This page explains how a thyroid fine needle aspiration biopsy is done, what the different biopsy results mean, and how doctors use FNA to check if a thyroid nodule is benign or cancerous.
If an ultrasound shows a thyroid nodule that needs more evaluation, your doctor may recommend:
➡ A thyroid biopsy, also called Fine Needle Aspiration (FNA).
This sounds scary, but it is a very common, simple, and safe test.
A thyroid biopsy uses a very thin needle to collect a few cells from a thyroid nodule.
Those cells are then looked at under a microscope to see if they are:
Benign (non-cancerous)
Suspicious
Cancerous
It is the best way to know what a nodule really is.
Most thyroid nodules are harmless.
But doctors recommend a biopsy when:
A nodule is above a certain size
The ultrasound looks suspicious
The nodule has grown
You have risk factors for thyroid cancer
The goal is to be cautious and get clear answers.
A biopsy is usually considered if a nodule is:
Larger than about 1 centimeter
Solid instead of fluid-filled
Irregular in shape
Growing over time
Showing certain features on ultrasound
Small, simple nodules often do not need biopsy.
Here’s exactly what to expect:
You lie down with your neck slightly extended
The skin is cleaned
Ultrasound is used to guide the needle
A very thin needle is inserted into the nodule
A few tiny samples are taken
The whole process usually takes 10–20 minutes
Most people say it feels like a quick pinch.
Usually:
Only mild discomfort
Similar to having blood drawn
No need for general anesthesia
You can go home right after.
The collected cells are sent to a lab where a specialist (a pathologist) examines them.
Results usually come back in:
➡ About 1–2 weeks
Biopsy results usually fall into one of these categories:
The nodule is not cancer
No surgery needed
Usually just monitoring over time
Thyroid cancer is found
Treatment is planned, usually surgery
The good news:
Most thyroid cancers are very treatable.
Cells don’t look clearly normal or clearly cancer
More testing or repeat biopsy may be needed
Sometimes surgery is recommended to be safe
Not enough cells were collected
The biopsy may need to be repeated
No.
Thyroid biopsies do not spread cancer.
They are considered very safe and have been used for many years.
After a biopsy you may have:
Mild soreness
A small bruise
Slight tenderness
Most people return to normal activities the same day.
Serious complications are very rare.
Usually no treatment needed
Periodic ultrasounds to monitor
Referral to a thyroid specialist
Discussion of surgery
Very good long-term outlook in most cases
Repeat biopsy
Special genetic testing
Discussion of options
The plan after a biopsy depends completely on the result.
But remember:
➡ The vast majority of thyroid biopsies come back benign.
FNA biopsy checks thyroid nodules
It is quick, safe, and minimally painful
It helps rule out cancer
Most results are benign
It guides the best treatment plan
The next page will explain:
(what it really means and why the outlook is usually very good)