The Maddaloni Team "Neurobiology of Circadian and Seasonal Rhythms" at the Institute of Psychiatry and Neuroscience of Paris investigates how the brain detects seasonal changes in light and temperature and translates them into adaptive shifts in sleep and circadian rhythms. Using cutting-edge tools to image and manipulate genetically defined neural circuits in mice, we are mapping the pathways that link environmental cues to biological timing, and how their disruption contributes to psychiatric conditions such as bipolar disorder, seasonal affective disorder, and schizophrenia. Ultimately, our goal is to translate these discoveries into new circuit-based therapeutic strategies for disorders with seasonal exacerbation.