This page explains how thyroid medications work, how doses are adjusted, and what to expect when taking medicines for hypothyroidism or hyperthyroidism.
If you have a thyroid condition, medication is often part of the treatment.
This page explains:
The most common thyroid medicines
What they do
How they are used
What to expect
All in simple, clear language.
Thyroid medicines are used for two main reasons:
To replace missing thyroid hormone
To slow down an overactive thyroid
The type of medicine depends on whether your thyroid is:
Too slow (hypothyroidism)
Too fast (hyperthyroidism)
The main treatment for hypothyroidism is:
➡ Thyroid hormone replacement
Synthroid
Levoxyl
Unithroid
Euthyrox
Levothyroxine is a man-made version of T4, the hormone your thyroid normally produces.
It:
Replaces missing thyroid hormone
Brings TSH back to normal
Relieves hypothyroid symptoms
Restores normal metabolism
For most people, this is the only medicine needed.
One pill daily
Usually first thing in the morning
On an empty stomach
With water
At the same time each day
Consistency is very important.
Blood levels improve in about 4–6 weeks
Symptoms improve gradually
Full effect may take 6–8 weeks
Doses are adjusted based on TSH results.
Some people use:
Liothyronine (T3 medication)
Combination T4/T3 therapy
Natural desiccated thyroid (like Armour Thyroid)
These are used in specific situations but are less common.
If your thyroid is overactive, the goal is the opposite:
➡ Slow the thyroid down
The two main medicines are:
Methimazole
Propylthiouracil (PTU)
They:
Block the thyroid from making too much hormone
Gradually bring levels back to normal
Help control hyperthyroidism
Sometimes short term
Sometimes for 1–2 years
In some people, long term
Treatment plans depend on the cause of hyperthyroidism.
These are not thyroid medicines, but they help symptoms.
Examples:
Propranolol
Atenolol
Metoprolol
They help with:
Fast heartbeat
Tremors
Anxiety
Sweating
They make people feel better while thyroid levels are being fixed.
Medication doses are not “one size fits all.”
Doctors adjust based on:
TSH levels
Free T4 levels
Age and health conditions
It often takes a few adjustments to find the perfect dose.
Typical schedule:
Every 6–8 weeks when starting or changing doses
Every 6–12 months once stable
Regular monitoring keeps levels safe and steady.
For best results:
Take it at the same time every day
Don’t skip doses
Avoid taking with food
Wait 30–60 minutes before eating
Keep supplements like calcium or iron at least 4 hours apart
These small habits make a big difference.
It depends.
Hypothyroidism from Hashimoto’s is usually lifelong
Temporary thyroiditis may not need long-term meds
Hyperthyroidism treatment plans vary
Never stop thyroid medicine without talking to your doctor.
Most thyroid medicines are very well tolerated.
Possible issues can include:
Dose being too high or too low
Temporary symptoms while adjusting
Rare allergic reactions
True side effects are uncommon when levels are monitored.
If you start thyroid medication, the usual plan is:
Begin at a starting dose
Recheck labs in 6–8 weeks
Adjust if needed
Continue regular monitoring
Most people feel much better once the right dose is found.
Low thyroid is treated with hormone replacement
High thyroid is treated with anti-thyroid meds or other therapies
Medications are safe and effective
Doses are personalized
Regular blood tests are essential
The next page will cover:
➡ Thyroid Diet & Supplements Explained
(what really helps – and what doesn’t)