研究業績

著書

4.  Charles G. Cranfield, Anna Kloda, Yury A. Nikolaev, Adam D. Martinac, Pietro Ridone, Navid Bavi, Omid Bavi, Evgeny Petrov, Andrew R. Battle, Takeshi Nomura, Paul R. Rohde, Yoshitaka Nakayama, Kadla R. Rosholm, Charles D. Cox, Matthew A. Baker and Boris Martinac. Mechanosensitivity of Ion Channels. European Biophysical Societies’ Association (EBSA) Encyclopedia of Biophysics, 1-11, 2018

 

3.  B. Martinac, P. Rhode, C. Cranfield and T. Nomura. Patch clamp electrophysiology for the study of bacterial ion channels in giant spheroplasts of E. coli. Springer, Methods Mol Biol. 966: 367-380, 2013

 

2.  Cranfield C, Kloda A, Petrov E, Battle A, Nomura T., Rohde P, Cox C and Martinac B. Techniques for Investigating the Mechanosensitivity of Ion Channels. Springer, Encyclopedia of Biophysics. 1433-1440, 2013

 

1.  Charles G. Cranfield, Ania Kloda, Takeshi Nomura, Evgeny Petrov, Andrew Battle, Maryrose Constantine and Boris Martinac. Force from lipids: A multidisciplinary approach to study bacterial mechanosensitive ion channels. In Mechanically Gated Channels and their Regulation. Springer, Mechanically Gated Channels and their Regulation Mechanosensitivity in Cells and Tissues, Vol 6: 1-33, 2012

原著論文

27.  Sawada Y, Nomura T, Martinac B, Sokabe M. A novel force transduction pathway from a tension sensor to the gate in the mechano-gating of MscL channel. Front Chem. 11: 1175443, 2023


26.  Ibrahim M Almanjahie, Ramzan Nazim Khan, Robin K Milne, Takeshi Nomura, Boris Martinac. Moving average filtering with  

      deconvolution (MAD) for hidden Markov model with filtering and correlated noise. Eur Biophys J. 48(4): 383-393, 2019

 

25.  Toshihiro Masuda, Kentarou Baba, Takeshi Nomura, Kazuya Tsujita, Tomo Murayama, Toshiki Itoh, Tomoka Takatani-Nakase, Masahiro Sokabe, Naoyuki Inagaki, Shiroh Futaki. An influenza-derived membrane tension-modulating peptide regulates cell movement and morphology via actin remodeling. Communications biology 2: 243-243, 2019

 

24.  Navid Bavi, Adam D. Martinac, D. Marien Cortes, Omid Bavi, Pietro Ridone, Takeshi Nomura, Adam P. Hill, Boris Martinac, Eduardo Perozo. Structural Dynamics of the MscL C-terminal Domain. Scientific Reports 7(1): 17229-17229, 2017

 

23Takeshi Nomura, Akiyuki Taruno, Makoto Shiraishi, Takashi Nakahari, Toshio Inui, Masahiro Sokabe, Douglas C. Eaton, Yoshinori Marunaka. Current-direction/amplitude-dependent single channel gating kinetics of mouse pannexin 1 channel: a new concept for gating kinetics. Scientific Reports 7(1): 10512-10512, 2017

 

22Takeshi Nomura, Masahiro Sokabe, Kenjiro Yoshimura. Voltage-Dependent Inactivation of MscS Occurs Independently of the Positively Charged Residues in the Transmembrane Domain. Biomed Res Int. 2016 2401657-2401657, 2016

 

21Takeshi Nomura, Charles D. Cox, Navid Bavi, Masahiro Sokabe, Boris Martinac. Unidirectional incorporation of a bacterial mechanosensitive channel into liposomal membranes. FASEB J. 29(10): 4334-4345, 2015

 

20.  Ibrahim M Almanjahie, R Nazim Khan, Robin K Milne, Takeshi Nomura, Boris Martinac. Hidden Markov analysis of improved bandwidth mechanosensitive ion channel data. Eur Biophy J. 44(7): 545-56, 2015

  

19.  Radomir I. Slavchov, Takeshi Nomura, Boris Martinac, Masahiro Sokabe, Frederick Sachs. Gigaseal Mechanics: Creep of the Gigaseal under the Action of Pressure, Adhesion, and Voltage. J. Phys. Chem. B. 118(44): 12660-12672, 2014

 

18.  Yong Wang, Yanxin Liu, Hannah A Deberg, Takeshi Nomura, Melinda Tonks Hoffman, Paul R Rohde, Klaus Schulten, Boris Martinac, Paul R Selvin. Single molecule FRET reveals pore size and opening mechanism of a mechano-sensitive ion channel. eLife 3 e01834, 2014

  

17.  Shaista Shaikh, Charles D Cox, Takeshi Nomura, Boris Martinac. Energetics of gating MscS by membrane tension in azolectin liposomes and giant spheroplasts. Channels (Austin, Tex.) 8(4): 321-6, 2014

 

16.  Michael Becker, Kirsten Börngen, Takeshi Nomura, Andrew R Battle, Kay Marin, Boris Martinac, Reinhard Krämer. Glutamate efflux mediated by Corynebacterium glutamicum MscCG, Escherichia coli MscS, and their derivatives. Biochim Biophys Acta. 1828(4): 1230-40, 2013

 

15.  Evgeny Petrov, Dinesh Palanivelu, Maryrose Constantine, Paul R. Rohde, Charles D. Cox, Takeshi Nomura, Daniel L. Minor, Boris Martinac. Patch-Clamp Characterization of the MscS-like Mechanosensitive Channel from Silicibacter pomeroyi. Biophys J. 104(7): 1426-1434, 2013

 

14.  Boris Martinac, Paul R Rohde, Charles G Cranfield, Takeshi Nomura. Patch clamp electrophysiology for the study of bacterial ion channels in giant spheroplasts of E. coli. Meth Mol Biol. (Clifton, N.J.) 966: 367-80, 2013

 

13.  Cox CD, Nomura T, Ziegler CS, Campbell AK, Wann KT, Martinac B. Selectivity mechanism of the mechanosensitive channel MscS revealed by probing channel subconducting states. Nat commun 4: 2137, 2013

 

12Takeshi Nomura, Charles G. Cranfield, Evelyne Deplazes, Dylan M. Owen, Alex Macmillan, Andrew R. Battle, Maryrose Constantine, Masahiro Sokabe, Boris Martinac. Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS. Proc. Natl. Acad. Sci. USA. 109(22): 8770-8775, 2012

 

11.  Ben Corry, Annette C. Hurst, Prithwish Pal, Takeshi Nomura, Paul Rigby, Boris Martinac. An improved open-channel structure of MscL determined from FRET confocal microscopy and simulation. J Gen Physiol. 136(4): 483-494, 2010

 

10Takeshi Nomura, Masahiro Sokabe, Kenjiro Yoshimura. Interaction between the cytoplasmic and transmembrane domains of the mechanosensitive channel MscS. BiophysJ. 94(5): 1638-45, 2008

 

9Takeshi Nomura, Masahiro Sokabe, Kenjiro Yoshimura. Lipid-protein interaction of the MscS mechanosensitive channel examined by scanning mutagenesis. Biophys J. 91(8): 2874-2881, 2006

 

8.  Kenjiro Yoshimura, Takeshi Nomura, Masahiro Sokabe. Loss-of-function mutations at the rim of the funnel of mechanosensitive channel MscL. Biophys J. 86(4): 2113-20, 2004

 

7.  Ohira Y, Nomura T, Kawano F, Sato Y, Ishihara A, Nonaka I. Effects of nine weeks of unloading on neuromuscular activities in adult rats. J Grav Physiol. 9(2): 49-59, 2002

 

6.  Fuminori Kawano, Takeshi Nomura, Akihiko Ishihara, Ikuya Nonaka, Yoshinobu Ohira. Effects of chronic hindlimb suspension on landing performance in response to head-down drop in rats. Uchu koku kankyo igaku 39(2): 21-9, 2002

 

5Takeshi Nomura, Fuminori Kawano, Myung Sun Kang, Jun Hak Lee, Eun Young Han, Chang Keun Kim, Yuzo Sato, Yoshinobu Ohira. Effects of long-term cold exposure on contractile muscles of rats. Jpn J Physiol. 52(1): 85-93, 2002

  

4.  F Kawano, T Nomura, A Ishihara, Nonaka, I, Y Ohira. Afferent input-associated reduction of muscle activity in microgravity environment. Neuroscience 114(4): 1133-1138, 2002

 

3T Nomura, F Kawano, A Ishihara, Y Sato, G Mitarai, S Iwase, A Kamiya, T Mano, Y Ohira. Enhanced Hoffman-reflex in human soleus muscle during exposure to microgravity environment. Neurosci Lett. 316(1): 55-57, 2001

 

2.  Y Ohira, T Tanaka, T Yoshinaga, F Kawano, T Nomura, Nonaka, I, DL Allen, RR Roy, VR Edgerton. Ontogenetic, gravity-dependent development of rat soleus muscle. Am J Physiol. 280(4): C1008-C1016, 2001

 

1.  大平充宣,野村健,河野史倫,野井倉武憲,井上勝一郎,重力荷重と骨代謝変化,リハビリテーション医学,36(9): 591-592, 1999

総説

4.  C. D. Cox, Y. Nakayama, T. Nomura, B. Martinac. The evolutionary 'tinkering' of MscS-like channels: generation of structural and functional diversity Pflugers Archiv-European Journal of Physiology 467(1): 3-13, 2015


3.  Boris Martinac, Takeshi Nomura, Gamma Chi, Evgeny Petrov, Paul R. Rohde, Andrew R. Battle, Alexander Foo, Maryrose Constantine, Rosalba Rothnagel, Sonia Carne, Evelyne Deplazes, Bruce Cornell, Charles G. Cranfield, Ben Hankamer, Michael J. Landsberg. Bacterial Mechanosensitive Channels: Models for Studying Mechanosensory Transduction. Antioxid. Redox Signal. 20(6): 952-969, 2014


2.  吉村建二郎,野村健,曽我部正博,細胞メカノセンサーの実体と機能,日本物理学会誌,62(1): 9-15, 2007


1.  Y Ohira, T Yoshinaga, T Nomura, F Kawano, A Ishihara, Nonaka, I, RR Roy, VR Edgerton. Gravitational unloading effects on muscle fiber size, phenotype and myonuclear number. Adv Space Res. 30(4): 777-781, 2002

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