40.臓器再生・疾病化のメカノバイオロジーへのバイオAFM応用

原子間力顕微鏡ハンドブック，in press

松﨑賢寿, 奥村龍, 吉川洋史

39.力学に基づく臓器疾病の機序解明

日本セラミックス協会誌，in press

松﨑賢寿, 奥村龍, 吉川洋史

38.Exploring bi-stability and hysteresis of the hybrid microstructures of graphene with carbon nanotubes.

arXiv:2606.04504  2026年6月3日

Ding, N. Sakurai, M. Shen, T. Inoue,  T. Mizuno, T. Matsuzaki,K.Suzuki, J. I. Enriquez, H. H. Halim, Y. Hamamoto, H .Y .Yoshikawa, Y. Morikawa, Y. Kobayashi 

URL: https://

37.Evaluation of the Spatial Distribution of Temperature of Aqueous Solutions under the Conditions of Laser Trapping for Molecular Assembly

 The Journal of Physical Chemistry B  2026年6月2日

R.Kawanami, K.Ide, T. Matsuzaki, N. Morimoto, A.Kagawa, K.Seo, T. Matsuura, H.Y.Yoshikawa 

 URL: pubs.acs.org/doi/10.1021/acs.jpcb.6c01705

36.Spatiotemporal Control of Formation of Dynamic Protein Fiber Assemblies via Photophysical Effects of a Focused Laser Beam

2012.Advanced Science 2026年5月17日

H.Y. Yoshikawa, R.Shirata, T.Takeshige, R. Yoshida, F.Kiryu, K.Takano, S.Matsumoto, R. Kawanami, N.Sawada, C.S.Wu, Y.H.Shih, H.Niinomi, T. Matsuzaki, S.Nakabayashi, T. Matsuura, T.Sugiyama, R.Kawamura, 

URL: advanced.onlinelibrary.wiley.com/doi/10.1002/advs.75531

任35.The YAP/TAZ–Tgfbr2–Stiffness Feedback Loop Governs Divergent Cell Fates of Muscle-Resident Mesenchymal Progenitors"

 SSRN(Preprint)  2026年4月

K.Iwamori, M.Horikiri, A.Kubo, K.Tokiwa, N. Sakurai, D. Mori, A. Nakamura, M.Kimura, N.Taniguchi, T. Kurosawa,L. Zhang, S.Watanabe, H. Y. Yoshikawa, T.Braun, A.Uezumi, T. Matsuzaki* ,S.Fukada 

URL: papers.ssrn.com/sol3/papers.cfm?abstract_id=6635513

34.細胞膜のナノ構造・物性を可視化する光干渉イメージング,

生物物理学会誌 ,Vol. 65 No. 6(通巻382号) ,

松﨑賢寿, 吉川洋史 

33.Pathological Angiogenesis Precedes the Onset of Aortic Dissection , 

bioRxiv , 

 K.Yoshioka, K.Iino, Y.Ito, T. Iba, T. Matsuzaki, N. Sakurai, M.Horie, T.Matsuyama, T. Wakabayashi, A. Matsui, Y.Yamamoto, T.Satoh, A.Goto, H. Y. Yoshikawa, H.Ando, D.Maeda, H.Takemura, H. Naito 

URL:https://doi.org/10.1101/2025.09.10.675317 

32. 超解像反射干渉顕微鏡の開発,

日本光学会「光学」2025,Vol.54(６)234-234, 

松崎賢寿*, 吉川洋史

31.Spatiotemporal Control of Formation of Dynamic Protein Fibre Networks via Photophysical Effects of a Focused Laser Beam"

ChemRxiv ,25（1 ），

H. Y. Yoshikawa  ,R. Shirata ,T. Takeshige ,F.Kiryu ,K.Takano ,S.Matsumoto ,N. Sawada ,C.S.Wu ,Y.-H.Shih ,H.Niinomi , T. Matsuzaki, ,S. Nakabayashi ,T. Sugiyama  ,R. Kawamura 

URL:https://doi.org/10.26434/chemrxiv-2025-sqjb0 

30. Simultaneous Visualization of Membrane Fluidity and Morphology Defines Adhesion Signatures of Cancer Cells, 

Proceedings of the National Academy of Sciences 121 (50) e2412914121, 2024,  

T. Matsuzaki,atsuzaki*(Double corresponding), M. Fujii, H. Noro, S. Togo, M. Watanabe, M. Suganuma, S. Sharma, N. Kobayashi, R. Kawamura, S. Nakabayashi, H. Y. Yoshikawa* .

URL: https://doi.org/10.1073/pnas.2412914121

29.(Japanese)Label-free 3D Tracking of Biological Micro-Objects Using RGB Pinholes, 

Japanese Journal of Applied Physics (Special Issues) 63, 4 04SP79 2024, 

D. Kim, T. Matsuzaki, H, Y. Yoshikawa, R. Kawamura*. 

URL: https://doi.org/10.35848/1347-4065/ad3969

28.Noninvasive Total Counting of Cultured Cells Using a Home-Use Scanner with a Pattern Sheet, iScience 27(3), 109170 2024

 M. Mizuno*, Y.Maeda, S. Sanami, T. Matsuzaki, H. Y. Yoshikawa, N. Ozeki, H. Koga, I. Sekiya. 

URL: https://doi.org/10.1016/j.isci.2024.109170

27.Mechanical Characterization of Mucus on Intestinal Tissues by Atomic Force Microscopy，Methods in molecular biology (Clifton, N.J.) 2763(2763) 403-414 2024, 

M. Horikiri, M. Taniguchi, H. Y. Yoshikawa, R. Okumura*,T. Matsuzaki*,

URL:https://pubmed.ncbi.nlm.nih.gov/38347430/

26.Advanced Interferometry with 3-D Structured Illumination Reveals the Surface Fine Structure of Complex Biospecimens, 

The journal of physical chemistry letters 15(4) 1097-1104 2024,

 T. Matsuzaki*R. Kawamura, A. Yamamoto, H. Takahashi, M. Fujii, S. Togo, Y. Yoneyama, F. Hakuno, S. Takahashi, M. Suganuma, S. Nakabayashi, S. Sharma, J. K. Gimzewski, H. Y Yoshikawa*

URL:https://pubs.acs.org/doi/10.1021/acs.jpclett.3c02767

25.Sialylation Shapes Mucus Architecture Inhibiting Bacterial Invasion in the Colon, 

Mucosal Immunology 2023,

 ●M. Taniguchi, R. Okumura, T. Matsuzaki,A. Nakatani, K. Sakaki, S. Okamoto, A. Ishibashi, H. Tani, M. Horikiri, N. Kobayashi, H. Y. Yoshikawa, D. Motooka, D. Okuzaki, S. Nakamura, T. Kida, A. Kameyama,K. Takeda*. 

URL: https://www.mucosalimmunology.org/article/S1933-0219(23)00049-1/fulltext 

24.Preparation of Mechanically-Patterned Hydrogels for Controlling the Self-Condensation of Cells, 

STAR Protocols 2023,

 ●T. Matsuzaki*(Triple corresponding authors), Y.Kawano, M. Horikiri, Y. Shimokawa, T. Yamazaki, N. Okuma, H. Koike, M. Kimura, R. Kawamura, Y. Yoneyama, Y. Furuichi, F. Hakuno, S. Takahashi, S. Nakabayashi, S. Okamoto, H. Nakauchi, H. Taniguchi, T. Takebe*, H. Y. Yoshikawa*.

URL:https://www.sciencedirect.com/science/article/pii/S2666166723004380

23.(Japanese)細胞接着の定量計測に基づく細胞組織の機能解明, 

化学と生物, 61(6), 269-273, 2023(Cover art selected.)

 ●T. Matsuzaki* (Correspondings*) et al., 

 URL: https://katosei.jsbba.or.jp/index.php?aid=1711&bt=on

22.Ion-Pair-Enhanced Double-Click Driven Cell Adhesion and Altered Expression of Related Genes, 

Bioconjugate Chemistry 34, 4, 638–644 2023   Front Cover selected,

 ●K. Kitagawa, N. Okuma, M. Yoshinaga, H. Takemae, F. Sato, S. Sato, S. Nakabayashi, H. Y. Yoshikawa, M. Suganuma, N. Luedtke,T. Matsuzaki* *(Double corresponding), M. Tera*

URL:https://pubs.acs.org/doi/full/10.1021/acs.bioconjchem.2c00569

21.Mechanical Guidance of Self-Condensation Patterns of Differentiating Progeny,

 iScience 105109-10510, 2022, Special Issue Selected. Japanese Journal Nikkei ONLINE futured. 

●T. Matsuzaki*(Triple correspondingauthors), Y. Shimokawa, H. Koike, M. Kimura, Y. Kawano, N. Okuma, R. Kawamura, Y. Yoneyama, Y. Furuichi, F. Hakuno, S. Takahashi, S. Nakabayashi, S. Okamoto, H. Nakauchi, H. Taniguchi, T. Takebe*, and H. Y. Yoshikawa*

URL:https://www.sciencedirect.com/science/article/pii/S2589004222013815 

20.Low Surface Potential with Glycoconjugates Determine Insect Cell Adhesion at Room-Temperature, 

J. Phys Chem Lett. 9494-9500, 2022 Front Cover selected (supplementary), 

●T. Matsuzaki*(double corresponding authors), D. Terutsuki*, S. Sato, K. Ikarashi, K. Sato, H. Mitsuno, R. Okumura, Y. Yoshimura, S. Usami, Y. Mori, M. Fujii. 

URL: https://pubs.acs.org/doi/full/10.1021/acs.jpclett.2c01673

19.Cell Membrane Fluidity and ROS Resistance Define DMSO Tolerance of Cryopreserved Synovial MSCs and HUVECs, 

Stem Cell Research and Therapy 13(1):177, 2022,

 ●M. Mizuno*,T. Matsuzaki,N. Ozeki, H.Katano, H. Koga, T. Takebe, H. Y. Yoshikawa, I. Sekiya 

URL:https://stemcellres.biomedcentral.com/articles/10.1186/s13287-022-02850-y 

18.Two-Photon Laser AblationandIn VivoWide-Field Imaging of Inferior Olive Neurons Revealed the Recovery of Olivocerebellar Circuits in Zebrafish, 

Int. J. Env. Res. Pub. Health 18(16), 8357 2021, ●K. Hiyoshi, K. Saito, N. Fukuda,  T. Matsuzaki,H. Y. Yoshikawa, S. Tsuda* 

URL: https://www.mdpi.com/1660- 4601/18/16/8357

17.Micromanipulation of Amyloplasts with Optical Tweezers in Arabidopsis Stems Plant, 

Biotech. 37(4) 405- 415 2020, 

Y. Abe, K. Meguriya,,T. Matsuzaki, T. Sugiyama, H. Y. Yoshikawa, M. T. Morita, M. Toyota* 

URL:https://www.jstage.jst.go.jp/article/plantbiotechnology/37/4/37_20.1201a/_article/- char/ja/

16.Stiffening of Cancer Cell Membranes is a Key Biophysical Mechanism of Primary and Tertiary Cancer Prevention with Green Tea Polyphenols, Chem Pharm Bull 68(12) 1123-1130 2020., 

M. Suganuma*, A. Rawangkan, P. Wongsirisin, N. Kobayashi, T. Matsuzaki,H. Y. Yoshikawa, T. Watanabe 

URL:https://www.jstage.jst.go.jp/article/cpb/68/12/68_c20-00300/_article 

15.Stiffness Distribution Analysis in Indentation Depth Direction Reveals Clear Mechanical Features of Cells and Organoids by Using AFM,  Applied Physics Express 13 097001 2020.,

 N. Kobayashi, S. Togo,T. Matsuzaki, K. Hashiseko, R. Kawamura, M. Suganuma, S. Nakabayashi, Y. Yoneyama, R. Ouchi, T. Takebe, H. Y. Yoshikawa* 

URL:https://iopscience.iop.org/article/10.35848/1882-0786/abaeb5

14.反射干渉顕微鏡による細胞接着のナノ計測：細胞接着に基づく生命現象の理解に向けてNano-Measurement of Cell Adhesion Using Interference Reflection Microscopy, 

応用物理学会　有機分子バイオエレクトロニクス分科会, 31(4), 231-236, 2020, 

●T. Matsuzaki et al.,

13.(Japanese)Elucidation of the Mechanical Properties of "Cells and Extercelluar Matrix" that Contribute to Organoid Formation,

 Medical Science Digest, Vol45 (10), 596-599, 2019, ●T. Matsuzaki et al., 

URL :オルガノイドによる消化器研究 オルガノイド形成に資する「細胞と外場」の力学特性の解明 | 文献情報 | J-GLOBAL 科学技術総合リンクセンター (jst.go.jp) 

12.Defining Lineage-Specific Membrane Fluidity Signatures that Regulate Adhesion Kinetics. 

Stem Cell Reports, 11, 852-860 2018,

 ●T. Matsuzaki, S. Matsumoto, T. Kasai, E. Yoshizawa, S. Okamoto, H. Y. Yoshikawa, H. Taniguchi, T. Takebe*.

URL:https://www.sciencedirect.com/science/article/pii/S2213671118303540?via=ihub

11.Adsorption of Galloyl Catechin Aggregates Significantly Modulates Membrane Mechanics in the Absence of Biochemical Cues, 

Phys. Chem. Chem. Phys., 19, 19937-19947 2017,

 ●T. Matsuzaki, H. Ito, V. Chevyreva, A. Makky, S. Kaufmann, K. Okano, N. Kobayashi, M. Suganuma, S. Nakabayashi, H. Y. Yoshikawa*, M. Tanaka* 

URL:https://pubs.rsc.org/en/content/articlelanding/2017/cp/c7cp02771k

10.細胞接着と培養場の硬さ : 物理化学観点からの生命現象の理解を目指して, 

化学とマイクロ・ナノシステム = Journal of the Society for Chemistry and Micro-Nano Systems : 化学とマイクロ・ナノシステム研究会誌 16(1) 21-26 2017, 

松﨑 賢寿, 吉川 洋史, 谷口 英樹, 武部 貴則

9.　反射干渉法〜ソフト界面の非侵襲なのイメージング, 生物物理学会, 57(6), 318-322 Aug 2017,

吉川洋史，●松崎賢寿

URL:https://www.jstage.jst.go.jp/article/biophys/57/6/57_318/_pdf

8.(Japanese) 人工細胞外基質の硬さと器官原基の自己組織, 

日本バイオマテリアル学会誌, 35(1), 58-61 2017, 2024, 

●T. Matsuzaki et al.,

7.Biophysical Approach to Mechanisms of Cancer Prevention Treatment with Green Tea Catechins,

Molecules, 21, 1566-1583 2016,

 M. Suganuma*, A. Takahashi, T. Watanabe, K. Iida,T. Matsuzaki, , H. Y. Yoshikawa, H. Fujiki 

URL: https://www.mdpi.com/1420-3049/21/11/1566

6.Quantitative Comparison of Cancer and Normal Cell Adhesion using Organosilane Monolayer Templates: An Experimental Study on The Anti-Adhesion Effect of Green Tea Catechins, 

In Vitro Cellular & Developmental Biology-Animal, 52, 799-805 2016,

 R. Sakamoto, E. Kakinuma, K. Masuda, Y. Takeuchi, K. Ito, K. Iketaki, T. Matsuzaki, S. Nakabayashi, H. Y. Yoshikawa, H. Yamamoto, Y. Sato, T. Tanii*

URL:https://link.springer.com/article/10.1007/s11626-016-0049-6

5.Quantitative Evaluation of Cancer Cell Adhesion to SAM-Patterned Substrates by Reflection Interference Contrast Microscopy., 

J. Phys. Chem. B,120, 1221-1227 2016,

 ●,T. Matsuzaki, K. Ito, K. Masuda, E. Kakinuma, R. Sakamoto, K. Iketaki, H. Yamamoto, M.Suganuma, N. Kobayashi, S. Nakabayashi, T. Tanii, H. Y. Yoshikawa*. 

URL: https://pubs.acs.org/doi/10.1021/acs.jpcb.5b11870

4.Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation, 

Cell Stem Cell, 16, 556-565 2015,

 T. Takebe*, M. Enomura, E. Yoshizawa, M. Kimura, H. Koike, U. Yasuharu,  T. Matsuzaki,T. Yamazaki, T. Toyohara, K. Osafune, H. Nakauchi, H. Y. Yoshikawa, H. Taniguchi, Front cover selected, Nature method highlights. 

URL : https://www.cell.com/fulltext/S1934-5909%2815%2900115-0

3.Reconstruction of Joint Hyaline Cartilage by Autologous Progenitor Cells Derived from ear elastic cartilage, 

Stem Cells, 32 816–821 2014, M. Mizuno, S. Kobayashi, T. Takebe, H. Kan, Y. Yabuki,T. Matsuzaki, , H. Y. Yoshikawa, S. Nakabayashi, L. JeongIk, J. Maegawa, H. Taniguchi* 

URL: https://academic.oup.com/stmcls/article/32/3/816/6422989

2.High Contrast Visualization of Cell–Hydrogel Contact by Advanced Interferometric Optical Microscopy,

J. Phys. Chem. Lett., 5 253–257 2014, 

●T. Matsuzaki, G. Sazaki, M. Suganuma, T. Watanabe, T. Yamazaki, M. Tanaka, S. Nakabayashi, H. Y. Yoshikawa*. 

URL: https://pubs.acs.org/doi/10.1021/jz402463u

1.Quantitative Evaluation of Adhesion of Osteosarcoma Cells to Hydrophobic Polymer Substrate with Tunable Elasticity

J. Phys. Chem. B, 116 8024-8030, 2012.

H. Y. Yoshikawa, J. Cui, K. Kratz, T. Matsuzaki, S. Nakabayashi, A. Marx, U. Engel, A. Lendlein*, and M.Tanaka*

URL: https://pubs.acs.org/doi/10.1021/jp212385p