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Global Digital PCR Market is valued at USD 428.7 Million in 2019 and expected to reach USD 1312.3 Million by 2025 with the CAGR of 17.33% over the forecast period.
Growing prevalence of chronic diseases is one of the major factors expected to drive the Global Digital PCR Market.
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Digital polymerase chain reaction which is also known as digital PCR or dPCR is refinement technique with the help of biotechnology of conventional polymerase chain reaction procedures that can be applied to directly quantify and clonally amplify nucleic acids strands containing DNA, cDNA, or RNA. The key dissimilarity between dPCR and traditional PCR lies in the process of measuring nucleic acids amounts, where dPCR being a more precise method than PCR, even if error can be more in the hands of inexperienced users. A "digital" measurement system quantitatively and discretely measures a certain number of variables, whereas an “analog” measurement generates certain measurements based on already measured patterns. PCR carries out one reaction per single sample and dPCR also carries out a single reaction within a sample, but the sample is separated into a large number of partitions and the reaction is done in each partition individually. This separation enables a more reliable collection and sensitive measurement of nucleic acid amounts. The method is useful for studying variations in gene sequences such as copy number variants and point mutations and it has routine application used for clonal amplification of samples for next-generation sequencing.
Some major key players for global Digital PCR market are,
Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, JN Medsys, RainDance Technologies Inc., Stilla, Fluidigm Corporation, QIAGEN, Merck KGaA, Avance Biosciences, Others.
Global Digital PCR Market is segmented on the basis of product type, technology, application and region & country level. Based on product type, global digital PCR market is classified as digital PCR equipment, consumables and reagents and software & services. Based upon technology, the market is classified into droplet digital PCR and beaming digital PCR. Based upon application, global digital PCR market is classified into clinical diagnostics, forensics, research and others.
The regions covered in this digital PCR market report are North America, Europe, Asia-Pacific and Rest of the World. On the basis of country level, market of digital PCR is sub divided into U.S., Mexico, Canada, U.K., France, Germany, Italy, China, Japan, India, South East Asia, GCC, Africa, etc.
Global Digital PCR Market Segmentation:–
By Product Type: Digital PCR Equipment, Consumables and Reagents, Software and Services
By Application: Clinical Diagnostics, Forensics, Research, Others
Global Digital PCR Market Dynamics–
The major factors contributing to the growth of the digital PCR market is increasing diagnostic and screening test due to prevalence of chronic diseases such as cancer, growing occurrences of hereditary and infectious diseases, increasing research on gene based studies and technological improvement in the field of biotechnology. According to World Cancer Research Fund, there were about 18 million cancer cases around the world in 2018, of these 9.5 million cases were found in men and 8.5 million in women. According to World Health Organization (WHO), worldwide 1 in 6 deaths are due to cancer. So to prevent cancer from spreading, early detection is necessary for which demand of digital PCR is growing worldwide. It has the capability to detect rare sequences such as HIV DNA in patients with HIV, and DNA from fecal bacteria in ocean and other water samples for measuring water quality. It can detect sequences as rare as 1 in every 1,250,000 cells for which it is widely used in genetic related research activities. dPCR is also used in liquid biopsy due to its ability to detect rare mutations which benefits the clinic to detect cancer, degree of tumor infection and disease progression. All these applications of digital PCR are supplementing it’s demand worldwide. However, the high instrument costs associated with dPCR and the technical limitations of PCR is restraining the market growth up to some extent.
Global Digital PCR Market Regional Analysis–
North America is dominating the digital PCR market with highest share due to growing prevalence of chronic diseases such as cancer, HIV, hepatitis etc., increasing adoption of novel genomic analysis products, high investment for genomic research and growing use of dPCR in healthcare industry in this region. For instance; the American Cancer Society has projected 1,762,450 new cancer cases and 606,880 cancer deaths in the United States in 2019 and for early prevention, healthcare sector will have more demand on advanced technology such as digital PCR.
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