Publications

The most up-to-date publication list is available on Saehyun's Google Scholar. 

Research Highlights

Postdoctoral Research @ University of California, Berkeley

15.  A. J. Rubin, T. T. Dao, A. V. Schueppert, S. Choi, J. T. Groves, A. Regev, A. K. Shalek, accepted, Science (2026).

14. S. Choi+, S. Kim+, T. J. Eisen, S. Morita, Jay T. Groves, Stimulation of CD28 or PD-1 Differentially Modulate the Propensity of LAT Condensate Nucleation by Activated T-cell Receptors, bioRxiv. 

13. S. Choi+, T. J. Eisen+, S. Morita, John Kuriyan, Jay T. Groves, Assembly of a Partial Signaling Unit Containing ITK and SLP76 Precedes T-cell Receptor Activation, in preparation.

12.  S. Choi, T. J. Eisen, S. Morita, Jay T. Groves, Single-molecule Displacement Imaging Reveals Low-yield Maturation of TCR-induced LAT Prenucleation Clusters into Signaling Condensates, in preparation

Doctoral Studies @ Penn State University

11. S. Choi, S. P. Liu, M. O. Meyer, P. C. Bevilacqua, C. D. Keating, Primitive Molecular Buffering by Low-Multivalency Coacervates, Journal of Physical Chemistry B, 129, 33, 8368–8381 (2025).

10. S. Choi+, A. R. Knoerdel+, C. E. Sing, C. D. Keating, Effect of polypeptide complex coacervate microenvironment on protonation of a guest molecule, Journal of Physical Chemistry B, 127, 26, 5978–5991 (2023). Citation: 21.

9. M. O. Meyer, R. Yamagami, S. Choi, C. D. Keating, P. C. Bevilacqua, RNA folding studies inside peptide-rich droplets reveal roles of modified nucleosides at the origin of life, Science Advances 9, eadh5152 (2023). Citation: 16.

8. M. O. Meyer, S. Choi, C. D. Keating, P. C. Bevilacqua, R. Yamagami, Structure-seq of tRNAs and other short RNAs in droplets and in vivo, Methods in Enzymology, 691, 81-126, (2023). Citation: 3.

7. S. Choi, M. O. Meyer, P. C. Bevilacqua, C. D. Keating, Phase-specific RNA accumulation and duplex thermodynamics in multiphase coacervate models for membraneless organelles, Nature Chemistry, 14, 1110–1117 (2022). Citation: 129.

6. F. P. Cakmak, S. Choi+, M. O. Meyer+, P. C. Bevilacqua, C. D.  Keating, Prebiotically-relevant low polyion multivalency can improve functionality of membraneless compartments, Nature Communications, 11, 5949 (2020). Citation: 180.  

Undergrad & Master Studies @ Ewha

5. I. Oh, S. Choi, Y. Jung, J. S. Kim, Entropic effect of macromolecular crowding enhances binding between nucleosome clutches in heterochromatin, but not in euchromatin, Scientific Reports 8, 5469 (2018). Citation: 15.

4. I. Oh, S. Choi, Y. Jung, J. S. Kim, Phase separation of a Lennard-Jones fluid interacting with a long, condensed polymer chain: implications to the nuclear body formation near chromosomes, Soft Matter, 11, 6450 (2015). Citation: 7.

3. S. Choi+, E. Jang+, J. S. Kim, In-layer stacking competition during ice growth, Journal of Chemical Physics, 140, 014701 (2014). Citation: 24.   

2. I. Oh, S. Choi, Y. Jung, J. S. Kim, Unusual size-dependence of effective interactions between collapsed polymers in crowded environments, Soft Matter, 10, 9098 (2014). Citation: 6.

1. M. Seo+, E. Jang+, K. Kim, S. Choi, J. S. Kim, Understanding anisotropic growth behavior of hexagonal ice on a molecular scale: a molecular dynamics simulation study, Journal of Chemical Physics, 137, 154503 (2012). Citation: 39.