Inflammatory Bowel Disease

Goal: Study the role of CD40-TRAF signlaing in Inflammatory Bowel Disease (IBD).  

Background

CD40 is a major driver of various inflammatory and autoimmune diseases. This makes CD40 a recognized therapeutic target against these disorders. We utilize transgenic mice made in the laboratory and pharmacologic approaches to study the role of CD40-TRAF signaling in inflammatory bowel disease (IBD).