Neuro-Epitranscriptomics: Measuring RNA Modifications in the Brain and Single Neurons
Kevin Clark, Assistant Professor, Department of Chemistry, Tufts University
Macrocyclic DELs and Their Utility in Discovery of Mcl-1Inhibitors
Matt Clark, CSO, X-Chem
Exploring the evolution of obesity treatments: from GLP-1 agonists to polypharmacy approaches
Florence Brunel, Senior Principal Scientist, Novo Nordisk
Identifying novel ionizable lipids for non-viral mRNA delivery
Eric Dane, Associate Principal Scientist, Advanced Drug Discovery, AstraZeneca
Molecular Design and Repair of Peptide Therapeutics
Krishna Kumar, Tufts University
Targeting Protein Misfolding Using Semisynthesis of a Molecular Chaperone
Aaron Petty (Oleta Johnson Lab), MIT
Chemically Expanded Yeast Display: Covalent Antibodies and More
James A. Van Deventer, Tufts University
Harnessing the Power of the Epigenome
Amanda Green, Omega Therapeutics
Bachem’s Perspective: Scale-up Manufacturing of TIDES
Keith Porter, Bachem
Development and Optimization of the Endosomal Escape Vehicle (EEV™) Platform to Enhance the Intracellular Delivery of Oligonucleotides
Mah Kheirabadi, Entrada Therapeutics
Divergent Trafficking of Parathyroid Hormone Receptor Type 1 by α/β-Peptide Agonist
Tae Wook Kim. Gellman Lab, University of Wisconsin
Mixed-Mode Reverse-Phase Chromatography: Theory and Application To Peptides and Oligonucleotides
Timothy O’Mara, Itochu
Engineering Peptides at the Speed of Light: High-throughput Discovery and Parallel Optimization of Peptide Therapeutics
Geoff Eddinger, Nimble Therapeutics
Biocatalysis Beyond Tryptophan
Wendy Hartsock, Aralez Bio
Peptide–Oligonucleotide Conjugate Synthetic Strategies
Andy Yan, CPC
Dillon Flood & Kyle Knouse, Elsie Biotechnologies
Katarzyna “Kasha” Slowinska, CSU, Long Beach
John Phipps, CPC Scientific
Devin Swanson, Janssen
Corwin Nycholat, Sussex Research
Discovery of Zilucoplan: A Potent Macrocyclic Peptide Complement Component 5, C5, Inhibitor in Acetylcholine Receptor Antibody-positive Generalized Myasthenia Gravis
Ping Ye, UCB
Multiscale Simulations of Biomolecular Condensates with ML Force Fields
Bin Zhang, MIT
A Half Century Journey Through Academics, Pharma, and Biotech in Pursuit of Miraculous Molecules
Richard DiMarchi, Indiana Univeristy
Measuring the Synthetic Peptide Waste-Line
Michael Kopach, Eli Lilly
Engineering Enzymes for Green Manufacturing of Noncanonical Amino Acids
Tina Boville, Aralez Bio
Peptide Production Re-invented: Harnessing AI-based robotics for industry changing, fully automated peptide production
Dale Thomas, Mytide
Multiplexing platforms for the discovery of Helicon peptide therapeutics
John McGee, FogPharma
An Overview of DNA-encoded Libraries: Our Perspective
Paige Dickson, X-Chem
Computational prediction of cyclic peptide structural ensembles and application to the design of Nrf2–Keap1 inhibitors
Francini Fonseca, Krizer Lab - Lin Lab, Tufts University
Targeting cardiovascular disease with anti-microRNA peptide nucleic acid conjugates
Sarah Antilla, Pentelute Lab, MIT
Generation of Proteins with Free N-Terminal Cysteine by Aminopeptidases
Jordan Hempfling, Mariana Oncology
Christina Schroeder, Genentech
Dinah Misner, Aligos Therapeutics
Dale Thomas, Mytide Therapeutics
Kaustav Biswas, Director, Discovery Chemistry, Merck & Co., Inc
Alex Callahan, MIT
Stalking Elusive Pathogenic Bacteria: How to Dive into Cells to Treat Infections
Jean Chmielewski, Purdue University
New Developments in Solid Phase Peptide Chemistry Facilitate the Study of Protein Prenylation
Taysir Bader, University of Minnesota
Neoantigens: what are they and why are they so important for next-generation cancer immuno-therapy?
Daniel DeOliveira, Life Sciences Project Mgmt
Endosomal Escape Vehicle (EEVTM) Platform for Enhanced Functional Delivery of Oligonucleotides
Leo (Ziqing) Qian, Entrada Therapeutics
Laura Kiesling, MIT
DNA-encoded libraries of synthetic peptides for ligand optimization and activity-based probes
Casey Krusemark, Purdue University
Quantification of Diastereomer Impurities in Teduglutide API
John Phipps, CPC