Jennifer Pham

Ph.D. in Biomedical Sciences

Education

Department of Microbiology, Immunology and Genetics, North Texas Eye Research Institute, UNTHSC
- Visual Sciences Discipline
M.S. in Biomedical Sciences, UNTHSC
B.S. in Biochemistry, Texas Woman's University

Contact

Area of Research

My current research focuses on assessing the effectiveness of SA derivatives - hybrid molecules that contain antioxidant and nitric oxide-donating properties - in protecting retinal ganglion cells. Using a range of models, including in vitro, in vivo, and ex vivo testing in both rodents and human explants, my aim is to uncover the mechanism(s) by which these SA derivatives operate. My background lies in nanomedicine, encompassing polymeric/liposomal nanoparticle synthesis, drug encapsulation, and targeted delivery.

Publications

2023

Kodati B, Zhang W, He S, Pham JH, Beall KJ, Swanger ZE, Krishnamoorthy VR, Harris PE, Hall T, Tran AV, Chaphalkar RM, Chavala SH, Stankowska DL and Krishnamoorthy RR (2023) The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats. Front. Ophthalmol. 3:1185755. doi: 10.3389/fopht.2023.1185755
Pham, J. H., & Stankowska, D. L. (2023). Mitochondria-associated endoplasmic reticulum membranes (MAMS) and their role in glaucomatous retinal ganglion cell degeneration—a mini review. Frontiers in Neuroscience, 17. https://doi.org/10.3389/fnins.2023.1198343

2022

Pham, J.H.; Johnson, G.A.; Rangan, R.S.; Amankwa, C.E.; Acharya, S.; Stankowska, D.L. Neuroprotection of Rodent and Human Retinal Ganglion Cells In Vitro/Ex Vivo by the Hybrid Small Molecule SA-2. Cells 2022, 11, 3741. https://doi.org/10.3390/cells11233741

Presentations

2023

Paper (Oral Presentation): Jennifer Hien Pham, Wei Zhang, Kim-Tuyen T. Le, Bindu Kodati, Charles E. Amankwa, Rachel E. Engelland, Gretchen Annika Johnson, Amalendu Ranjan, Suchismita Acharya, Dorota Luiza Stankowska; Neuroprotection of Rodent Retinal Ganglion Cells using Hybrid Molecule SA-10 and its PLGA Nanosuspension. ARVO Annual Meeting April 23-27, 2022.
Poster: Pham, J., Kodati B., Johnson, G., Acharya, S., Stankowska, D. (2023). Neuroprotection of Rodent Retinal Ganglion Cells using Hybrid Molecule SA-10. UNTHSC Research Appreciation Day 2023.

2022

Poster: Pham, J., Johnson, G., Acharya, S., Stankowska, D. (2022). Neuroprotection of human and rodent retinal ganglion cells by a hybrid small molecule, SA-2. Poster Presentation. ARVO Annual Meeting May 1-4, 2022.
Poster: Pham, J., Johnson, G., Suchismita, A., Stankowska, D. (2022). Neuroprotection of human and rodent retinal ganglion cells by a hybrid antioxidant-nitric oxide donor small molecule, SA-2. UNTHSC Research Appreciation Day 2022.

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