Publications

Peer Reviewed Publications

• • Jourdan E Lakes, Xu Fu, Brock T Harvey, Khaga R Neupane, Surya P Aryal, Jessica L Ferrell, Michael D Flythe, Christopher I Richards. Impact of nicotine and cotinine on macrophage inflammatory plasticity via vesicular modifications in gastrointestinal bacteria. Anaerobe 2023

https://doi.org/10.1016/j.anaerobe.2023.102787 

• •  Mohit Kumar, Jack Keady, Surya P Aryal, Marissa Hessing-Alpers, Christopher I Richards, Jill R Turner. The Role of Microglia in Sex-and Region-Specific Blood-Brain Barrier Integrity During Nicotine Withdrawal.  Biological Psychiatry Global Open Science 2023  

https://www.bpsgos.org/article/S2667-1743(23)00111-8/fulltext

• • Khaga R Neupane, Geraldine S Ramon, Brock Harvey, Ben Chun, Surya P Aryal, Abdullah A. Masud, J. Robert McCorkle, Jill M. Kolesar, Peter M. Kekenes-Huskey, Christopher I. Richards. Programming Cell-Derived Vesicles with Enhanced Immunomodulatory Properties.  Advanced Healthcare Materials 2023

https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.202301163

• • Byeong J Chun, Surya P Aryal, Peter Varughese, Bin Sun, Joshua A Bruno, Chris I Richards, Adam D Bachstetter, Peter M Kekenes-Huskey. Purinoreceptors and ectonucleotidases control ATP-induced calcium waveforms and calcium-dependent responses in microglia: Roles of P2 receptors and CD39 in ATP-stimulated microglia. Frontiers in Physiology 2023    

https://www.frontiersin.org/articles/10.3389/fphys.2022.1037417/full 

• • Surya P Aryal, Mengfan Xia, Pavel I Ortinski, Christopher I Richards. Study of Calcium Signaling in Astrocytes with a novel Endoplasmic Reticulum Targeted GCaMP Sensor. Current Protocols in Neuroscience 2022

 https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/cpz1.491

• • Surya P Aryal, Mengfan Xia, Ebubechi Adindu, Caroline Davis, Pavel I Ortinski, Christopher I Richards. An Endoplasmic Reticulum Targeted Calcium Probe to Study Calcium Signaling in Astrocytic Processes. Analytical Chemistry 2022 

https://pubs.acs.org/doi/10.1021/acs.analchem.1c04321

• • Surya P Aryal, Khaga R Neupane, Abdullah A Masud, Christopher I Richards. Characterization of Astrocyte Morphology and Function Using a Fast and Reliable Tissue Clearing Technique. Current Protocols in Neuroscience 2021      

https://doi.org/10.1002/cpz1.279

• • Surya P Aryal, Xu Fu, Joree N Sandin, Khaga R Neupane, Jourdan E Lakes, Martha E Grady, Christopher I Richards. Nicotine Induces Morphological and Functional Remodeling in Astrocytes via Nicotinic Receptor Activity. Glia 2021    

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258843/

• • Abdullah Al Masood, S.M. Arefin, Fatema Fairooz, Xu Fu, Faruk Moonschi, Bernadeta Srijanto, Khaga Neupane, Surya P Aryal, Rosemary Calabro, Doo-Young Kim, C. Collier, Mustafa Chowdhury, Christopher Richards, Photoluminescence Enhancement, Blinking Suppression, and Improved Biexciton Quantum Yield of Single Quantum Dots in Zero Mode Waveguides. Journal of Physical Chemistry Letters 2021    

https://pubs.acs.org/doi/abs/10.1021/acs.jpclett.1c00450

• • Surya P Aryal, Xu Fu, Abdullah A Masood, Khaga R Neupane, Christopher I Richards. Single-Molecule Studies of Membrane Receptors from Brain Region Specific Nanovesicles. Bioprotocol 2021   

https://bio-protocol.org/e4018

• • Khaga R Neupane, J. Robert McCorkle, Timothy J Kopper, Jourdan E Lakes, Surya P Aryal, Abdullah Masud, Aaron A Snell, John C. Gensel, Jill Kolesar, Christopher I Richards. Macrophage Engineered Vesicles for Therapeutic Delivery and Bidirectional Reprogramming of Immune Cell Polarization. ACS Omega 2021  

https://pubs.acs.org/doi/abs/10.1021/acsomega.0c05632

• •  Joree N Sandin, Surya P Aryal, Thomas Wilkop, Christopher I Richards, Martha E Grady. Near Simultaneous Laser Scanning Confocal and Atomic Force Microscopy (Conpokal) on Live Cells. Journal of Visualized Experiments, 2020    

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680637/

• •  Bindu Modi, Niranjan Koirala, Surya P Aryal, Jiban Shrestha, Shishir Koirala, Jitendra Upadhyaya, Ram Chandra Basnyat, Najat Marraiki, Gaber El-Saber Batiha. Tinospora cordifolia (Willd.) Miers: Phytochemical Composition, Cytotoxicity, Proximate Analysis, and their Biological Activities. Cell and Molecular Biology 2021  

https://www.cellmolbiol.org/index.php/CMB/article/view/3939

• •  Bindu Modi, Kabita K Shah, Jiban Shrestha, Prakash Shrestha, Anju Basnet, Injila Tiwari, Surya P Aryal. Morphology, biological activity, chemical composition, and medicinal value of Tinospora cordifolia (Willd.) miers. Advanced Journal of Chemistry B 2020  

http://www.ajchem-b.com/article_118153.html

• •  Kabita Kumari Shah, Bindu Modi, Bibek Lamsal, Jiban Shrestha, Surya P Aryal. Bioactive compounds in tomato and their roles in diseases prevention: A review. Fundamental and Applied Agriculture 2020  

http://www.f2ffoundation.org/faa/index.php/home/article/view/92

• •  Prakash Shrestha, Bindu Modi, Surya P Aryal, Hari Timilsina, Jiban Shrestha, Ram Chandra Basnyat. Total phenolic and flavonoids content, antioxidant activity, phytochemical, and nutritional analysis of Castanopsis indica (Indian chestnut). Natural Resources and Sustainable Development 2020  

10.31924/nrsd.v10i2.053

• •  Surya P Aryal, Mandira P Adhikari. Study of composite electrodes of Fe2O3/graphite and MnFe2O3/PANI in microbial fuel cell. Journal of Alpine Chemistry 2018   

https://figshare.com/articles/journal_contribution/Journal_of_Alpine_Chemistry_March_2018_pdf/12818795

Conferences, Posters, and Talks

• •  Surya P Aryal, Christopher I Richards. Application of gelatin polymer-based approaches in fluorescence imaging of the brain vasculature. American Chemical Society Spring 2023, Indianapolis IN (Invited talk, remote)  

  • Surya P Aryal, Mengfan Xia, Pavel Ortinski, Christopher I Richards. ER-GCaMP6f: An Endoplasmic Reticulum Targeted Calcium Probe to Study Calcium Signaling in Astrocytic Soma and Processes. Neuroscience 2022 (Society for Neuroscience) November 2022, San Diego CA 

  • Surya   P   Aryal, Yongwook   Song, Xu   Fu, Christopher   I   Richards. Single   Molecule Fluorescence  Imaging  to  Study  Nicotinic  Acetylcholine  Receptors  in  the  Brain. Gordon Molecular   and   Cellular   Neurobiology Seminar(Functional   Integration   of   Neural Mechanisms in Health and Disease):Invited Talk,July 2022, Ventura CA

  • Surya  P  Aryal, Mengfan  Xia,  Pavel  Ortinski,  Christopher  I  Richards.  Development  of  An Endoplasmic Reticulum Targeted Calcium Probe to Study Calcium Signaling in Astrocytic Soma   and   Processes.Gordon   Molecularand   CellularNeurobiology Conference (Emerging   Technologies   to   Study   Nervous   System   Development,   Function   and Neurological Disease)July2022, Ventura CA

  • Surya P Aryal, Mengfan Xia, Pavel Ortinski, Christopher I Richards. ER-GCaMP6f: An Endoplasmic Reticulum Targeted Calcium Probe to Study Calcium Signaling in Astrocytic Soma and Processes. Naff Symposium April 2022, University of Kentucky

  • Surya P Aryal, Mengfan Xia, Pavel Ortinski, Christopher I Richards. An Endoplasmic Reticulum Targeted Calcium Probe to Study Calcium Signaling in Astrocytic Processes. Substance Use Research Day March 2022, University of Kentucky 10.13140/RG.2.2.35645.95207

  • Surya P Aryal, Christopher I Richards.Single Molecule Fluorescence Imaging of Synaptic Nicotinic Receptors Reveals Nicotine-induced Stoichiometric Shifts. Biophysical Society Annual Meeting February, 2022, San Francisco, California https://www.cell.com/biophysj/pdf/S0006-3495(21)02305-5.pdf

  • Surya P Aryal, Christopher I Richards. Study of synaptic membrane receptors by a TIRF based single molecule method. American Chemical Society National Meeting (SciMix Session) August 2021, Atlanta, Georgia https://www.morressier.com/o/event/611a5aa65faad60014d170a3/article/612e2cf5cb003360fe3aa305

  • Surya P Aryal, Christopher I Richards. Study of synaptic membrane receptors by a TIRF based single molecule method. American Chemical Society National Meeting (Division of Biological Chemistry) August 2021, Atlanta, Georgia https://www.morressier.com/o/event/611a5aa65faad60014d170a3/article/612e2cf5cb003360fe3aa305

  • Surya P Aryal, Christopher I Richards. Study of dopamine-induced functional adaptations in astrocytes. American Chemical Society Middle Atlantic Regional Meeting June 2021

  • Surya P Aryal, Christopher I Richards. Single Molecule Characterization of Synaptic Nicotinic Acetylcholine Receptors (nAChRs). Chemistry Graduate Student Association Mini Conference April 2021

  •  Surya P Aryal, Christopher I Richards. Understanding the role of dopamine in astrocyte mediated brain signaling and function. Biophysical society annual meeting (online) February 2021 https://www.cell.com/biophysj/fulltext/S0006-3495(20)33087-3

  •  Surya P Aryal, Christopher I Richards. Role of Dopamine in Astrocyte-mediated Brain Signaling and Function. PITTCONN Conference 2021

  •  Surya P Aryal, Christopher I Richards. Nicotine induces time dependent morphological rearrangement in astrocytes. Life Science Exhibit Webinar 2021

  •  Surya P Aryal, Christopher I Richards. Understanding nicotine induced morphological and functional changes in astrocytes. Biophysical society annual meeting in San Diego, California February 2020   https://doi.org/10.1016/j.bpj.2020.11.2180 

  • .Surya P Aryal, Christopher I Richards. “Understanding the effects of nicotine on the brain using cleared tissue technique. TODD symposium, Department of pharmaceutical sciences, University of Kentucky 2019