Systems Engineering for Biotechnology
Research Group
Welcome to the blog of the research group led by Sebastián Espinel Ríos in the School of Chemical and Bioprocess Engineering at University College Dublin (UCD).
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The Systems Engineering for Biotechnology group is part of UCD’s School of Chemical and Bioprocess Engineering in Dublin, Ireland.
Overview
Overview
Our group develops tailored computational methods for advanced modeling, optimization, and control, enabling and supporting novel biotechnological applications and the digitalization of the biotechnology industry. This includes mechanistic, AI-based, and hybrid strategies applied across in-cell, external, and multiscale levels. To achieve this, we take a systems-of-systems approach that integrates concepts from Process Systems Engineering (PSE), Systems Biology (SB), and Scientific Machine Learning (SciML).
We focus on three core areas in the context of bioprocesses and biosystems:
Digital twin technologies, model reduction, and knowledge transfer.
Methods for multilevel optimization and control, including soft sensors.
Software development for bioprocess digitalization and automation.
Overview of our research areas toward advancing the digitalization of the biotechnology industry.
Systems Engineering for Biotechnology: a unifying framework integrating Systems Biology (SB) and Process Systems Engineering (PSE). https://doi.org/10.3389/fsysb.2025.1583534.
Interested in joining the group?
Interested in joining the group?
We welcome applications from prospective students and researchers. See current opportunities here.
Group outings
Group outings
We value opportunities to connect beyond our research activities and foster a supportive and enjoyable group environment.
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