The Next-generation Structure Lab. at Hankyong National University is a research group whose members major in structural engineering based on reinforced concrete (RC) and prestressed concrete (PSC) structures. Its research, however, is not limited to concrete structures and extends to precast concrete and off-site construction (OSC), steel–concrete composite structures, strengthening of existing structures, and eco-friendly construction materials that respond to global climate change. Based on an understanding of material properties and the mechanical behavior of structures, the group combines mechanics-based modeling, finite element analysis, and large-scale testing to achieve better structural systems for the future construction industry, with a focus on structural efficiency (material saving, sectional optimization, and construction method) and energy efficiency related to thermal performance and CDW (construction and demolition waste). The research covers mechanical models for RC and PSC members under combined loads, precast joints and composite members, and strengthening with fabric-reinforced cementitious matrix (FRCM). It also develops advanced and eco-friendly materials such as recycled aggregate concrete, UHPC, lightweight concrete, and high thermal performance concrete using industrial by-products, and validates their structural performance. In addition, the group builds AI- and image-based assessment tools for existing structures, including digital image correlation (DIC), convolutional neural networks (CNN), and reliability analysis. The next stage is a life-cycle framework that links sustainable OSC components with digital-twin-based condition assessment. These efforts are supported by national research programs, including the NRF-funded national and international reserach programs, and their results are shared through international journals, conferences, and patents.