Laboratory of Endocrine and Neuropsychiatric Disorders

Research/Review Papers

• • Wei G, Sirohi S^¶ and Walker BM (2022) Dysregulated kappa-opioid receptors in the medial prefrontal cortex contribute to working memory deficits in alcohol dependence Addict Biol 27:e13138.

• • Leon Z ^Ώ, Shah K, Bailey LS, Karkhanis AN and Sirohi S* (2021) Patterned Feeding of a Hyper-palatable Food (Oreo Cookies) Reduces Alcohol Drinking in Rats. Front Behav Neurosci 15:725856.

Editors’ Choice - chosen for the Motivation and Reward- Editor’s Pick 2022 .

• • Shah K^Ώ, Shaw C^Ώ and Sirohi S* (2020) Reduced Alcohol Drinking Following Patterned Feeding: Role of Palatability and Acute Contingent Availability. Physiol Behav 224:113020.

• • Brutman J, Davis JF and Sirohi S* (2020) Behavioral and Neurobiological Consequences of Hedonic Feeding on Alcohol Drinking. Current Pharmaceutical Design 26 (20): 2309-2315.

• • Villavasso S ^Ώ, Shaw C ^Ώ, Skripnikova E, Shah K, Davis JF, Sirohi S* (2019) Nutritional Contingency Reduces Alcohol Drinking by Altering Central Neurotransmitter Receptor Gene Expression in Rats. Nutrients 11 (11): 2731.

• • Brutman J, Sirohi S, and Davis JF (2019) Recent advances in the neurobiology of altered motivation following bariatric surgery. Current Psychiatry Reports 21(11):117.

• • Brutman J, Sirohi S^¶, and Davis JF (2019) Examining the Impact of Estrogen on Binge Feeding, Food Motivated Behavior and Body Weight in Female Rats. Obesity 27(10): 1617-1626.

• • Massaly N, Copits BA, Wilson-Poe AR, Hipólito L, Markovic T, Yoon HJ, Liu S, Walicki MC, Bhatti DL, Sirohi S, Klaas A, Walker BM, Neve R, Cahill CM, Shoghi KI, Gereau RW 4th, McCall JG, Al-Hasani R, Bruchas MR, Morón JA (2019) Pain-Induced Negative Affect Is Mediated via Recruitment of The Nucleus Accumbens Kappa Opioid System. Neuron 102 (3):564-573.e6.

• • Go BS, Sirohi S and Walker BM (2019) The role of matrix metalloproteinase-9 in negative reinforcement learning and plasticity in alcohol dependence. Addiction Biology 25 (2): e12715.

• • Sirohi S*, Skripnikova E and Davis JF (2018) Vertical Sleeve Gastrectomy Attenuates Hedonic Feeding Without Impacting Alcohol Drinking in Rats. Obesity 27(4):603-611.

• • Sirohi S, Richardson BD, Lugo JM, Rossi DJ and Davis JF (2017) Impact of Roux en Y Gastric Bypass Surgery on Appetite, Alcohol Intake Behaviors, and Midbrain Ghrelin Signaling in the Rat. Obesity 25 (7): 1228-1236.

Editors’ Choice article for the July issue of Obesity.

• • Sirohi S*, Vancleef A, and Davis JF (2017) Intermittent access to a nutritionally complete high-fat diet attenuates alcohol drinking in rats. Pharmacol Biochem Behav 153:105-115.

• • Sirohi S, Vancleef A, and Davis JF (2017) Patterned Feeding Induces Neuroendocrine, Behavioral, and Genetic Changes that Promote Palatable Food Intake. Int J Obes* 41:412-419. One of the featured articles: International Journal of obesity – Mar 2017

• • Sirohi S, Vancleef A, and Davis JF (2017) Binge-like intake of HFD Attenuates Alcohol Intake in Rats. Physiol Behav 178: 187-195.

• • Sirohi S* and Tiwari AK (2016) Invited Editorial - Pain in the management of opioid use disorder. J Pain Res 9:963-966.

• • Sirohi S*, Schurdak JD, Seeley RJ, Benoit SC and Davis JF (2016) Central & peripheral glucagon-like peptide-1 receptor signaling differentially regulate addictive behaviors Physiol Behav 161:140-4.

• • Sirohi S and Walker BM (2016) Species differences in zyklophin efficacy at kappa opioid receptors Alcohol 51:43-9.

• • Sirohi S and Walker BM (2015) Maturational changes in the medial prefrontal κ-opioid receptors constitutive activity. J Neurochem 135: 659-65.

• • Kissler JL^¶, Sirohi S^¶, Reis DJ, Jansen HT, Quock RM, Smith DG and Walker BM (2014) The ‘One-Two’ punch of alcoholism: Role of the Central Amygdala Dynorphin/Kappa Opioid Receptors. Biol Psychiatry* 75: 774-82.

^¶= Co-first authors, equal contribution

Commentary by: - Markus Heilig, Jesse R. Schank (2014) Kappa-Opioid Receptor Antagonism: A Mechanism for Treatment of Relief Drinking? Biological Psychiatry 75- 10: 750-751.

Press Release: Biological Psychiatry - May 22, 2014

http://www.biologicalpsychiatryjournal.com/pb/assets/raw/Health%20Advance/journals/bps/BPS140522_A_New_Target_for_Alcoholism_Treatment_Kappa_Opioid_Receptors.pdf

Biological Psychiatry 2014 journal metrics- One of the most highly cited 2014 original articles for Biological Psychiatry to date.

• • Sirohi S, Bakalkin G and Walker BM (2012) Alcohol-induced plasticity in the dynorphin/kappa-opioid receptor system. Front Mol Neurosci 5, 95: 1-12.

• • Navani DM, Sirohi S, Madia PA and Yoburn BC (2011) The role of opioid antagonist efficacy and constitutive opioid receptor activity in the opioid withdrawal syndrome in mice. Pharmacol Biochem Behav 99:671-675.

• • Sirohi S and Madia PA (2009) NMDA receptor and opioid analgesic tolerance. Int J Pharm Clin Res 1:1-3.

• • Madia PA, Dighe SV, Sirohi S, Walker EA and Yoburn BC (2009) Dosing protocol and analgesic efficacy determine opioid tolerance in mouse. Psychopharmacology 207:413-422.

• • Sirohi S, Dighe SV, Madia PA and Yoburn BC (2009) The relative potency of inverse opioid agonists and a neutral opioid antagonist in precipitated withdrawal and antagonism of analgesia and toxicity. J Pharmacol Exp Ther 330:513-519.

• • Dighe SV, Madia PA, Sirohi S and Yoburn BC (2009) Continuous morphine produces more tolerance than intermittent or acute treatment. Pharmacol Biochem Behav 92:537-542.

• • Kumar P, Sunkaraneni S, Sirohi S, Dighe SV, Walker EA and Yoburn BC (2008) Hydromorphone efficacy and treatment protocol impact on tolerance and mu-opioid receptor regulation. Euro J Pharmacol 597:39-45.

• • Sirohi S, Dighe SV, Walker EA and Yoburn BC (2008) The analgesic efficacy of fentanyl: relationship to tolerance and mu-opioid receptor regulation. Pharmacol Biochem Behav 91:115-120.

• • Sirohi S, Kumar P and Yoburn BC (2007) mu-Opioid receptor upregulation and functional supersensitivity are independent of antagonist efficacy. J Pharmacol Exp Ther 323:701-707.

• • Pawar M, Kumar P, Sunkaraneni S, Sirohi S, Walker EA and Yoburn BC (2007) Opioid agonist efficacy predicts the magnitude of tolerance and the regulation of mu-opioid receptors and dynamins-2. Euro J Pharmacol 563:92-101.

• • Singh SK, Sirohi S, Verma S and Mishra DN (2005) Dendrimers-potential applications in pharmacy. The Pharma Review 3:29-36.

• • Sirohi S and Ahuja M (2005) Nocebo- The power of belief and its clinical implications. The Antiseptic 102:38-40.

• • Singh S, Sirohi S, Verma S, Kumar SGVijay and Mishra DN (2004) Nootropics- the memory enhancers. The Antiseptic 101:598-600.

Book Chapters

• Brutman J, Sirohi S and Davis JF (2021) Animal Models of Binge Eating: Hedonic Feeding and Alcohol Intake. In: Avena N.M. (eds) Animal Models of Eating Disorders-2^nd Edition. Neuromethods: Vol 161, 9 163-171. humana, New York, NY.

• Singleton B, Landry S, Sirohi S and Al-Dahir S (2018) Vitamins, amino acids and drugs and formulations used in nutrition. Side Effects of Drugs Annual: Vol 40, 431-446.

• Al-Dahir S, Vithlani N, Smith A, Davis JF and Sirohi S* (2017) Vitamins, amino acids and drugs and formulations used in nutrition. Side Effects of Drugs Annual: Vol 39, 345-358.

*Corresponding author ^Ώ Undergraduate Researcher ^¶ Equally contributing author