Peer Reviewed Papers

Below, you’ll find my peer reviewed publication organized by year. For questions on any specific publication, feel free to message my office.

Gasmi-Seabrook, G.M.C., Howarth, J.W., Finley, N., Abusamhadneh, E., Gaponenko, V., Brito, R. R. M., Solaro, R.J. and Rosevear, P.R. (1999) Solution Structures of the C- Terminal Domain of Cardiac Troponin C Free and Bound to the N- Terminal Domain of Cardiac Troponin I. Biochemistry 38, 8313-8322.

Gaponenko, V., Abusamhadneh, E., Abbott, M.B., Finley, N., Gasmi-Seabrook, G., Solaro, R.J., Rance, M. and Rosevear, P.R. (1999) Communication: Effects of Troponin I Phosphorylation on Conformational Exchange in the Regulatory Domain of Cardiac Troponin C. J. Biol. Chem. 274, 16691-16684.

Finley, N., Abbott, M.B., Abusamhadneh, E., Gaponenko, V., Dong, W.J., Gasmi-Seabrook, G., Howarth, J.W., Rance, M., Solaro, R.J., Cheung, H.C. and Rosevear, P.R. (1999) NMR Analysis of Cardiac Troponin I Complexes: Effects of Phosphorylation. FEBS Letters 453, 107-112.

Finley, N., Dvoretsky, A. and Rosevear, P.R. (2001) Magnesium-Calcium Exchange in Cardiac Troponin C Bound to Cardiac Troponin I. J. Mol. Cellular Cardiology 32, 1439-1446.

Abbott, M.B., Gaponenko, V., Abusamhadneh, E., Finley, N., Li, G., Dvoretsky, A., Rance, M., Solaro, R.J. and Rosevear, P.R. (2000) Regulatory Domain Conformational Exchange and Linker Region Flexibility in Cardiac Troponin C Bound to Cardiac Troponin I. J. Biol. Chem. 275, 20610-20617.

Abusamhadneh, E., Abbott, M.B., Dvoretsky, A., Finley, N., Sasi, S. and Rosevear, P.R.

(2001) Interaction of Bepridil with the Cardiac Troponin C – Troponin I Complex. FEBS Letters 506, 51-54.

Heller, W.T., Abusamhadneh, E., Finley, N., Rosevear, P.R. and Trewhella, J. (2002) The solution structure of a cardiac troponin C-troponin I-troponin T complex shows a somewhat compact troponin C interacting with an extended troponin I-troponin T. Biochemistry 41, 15654-15663.

Heller, W.T., Finley, N.L., Dong, W.J., Timmins, P. Cheung, H.C., Rosevear, P.R. and Trewhella, J. (2003) Small-angle neutron scattering with contrast variation reveals spatial relationships between the three subunits in the ternary cardiac troponin complex and the effects of troponin I phosphorylation. Biochemistry 42 (25), 7790-7800.

Rosevear PR, Finley N. (2003) Molecular mechanism of levosimendan action: an update. J Mol Cell Cardiol. 35(9):1011-5.

Finley, N.L., Howarth, J. W. and Rosevear, P.R. (2004) Structure of the Mg2+ - Loaded C-Domain of Cardiac Troponin C Bound to the N-Domain of Cardiac Troponin I: Comparison with the Ca 2+ -Loaded Structure. Biochemistry, 43 (36), 11371-11379.

Finley, N.L. and Rosevear, P.R. (2004) Introduction of negative charge mimicking PKC phosphorylation of cardiac troponin I: Effects on cardiac troponin C. J. Biol. Chem. 279(52):54833-40.

Sakthivel S., Finley N.L., Rosevear P.R., Lorenz J.N., Gulick J., Kim S., VanBuren P., Martin L.A., Robbins J. (2005) In vivo and in vitro analysis of cardiac troponin I phosphorylation J Biol. Chem. 280(1):703-14.

Sakthivel S., Finley N.L., Howarth J.W., Osinska H, Klevitsky R., Lorenz J.N., Rosevear P.R. and Robbins J. (2008) Conserved Acidic-N’-region of Cardiac Troponin I is Critical in Regulating Myocardial Function. FASEB J. Apr;22(4):1246-57.

Finley N.L., Cuperman T.I. (2014). Cardiac Myosin Binding Protein C: A Structurally Dynamic Regulator of Myocardial Contractility. Pflügers Archiv. doi 10.1007/s00424-014-1451-0.

Springer T.I., Goebel E., Hariraju D., Finley N.L. (2014) Mutation in the β-hairpin of the

Bordetella pertussis adenylate cyclase toxin modulates N-lobe conformation in calmodulin. Biochem Biophys Res Commun. Oct 10;453(1):43-8.

Kuster D.W., Govindan S., Springer T.I., Martin J.L., Finley N.L., Sadayappan S. (2015) A hypertrophic cardiomyopathy-associated MYBPC3 mutation common in populations of South Asian. J. Biol. Chem. Jan 12, doi:10.1074/jbc.M114.607911.

Springer, T. I., Emerson, C. C., Johns, C. W., Finley, N. L. (2016) Interaction with adenylate cyclase toxin from Bordetella pertussis affects the metal binding properties of calmodulin. FEBS Open Bio, 7: 25–34. doi:10.1002/2211-5463.12138.

Springer, T.I., Johns, C.W., Cable, J., Lee, A.B., Lin, B., Sadayappan, S., Finley, N.L. (2017) Calcium-dependent interaction occurs between slow skeletal myosin binding protein c and calmodulin. Magnetochemistry, 4(1), 1; doi:10.3390/magnetochemistry4010001.

Johns, C.W., Lee, A.B., Springer, T.I., Rosskopf, E.N, Hong, J.C., Turechek, W., Kokalis-Burelle, N., Finley, N.L. (2017) Using NMR-based metabolomics to monitor the biochemical composition of agricultural soils: A pilot study. Eur J Soil Biol, 83: 98-105. doi.org/10.1016/j.ejsobi.2017.10.008

Johns C.W., Finley, N.L. (2017) Site I inactivation impacts calmodulin calcium binding and activation of Bordetella pertussis adenylate cyclase toxin. Toxins, 9, 389, doi:10.3390/toxins9120389.

Finley, N.L. (2018) Revealing how an adenylate cyclase toxin uses bait and switch tactics in its activation PLOS Biology 27;16(2):e2005356. doi: 10.1371/journal.pbio.2005356.

Wood, C., Squire, M., Page, R., Finley,N.L.,  Actis, L. (2019) Structural and functional analysis of the Acinetobacter baumannii BlsA photoreceptor and regulatory protein. PLOS One doi.org/10.1371/journal.pone.0220918

Hong,J.C., Di Gioia, F., Jones, J.B., Turechek, W., Kokalis-Burelle, N., Johns, C.W., Finley, N.L., Ozores-Hampton, M., McCollum, G., Rosskopf, E.N. (2020) Defining Anaerobic Soil Disinfestation through Changes in the Microbiome Acta Hortic doi:10.17660/ActaHortic.2020.1270.10

Rosskopf, E.N, Di Gioia, F., Hong, J., Ozores-Hampton, M., Zhao, X., Black, Z., Gao, Z., Wilson, C., Thomas, J., Jones, J., Sattanno, K., DeLong, A., Swisher, M., Kokalis-Burelle, N., Wang, J., Li, Z., Shi, L., Pisani, C., Guo, H., Zhu, Q., Paudel, B., Johns, C.W., Finley, N.L.,  Muramoto, J., Albano, J., Shennan, C. (2020) Anaerobic Soil Disinfestation:  Areawide Project on Obstacles and Adoption Acta Hortic doi:10.17660/ActaHortic.2020.1270.3