PUBLICATIONS
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Publications at NBRC
2026
Sharma S, Ponniah K, Bandyopadhyay I, Vadawale D, Koushika SP, Ghosh-Roy A. Worm orthologues of cytokinesis-associated proteins CIT and ASPM regulate neuronal microtubule dynamics and polarity in C. elegans. PLoS Genet. 2026 Apr 15;22(4):e1012106. doi: 10.1371/journal.pgen.1012106. Epub ahead of print. PMID: 41984993.
Singh P, Vasudevan M, Dey S, Selvarasu K, Balakrishnan S, Bassi D, Ghosh-Roy A. The conserved fibroblast growth factor receptor-based signaling is required for dendrite regeneration. Proc Natl Acad Sci U S A. 2026 Mar 24;123(12):e2506886123. doi: 10.1073/pnas.2506886123. Epub 2026 Mar 18. PMID: 41849383; PMCID: PMC13016080.
2025
Dhar K, Jena KK, Mehto S, Sahu R, Murmu KC, Mahajan AA, Behera S, Putchala RK, Mathew RJ, Bal R, Kundu S, Das SK, Chauhan S, Satapathy S, Yadav R, Priyadarsini S, Padala KR, Namdigalla P, Mishra S, Muralidhara P, Bansal K, Sannula K, Prasad P, Bokara KK, Sowpati DT, Ghosh-Roy A, Mahapatra PK, Khadilkar RJ, Yelagandula R, Chauhan S. Programmed cell revival from imminent cell death enhances tissue repair and regeneration. EMBO J. 2025 Oct;44(19):5244-5289. doi: 10.1038/s44318-025-00540-y. Epub 2025 Aug 21. PMID: 40841709; PMCID: PMC12489119.
Brar HK, Bassi D, Ghosh-Roy A. Analysis and Quantification of Functional Regeneration of Dendrite and Axon of PVD Neuron After Laser Injury in Caenorhabditis elegans. Bio Protoc. 2025 Apr 20;15(8):e5280. doi: 10.21769/BioProtoc.5280. PMID: 40291422; PMCID: PMC12021587.
Ravivarma S, Behera S, Roy D, Ghosh-Roy A. Independent control of functional rewiring after axon injury by let-7 miRNA and insulin/insulin-like growth factor signaling pathways. J Biosci. 2025;50:24. PMID: 40202232.
2024
Brar HK, Dey S, Singh P, Pande D, Ghosh-Roy A. Functional Recovery Associated with Dendrite Regeneration in PVD Neuron of Caenorhabditis elegans. eNeuro. 2024 May 21;11(5):ENEURO.0292-23.2024. doi: 10.1523/ENEURO.0292-23.2024. PMID: 38548333; PMCID: PMC7615967.
Dey S, Kumar N, Balakrishnan S, Koushika SP, Ghosh-Roy A. KLP-7/Kinesin-13 orchestrates axon-dendrite checkpoints for polarized trafficking in neurons. Mol Biol Cell. 2024 Sep 1;35(9):ar115. doi: 10.1091/mbc.E23-08-0335. Epub 2024 Jul 10. PMID: 38985513; PMCID: PMC7616348.
Singh P, Selvarasu K, Ghosh-Roy A. Optimization of RNAi efficiency in PVD neuron of C. elegans. PLoS One. 2024 Mar 18;19(3):e0298766. doi: 10.1371/journal.pone.0298766. PMID: 38498505; PMCID: PMC10947639.
Ray P; Rao PT; Nandi M; Haque A; Mitra S; Raychaudhary S; Ghosh-Roy A; Polley S"Activation and regulation of a p38α MAPK by its downstream MAPKAP kinase through feedback phosphorylation and LLPS-driven condensate formation" BioRxiv doi.org/10.1101/2024.08.01.606155
2023
Puri D, Sharma S, Samaddar S, Ravivarma S, Banerjee S, Ghosh-Roy A. Muscleblind-1 interacts with tubulin mRNAs to regulate the microtubule cytoskeleton in C. elegans mechanosensory neurons. PLoS Genet. 2023 Aug 21;19(8):e1010885. doi: 10.1371/journal.pgen.1010885. PMID: 37603562; PMCID: PMC10470942.
2022
Brar HK, Dey S, Bhardwaj S, Pande D, Singh P, Dey S, Ghosh-Roy A. Dendrite regeneration in C. elegans is controlled by the RAC GTPase CED-10 and the RhoGEF TIAM-1. PLoS Genet. 2022 Mar 28;18(3):e1010127. doi: 10.1371/journal.pgen.1010127. PMID: 35344539; PMCID: PMC8989329.
2021
Dey S, Ghosh-Roy A. In vivo Assessment of Microtubule Dynamics and Orientation in Caenorhabditis elegans Neurons. J Vis Exp. 2021 Nov 20;(177):10.3791/62744. doi: 10.3791/62744. PMID: 34866634; PMCID: PMC7614928.
Kulkarni SS, Sabharwal V, Sheoran S, Basu A, Matsumoto K, Hisamoto N, Ghosh-Roy A, Koushika SP. UNC-16 alters DLK-1 localization and negatively regulates actin and microtubule dynamics in Caenorhabditis elegans regenerating neurons. Genetics. 2021 Nov 5;219(3):iyab139. doi: 10.1093/genetics/iyab139. PMID: 34740241; PMCID: PMC8570795.
Basu A, Behera S, Bhardwaj S, Dey S, Ghosh-Roy A. Correction: Regulation of UNC-40/DCC and UNC-6/Netrin by DAF-16 promotes functional rewiring of the injured axon. Development. 2021 Aug 1;148(15):dev200008. doi: 10.1242/dev.200008. Epub 2021 Aug 9. Erratum for: Development. 2021 Jun 1;148(11):dev198044. doi: 10.1242/dev.198044. PMID: 34370007; PMCID: PMC11106660.
Kumar S, Behera S, Basu A, Dey S, Ghosh-Roy A. Swimming Exercise Promotes Post-injury Axon Regeneration and Functional Restoration through AMPK. eNeuro. 2021 Jun 16;8(3):ENEURO.0414-20.2021. doi: 10.1523/ENEURO.0414-20.2021. PMID: 34031101; PMCID: PMC8211466.
Puri D, Ponniah K, Biswas K, Basu A, Dey S, Lundquist EA, Ghosh-Roy A. Wnt signaling establishes the microtubule polarity in neurons through regulation of Kinesin-13. J Cell Biol. 2021 Sep 6;220(9):e202005080. doi: 10.1083/jcb.202005080. Epub 2021 Jun 17. PMID: 34137792; PMCID: PMC8217938.
Kadam NY, Behera S, Kumar S, Ghosh-Roy A, Babu K. The G-Protein-Coupled Receptor SRX-97 Is Required for Concentration-Dependent Sensing of Benzaldehyde in Caenorhabditis elegans. eNeuro. 2021 Jan 28;8(1):ENEURO.0011-20.2020. doi: 10.1523/ENEURO.0011-20.2020. PMID: 33397797; PMCID: PMC7877458.
2019
Pratima Pandey, Anuradha Singh, Harjot Kaur, Anindya Ghosh-Roy and Kavita Babu (2019); Loss of dop-2 causes increased dopamine release and locomotory defects in the presence of ethanol. BioRxiv 2019 Sep 23. https://www.biorxiv.org/content/10.1101/779405v1.
2017
Basu A, Dey S, Puri D, Das Saha N, Sabharwal V, Thyagarajan P, Srivastava P, Koushika SP, Ghosh-Roy A. let-7 miRNA controls CED-7 homotypic adhesion and EFF-1-mediated axonal self-fusion to restore touch sensation following injury. Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10206-E10215. doi: 10.1073/pnas.1704372114. Epub 2017 Nov 6. PMID: 29109254; PMCID: PMC5703274.
Past Selected Publications:
FACULTY of 1000 evaluation
Chen L, Wang Z, Ghosh-Roy A, Hubert T, Yan D, O'Rourke S, Bowerman B, Wu Z, Jin Y, Chisholm AD. Axon regeneration pathways identified by systematic genetic screening in C. elegans. Neuron. 2011 Sep 22;71(6):1043-57. doi: 10.1016/j.neuron.2011.07.009. Epub 2011 Sep 21. PMID: 21943602; PMCID: PMC3183436.
Ghosh-Roy A, Chisholm AD. Caenorhabditis elegans: a new model organism for studies of axon regeneration. Dev Dyn. 2010 May;239(5):1460-4. doi: 10.1002/dvdy.22253. PMID: 20186917; PMCID: PMC3069807.
Ghosh-Roy A, Wu Z, Goncharov A, Jin Y, Chisholm AD. Calcium and cyclic AMP promote axonal regeneration in Caenorhabditis elegans and require DLK-1 kinase. J Neurosci. 2010 Mar 3;30(9):3175-83. doi: 10.1523/JNEUROSCI.5464-09.2010. PMID: 20203177; PMCID: PMC2921707.
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