publications

18. Lee, J.-H.; Lee, J.-E.; Son, S.-E.; Son, S. H.; Kim, N.-J.; Im, D.-S. NKJ14047 inhibition of p38 MAPK ameliorates inflammatory immune diseases by suppressing T cell differentiation. Int. Immunopharmacol., 2024, 130, 111800.

17. Yoo, H.-S.; Shin, J.-W.; Jang Y. H.; Yang Y.-S.; Son, S. H.; Won, H.-J.; Kim, S. L.; Sim, J.; Kim N.-J. Synthesis of 2,3-Benzotropones via Palladium(II)-Catalyzed Aerobic Dehydrogenation from 1-Benzosuberones and Sequential Diels-Alder Reaction to Yield Benzobicyclo[3,2,2]nonenones, J. Org. Chem., 2024, 89, 3102–3110. 

16. Son, S. H.‡; Lee, N.-R.‡; Gee, M. S.‡; Song, C W.; Lee, S. J.; Lee, S.-K.; Lee, Y.; Kim, H.; Lee, J.-K.; Inn, K.-S.; Kim, N.-J. Chemical Knockdown of Phosphorylated p38 Mitogen-Activated Protein Kinase (MAPK) as a Novel Approach for the Treatment of Alzheimer’s Disease, ACS Cent. Sci., 2023, 9, 417–426. [IF: 18.2]

15. Lee, J.-H.; Son, S. H.; Kim, N.-J.; Im, D.-S. NJK14047 Suppression of the p38 MAPK Ameliorates OVA-Induced Allergic Asthma during Sensitization and Challenge Periods, Biomol. Ther., 2023, 31, 183–192.

14. Jang, Y. H.; Yang, Y.-S.; Son, S. H.; Yoo, H.-S.; Shin, J.-W.; Choi, J.-W.; Kim, S. L.; Lim, C.; Kim, N.-J. Synthesis of Xanthones via Copper(II)-Catalyzed Dehydrogenative Cyclization and Successive Aromatization in a One Step Sequence, Org. Lett., 2022, 24, 9216–9221.

13. Yang, Y.‡; Lee, S.‡; Son, S. H.; Yoo, H.-S.; Shin, J.-W.; Choi, J.-W.; Kim, S. L.; Sim, J.; Kim, N.-J. Ligand-controlled regiodivergent direct arylation of indoles via oxidative boron Heck reaction, Org. Chem. Front., 2022, 9, 5906–5911.

12. Lee, J.-H.; Son, S. H.; Kim, N.-J.; Im, D.-S. p38 MAPK Inhibitor NJK14047 Suppresses CDNB-Induced Atopic Dermatitis-Like Symptoms in BALB/c Mice, Biomol. Ther., 2022, 30, 501–509.

11. Cho, E.; Youn, K.; Sin, J. S.; Cho, W, S.; Park, S. J.; Ryu, J. H.; Son, S. H.; Jang, D. S.; Shin, C. Y.; Moon, M.; Jun, M. Kim, N.-J.; Kim, D. H. Eugenitol ameliorates memory impairments in 5XFAD mice by reducing Aβ plaques and neuroinflammation, Biomed. Pharmacother., 2022, 148, 112763.

10. Yoo, H.-S.‡; Yang, Y.‡; Kim, S. L.; Jang, Y. H.; Son, S. H.; Shin J. W.; Kim, N.-J. Syntheses of 1H-Indoles, Quinolines, and 6-Membered Aromatic N-Heterocycle-Fused Scaffolds via Palladium(II)-Catalyzed Aerobic Dehydrogenation under Alkoxide-Free Conditions, Chem. Asian J., 2021, 21, 3469–3475.

9. Son, S. H.‡; Shin, J. W.‡; Won, H.-J.; Yoo, H.-S.; Cho, Y. Y.; Kim, S. L.; Jang, Y. H.; Park, B. Y.; Kim, N.-J. Synthesis of meta-(Indol-3-yl)phenols from Indoles and Cyclohexenone via Palladium(II)-Catalyzed Oxidative Heck Reaction and Dehydrogenative Aromatization in a One Step Sequence, Org. Lett., 2021, 23, 7467–7471. [IF: 6.005]

8. Son, S. H.‡; Do, J.‡; Yoo, J.-N.‡; Lee, H.; Kim, N.; Yoo, H.-S.; Gee, M.; Kim, J.-H.; Seong, J.-H.; Inn, K.-S.; Seo, M.-D.; Lee, J.-K.; Kim, N.-J. Identification of ortho-catechol containing isoflavone as a privileged scaffold that directly prevents the aggregation of both amyloid β plaques and tau-mediated neurofibrillary tangles and its in vivo evaluation, Bioorg. Chem., 2021, 113, 105022. [IF: 5.275]

7. Kim, G.-Y.‡; Song C.-W.‡; Yang, Y. S.; Lee, N.-R.; Yoo, H.-S.; Son, S. H.; Lee, S.-J.; Park, J.-S.; Lee, J.K.; Inn, K.-S.; Kim, N.-J. Chemical Degradation of Androgen Receptor (AR) Using Bicalutamide Analogue—Thalidomide Conjugates, Molecules, 2021, 26, 2525.

6. Son, S. H.‡; Cho, Y. I.‡; Yoo, H.-S.; Lee, S.-J.; Kim, Y.-M.; Jang, H.; Kim, D. H.; Shin, J.-W.; Kim, N.-J. Divergent Synthesis of Flavones and Flavanones from 2'-Hydroxydihydrochalcones via Palladium(II)-Catalyzed Oxidative Cyclization, RSC Adv., 2021, 11, 14000–14006. [IF: 4.036]

5. Kim, Y.-M.‡; Yoo, H.-S.‡; Son, S. H.; Kim, G.; Jang H.-J.; Kim, D.-H.; Kim, S. D.; Park, B. Y.; Kim, N.-J. A Novel Approach to N-Tf 2-Aryl-2,3-Dihydroquinolin-4(1H)-ones via a Ligand Free Pd(II)-Catalyzed Oxidative Aza-Michael Cyclization, Eur. J. Org. Chem., 2021, 2021, 618–622.

4. Gee, M. S.‡; Son, S. H.‡; Jeon, S. H.; Do, J.; Kim, N.; Ju, Y.-J.; Lee, S. J.; Inn, K.-S.; Kim, N.-J.; Lee, J. K. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse. Alzheimer Res. Ther., 2020, 12, 45. [IF: 6.982]

3. Yoo, H.-S.; Son, S. H.; Cho, Y. Y.; Lee, S.-J.; Jang, H.; Kim, Y.-M.; Kim, D. H.; Kim, N. Y.; Park, B. Y.; Lee, Y. S.; Kim, N.-J. Synthesis of Flavanones via Palladium (II)-Catalyzed One-Pot β-Arylation of Chromanones with Aryl Boronic Acids, J. Org. Chem., 2019, 84, 10012–10023.

2. An, J.-Y.‡; Lee, H.-H.‡; Shin, J.-S.; Yoo, H. S.; Park, J.-S.; Son, S. H.; Kim, S. W.; Yu, J.; Lee, J.; Lee, K.-T.; Kim, N.-J. Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE2 in LPS-induced RAW 264.7 cells, Bioorg. Med. Chem. Lett., 2017, 27, 2613–2616.

1. Lee, J.‡; Yu, J.‡; Son, S. H.; Heo, J.; Kim, T.; An, J.-Y.; Inn, K.-S.; Kim, N.-J. A versatile approach to flavones via one-pot Pd(II)-catalyzed dehydrogenation/oxidative boron-Heck coupling sequence of chromanones, Org. Biomol. Chem., 2016, 14, 777–784.