetyl carnitine as novel markers of active disease and demonstrate the value of non empirically presumed poor quality archived patient material” PLoS ONE 8(2), e56422 (2013) (*equal contribution)